Themed collection Analytical Methods HOT Articles 2021

81 items - Showing page 1 of 2
Minireview

Recent advances in selective formaldehyde detection in biological and environmental samples by fluorometric and colorimetric chemodosimeters

In this minireview, we have comprehensively discussed recent advances in the design principles and sensing mechanisms of developed probes and their biological/environmental applications in selective formaldehyde detection.

Graphical abstract: Recent advances in selective formaldehyde detection in biological and environmental samples by fluorometric and colorimetric chemodosimeters
From the themed collection: Analytical Methods HOT Articles 2021
Minireview

The emerging role of 3D-printing in ion mobility spectrometry and mass spectrometry

3D-printing enables the rapid prototyping of ion mobility (IMS) and mass spectrometry (MS) gadgets. The RepRap components are suitable for building cost-efficient robots and MS imaging systems. In this review, we present current trends.

Graphical abstract: The emerging role of 3D-printing in ion mobility spectrometry and mass spectrometry
Tutorial Review

Beyond principal components: a critical comparison of factor analysis methods for subspace modelling in chemistry

Principal components analysis (PCA) is widely used in analytical chemistry, but is only one type of broader range of factor analysis tools that are described in this article.

Graphical abstract: Beyond principal components: a critical comparison of factor analysis methods for subspace modelling in chemistry
From the themed collection: Analytical Methods HOT Articles 2021
Tutorial Review

Taylor dispersion analysis in fused silica capillaries: a tutorial review

Observations of band broadening under well-controlled laminar flow enable absolute, calibration-free determinations of diffusion coefficient.

Graphical abstract: Taylor dispersion analysis in fused silica capillaries: a tutorial review
From the themed collection: Analytical Methods HOT Articles 2021
Critical Review

Portable point-of-care diagnostic devices: an updated review

This review highlights recent examples of point-of-care (POC) diagnostics for detecting nucleic acids, proteins, bacteria, and other biomarkers, all focused on highlighting the positive impact of POC on society and human health.

Graphical abstract: Portable point-of-care diagnostic devices: an updated review
From the themed collection: Analytical Methods HOT Articles 2021
Open Access Critical Review

Molecular diagnostics in the era of COVID-19

As the COVID-19 pandemic continues to escalate globally and acquires new mutations, accurate diagnostic technologies continue to play a vital role in controlling and understanding the epidemiology of this disease.

Graphical abstract: Molecular diagnostics in the era of COVID-19
Critical Review

Analytical applications of single particle inductively coupled plasma mass spectrometry: a comprehensive and critical review

Real-world applications of single-particle ICP-MS are comprehensively and critically reviewed.

Graphical abstract: Analytical applications of single particle inductively coupled plasma mass spectrometry: a comprehensive and critical review
From the themed collection: Analytical Methods HOT Articles 2021
Critical Review

Regulating metal–organic frameworks as stationary phases and absorbents for analytical separations

Metal–organic frameworks (MOFs) are highly ordered framework systems composed of metal centers and organic linkers formed through coordination bonds.

Graphical abstract: Regulating metal–organic frameworks as stationary phases and absorbents for analytical separations
From the themed collection: Analytical Methods HOT Articles 2021
Communication

A nickel hydroxide platform prepared on a hydroxyl-enriched screen-printed carbon electrode for oxidative electrocatalysis

We report here the preparation of an activation-free Ni electrode through enrichment of hydroxyl functional groups via a base-catalyzed hydrolysis reaction on a “preanodized” screen printed carbon electrode.

Graphical abstract: A nickel hydroxide platform prepared on a hydroxyl-enriched screen-printed carbon electrode for oxidative electrocatalysis
From the themed collection: Analytical Methods HOT Articles 2021
Communication

Open port sampling interface mass spectrometry of wipe-based explosives, oxidizers, and narcotics for trace contraband detection

The solid–liquid extraction capabilities of open port sampling interface mass spectrometry enabled rapid and sensitive detection of military-grade explosives, homemade explosive oxidizers, and narcotics, critical to screening applications.

Graphical abstract: Open port sampling interface mass spectrometry of wipe-based explosives, oxidizers, and narcotics for trace contraband detection
From the themed collection: Analytical Methods HOT Articles 2021
Communication

A dual-channel Hill-type small-molecule pH probe

A Hill-type FRET-based ratiometric pH probe (PHHF) was designed and synthesized for sensitively detecting minor pH variations of lysosomes.

Graphical abstract: A dual-channel Hill-type small-molecule pH probe
From the themed collection: Analytical Methods HOT Articles 2021
Communication

Analysis of antioxidants in Chrysanthemum indici flos by online gradient extraction and HPLC-FRAP

Analysis of antioxidants in Chrysanthemum indici flos by online gradient extraction and HPLC-FRAP.

Graphical abstract: Analysis of antioxidants in Chrysanthemum indici flos by online gradient extraction and HPLC-FRAP
From the themed collection: Analytical Methods HOT Articles 2021
Communication

Simple mercury determination using an enclosed quartz cell with cold vapour-atomic absorption spectrometry

A simple method for determining total inorganic mercury (Hg) in solution using an enclosed quartz cell applying cold vapour-atomic absorption spectrometry (CV-AAS) can reduce sample volume, reductant, and cost compared with those of official methods.

Graphical abstract: Simple mercury determination using an enclosed quartz cell with cold vapour-atomic absorption spectrometry
From the themed collection: Analytical Methods HOT Articles 2021
Paper

A mitochondrial and lysosomal targeted ratiometric probe for detecting intracellular H2S

A dual-wavelength excitation ratiometric fluorescent probe, HABA, was prepared to detect H2S. HABA had excellent localization abilities toward mitochondria and lysosomes. HABA can not only detect exogenous H2S, but it can also detect endogenous H2S.

Graphical abstract: A mitochondrial and lysosomal targeted ratiometric probe for detecting intracellular H2S
From the themed collection: Analytical Methods HOT Articles 2021
Paper

A dual-channel colorimetric and fluorescent sensor for the rapid and ultrasensitive detection of kanamycin based on gold nanoparticles-copper nanoclusters

The assay based on Au NPs-Cu NCs showed selective response toward kanamycin within 2 minutes with a low LOD of 1.9/1.2 nM. The sensor possesses good reliability and accuracy, and can be applied for kanamycin detection in environmental water samples.

Graphical abstract: A dual-channel colorimetric and fluorescent sensor for the rapid and ultrasensitive detection of kanamycin based on gold nanoparticles-copper nanoclusters
From the themed collection: Analytical Methods HOT Articles 2021
Paper

Highly sensitive microRNA detection by a duplex-specific nuclease amplification triggered three-dimensional DNA machine

A dual signal amplification method has been developed for direct miRNA detection by combining the duplex-specific nuclease (DSN)-assisted recycling amplification and the nicking enzyme (NEase)-powered three dimensional (3D) DNA walker.

Graphical abstract: Highly sensitive microRNA detection by a duplex-specific nuclease amplification triggered three-dimensional DNA machine
From the themed collection: Analytical Methods HOT Articles 2021
Paper

Fabrication of a 2D metal–organic framework (MOF) nanosheet colloidal system and investigation of its fluorescence response to pesticide molecules

A novel Zn-LMOF was synthesized and exfoliated into ultrathin nanosheets to construct a stable sol–gel sensing system. It can sensitively sense pesticides such as imidacloprid, nitenpyram and dinotefuran via fluorescence quenching effect with very low detection limit (LOD).

Graphical abstract: Fabrication of a 2D metal–organic framework (MOF) nanosheet colloidal system and investigation of its fluorescence response to pesticide molecules
From the themed collection: Analytical Methods HOT Articles 2021
Paper

The systematic characterization of multiple components and metabolic profiling of bioactive constituents in Yaobitong capsule by UHPLC/Q-TOF-MS/MS

A rapid and reliable UHPLC-Q-TOF-MS/MS method was successfully established to analyze the complex compounds in Yaobitong capsule and analyze their absorption states in biological samples, including urine, feces, and bile, after the oral administration of Yaobitong capsule.

Graphical abstract: The systematic characterization of multiple components and metabolic profiling of bioactive constituents in Yaobitong capsule by UHPLC/Q-TOF-MS/MS
From the themed collection: Analytical Methods HOT Articles 2021
Paper

Photophysics of faecal pigments stercobilin and urobilin in aliphatic alcohols: introduction of a sensitive method for their detection using solvent phase extraction and fluorometry

Extraction based fluorometric method for high sensitive faecal pigment detection.

Graphical abstract: Photophysics of faecal pigments stercobilin and urobilin in aliphatic alcohols: introduction of a sensitive method for their detection using solvent phase extraction and fluorometry
From the themed collection: #RSCPoster Conference
Paper

Fast and quantitative analysis of level 3 details for latent fingerprints

Level 3 details play essential roles in practical latent fingerprint (LFP) identification.

Graphical abstract: Fast and quantitative analysis of level 3 details for latent fingerprints
From the themed collection: Analytical Methods HOT Articles 2021
Paper

Simultaneous extraction and surface enhanced Raman spectroscopy detection for the rapid and reliable identification of nicotine released from snus products

Here, simultaneous extraction and SERS detection of nicotine for rapid and reliable identification of nicotine release of snus products were performed based on nano-Au assembly hierarchy structure in the capillary.

Graphical abstract: Simultaneous extraction and surface enhanced Raman spectroscopy detection for the rapid and reliable identification of nicotine released from snus products
From the themed collection: Analytical Methods HOT Articles 2021
Paper

A direct competitive nanozyme-linked immunosorbent assay based on MnO2 nanosheets as a catalytic label for the determination of fumonisin B1

A direct competitive nanozyme-linked immunosorbent assay (dcNLISA) based on MnO2 nanosheets (MnO2 NSs) as a nanozyme label was developed for the highly sensitive determination of fumonisin B1 (FB1).

Graphical abstract: A direct competitive nanozyme-linked immunosorbent assay based on MnO2 nanosheets as a catalytic label for the determination of fumonisin B1
From the themed collection: Analytical Methods HOT Articles 2021
Paper

Development of an eco-friendly sample preparation protocol for metal determination in food samples: an oxygen pressurized single reaction chamber using diluted nitric acid

A single reaction chamber microwave-assisted wet digestion system using O2 as an auxiliary reagent and diluted HNO3 for multisample digestion and metal determination.

Graphical abstract: Development of an eco-friendly sample preparation protocol for metal determination in food samples: an oxygen pressurized single reaction chamber using diluted nitric acid
Paper

Optimizing the quantitative analysis of solid biomass fuel properties using laser induced breakdown spectroscopy (LIBS) coupled with a kernel partial least squares (KPLS) model

A KPLS method combined with LIBS data reflects the non-linear relationships between LIBS spectra and the fuel property index being predicted.

Graphical abstract: Optimizing the quantitative analysis of solid biomass fuel properties using laser induced breakdown spectroscopy (LIBS) coupled with a kernel partial least squares (KPLS) model
From the themed collection: Analytical Methods HOT Articles 2021
Paper

UPLC-Q-TOF-MS based metabolomics study of hawthorn leaves in different geographical regions

The quality evaluation of hawthorn leaves in different geographical regions derived from the dried leaves of Crataegus pinnatifida Bge.

Graphical abstract: UPLC-Q-TOF-MS based metabolomics study of hawthorn leaves in different geographical regions
From the themed collection: Analytical Methods HOT Articles 2021
Paper

Direct analysis of naphthenic acids in produced water and crude oil by NH2-surface-modified wooden-tip electrospray ionization mass spectrometry

An NH2-surface-coated wooden-tip electrospray ionization mass spectrometry method was developed for naphthenic acid analysis in water samples.

Graphical abstract: Direct analysis of naphthenic acids in produced water and crude oil by NH2-surface-modified wooden-tip electrospray ionization mass spectrometry
Paper

Non-invasive diagnosis of Crohn's disease based on SERS combined with PCA-SVM

The metabolic change of patients (Crohn's disease (CD)/active CD (aCD)/inactive CD (iCD)) and healthy controls (HC) could be identified by measuring urine with surface-enhanced Raman spectroscopy (SERS).

Graphical abstract: Non-invasive diagnosis of Crohn's disease based on SERS combined with PCA-SVM
From the themed collection: Analytical Methods HOT Articles 2021
Paper

Graphene oxide/perylene–aniline electrochemiluminescence platform for protein detection based on molecule recognition

FA-Poly-dA-ssDNA was attached to the 673 nm-dominated ECL nanomaterial GO/PTCDA-An to fabricate nuclease-free ultrasensitive FR sensors.

Graphical abstract: Graphene oxide/perylene–aniline electrochemiluminescence platform for protein detection based on molecule recognition
From the themed collection: Analytical Methods HOT Articles 2021
Paper

A highly emissive Zn(II)-pyridyl-benzimidazolyl-phenolato-based chemosensor: detection of H2PO4via “use” and “throw” device fabrication

A highly emissive Zn(II)-pyridyl-benzimidazolyl-phenolato-based chemosensor is used in the solution-state and cost-effective ‘on-site’ solid-state contact mode detection of H2PO4.

Graphical abstract: A highly emissive Zn(ii)-pyridyl-benzimidazolyl-phenolato-based chemosensor: detection of H2PO4−via “use” and “throw” device fabrication
From the themed collection: Analytical Methods HOT Articles 2021
Paper

A photoelectrochemical biosensor based on SnO2 nanoparticles for phosphatidylcholine detection in soybean oil

A novel photoelectrochemical biosensor based on SnO2 nanoparticles was developed for detection of phosphatidylcholine in soybean oil.

Graphical abstract: A photoelectrochemical biosensor based on SnO2 nanoparticles for phosphatidylcholine detection in soybean oil
From the themed collection: Analytical Methods HOT Articles 2021
Paper

Development and validation of a high-performance liquid chromatography method for levothyroxine sodium quantification in plasma for pre-clinical evaluation of long-acting drug delivery systems

New HPLC method to quantify levothyroxine in plasma samples was developed as per ICH and FDA, and was successfully applied in the determination of pharmacokinetic profiles after the administration of long-acting delivery systems in rats.

Graphical abstract: Development and validation of a high-performance liquid chromatography method for levothyroxine sodium quantification in plasma for pre-clinical evaluation of long-acting drug delivery systems
From the themed collection: Analytical Methods HOT Articles 2021
Paper

Biomimetic self-assembly of lipase-zeolitic imidazolate frameworks with enhanced biosensing of protox inhibiting herbicides

Protox inhibiting herbicides such as nitrofen have detrimental effects on the environment and human health.

Graphical abstract: Biomimetic self-assembly of lipase-zeolitic imidazolate frameworks with enhanced biosensing of protox inhibiting herbicides
From the themed collection: Analytical Methods HOT Articles 2021
Paper

A full spectral analysis method for the gamma spectrum: weighted library least squares

An algebraic weighted library least squares method for gamma spectrum analysis is proven to make the analytical results more stable.

Graphical abstract: A full spectral analysis method for the gamma spectrum: weighted library least squares
From the themed collection: Analytical Methods HOT Articles 2021
Paper

Application of new N- and S-doped amorphous carbon in D-μSPE and its combination with deep eutectic solvent-based DLLME for the extraction of some mycotoxins from soymilk

A new amorphous carbon-based dispersive micro solid-phase extraction method was developed for the extraction and preconcentration of several mycotoxins from soymilk samples.

Graphical abstract: Application of new N- and S-doped amorphous carbon in D-μSPE and its combination with deep eutectic solvent-based DLLME for the extraction of some mycotoxins from soymilk
From the themed collection: Analytical Methods HOT Articles 2021
Open Access Paper

Smartphone-based colorimetric detection system for portable health tracking

The use of colorimetric sensors is encouraged by their simple operation, but limited by the lack of standardization. This article reports on a smartphone application to precisely readout urine strips via color mapping and RGB-to-HSV transposition.

Graphical abstract: Smartphone-based colorimetric detection system for portable health tracking
From the themed collection: Analytical Methods HOT Articles 2021
Open Access Paper

Detection of glyphosate with a copper(II)-pyrocatechol violet based GlyPKit

This paper describes the development of a test kit for the naked-eye detection of glyphosate (GlyP) using a copper(II)-pyrocatechol violet complex immobilized on a C18 solid support.

Graphical abstract: Detection of glyphosate with a copper(ii)-pyrocatechol violet based GlyPKit
From the themed collection: Analytical Methods HOT Articles 2021
Paper

Thiol-mediated etching of gold nanorods as a neoteric strategy for room-temperature and multicolor detection of nitrite and nitrate

Thiourea as a sulfur-containing compound accelerates the etching rate of gold nanorods (AuNRs) leading to a wide color change from brown to light brown, green, blue, purple, pink, and colorless.

Graphical abstract: Thiol-mediated etching of gold nanorods as a neoteric strategy for room-temperature and multicolor detection of nitrite and nitrate
From the themed collection: Analytical Methods HOT Articles 2021
Paper

A novel approach to detect barium in gunshot residue using a handheld device: a forensic application

The aim of the study is to develop a handheld device based on the colorimetric detection of Ba2+ metal in gunshot residue using gold nanoparticles capped with sodium malonate with great sensitivity and selectivity.

Graphical abstract: A novel approach to detect barium in gunshot residue using a handheld device: a forensic application
From the themed collection: Analytical Methods HOT Articles 2021
Paper

Detection of hydrogen peroxide and glucose with a novel fluorescent probe by the enzymatic reaction of amino functionalized MOF nanosheets

The mechanism for detecting H2O2 and glucose in the system of the NH2-MIL-53(Al)-HRP enzymatic reaction.

Graphical abstract: Detection of hydrogen peroxide and glucose with a novel fluorescent probe by the enzymatic reaction of amino functionalized MOF nanosheets
From the themed collection: Analytical Methods HOT Articles 2021
Paper

Sensitive osteosarcoma diagnosis through five-base telomerase product-triggered CRISPR-Cas12a enhanced rolling circle amplification

CRISPR-Cas12a assisted rolling circle amplification for sensitive osteosarcoma diagnosis.

Graphical abstract: Sensitive osteosarcoma diagnosis through five-base telomerase product-triggered CRISPR-Cas12a enhanced rolling circle amplification
From the themed collection: Analytical Methods HOT Articles 2021
Paper

Affiblot: a dot blot-based screening device for selection of reliable antibodies

A report on a palm-sized dot blot-based device that allows simultaneous semi-quantitative comparison of up to five antibodies from different suppliers regarding their affinity/avidity, cross-reactivity, and batch-to-batch reliability.

Graphical abstract: Affiblot: a dot blot-based screening device for selection of reliable antibodies
From the themed collection: Analytical Methods HOT Articles 2021
Paper

A novel fluorescent probe based on a triphenylamine derivative for the detection of HSO3 with high sensitivity and selectivity

The probe has excellent sensitivity, fast response and low limit of detection to HSO3. The mechanism was verified by density functional theory (DFT) and time-dependent DFT. The sensor has been successfully imaged in RAW264.7 cells.

Graphical abstract: A novel fluorescent probe based on a triphenylamine derivative for the detection of HSO3− with high sensitivity and selectivity
From the themed collection: Analytical Methods HOT Articles 2021
Paper

Simulation and machine learning modelling based comparative study of InAlGaN and AlGaN high electron mobility transistors for the detection of HER-2

For the first time, a InAlGaN based HEMT has been used for biosensing applications. Also, machine learning techniques are introduced in the modelling of the physics of a semiconductor device.

Graphical abstract: Simulation and machine learning modelling based comparative study of InAlGaN and AlGaN high electron mobility transistors for the detection of HER-2
From the themed collection: Analytical Methods HOT Articles 2021
Paper

Quantitative and specific detection of viable pathogens on a portable microfluidic chip system by combining improved propidium monoazide (PMAxx) and loop-mediated isothermal amplification (LAMP)

Improved propidium monoazide (PMAxx) and loop-mediated isothermal amplification (LAMP) were used to distinguish between viable and dead C. albicans. A portable microfluidic chip system was developed to detect multiple viable pathogens in parallel.

Graphical abstract: Quantitative and specific detection of viable pathogens on a portable microfluidic chip system by combining improved propidium monoazide (PMAxx) and loop-mediated isothermal amplification (LAMP)
From the themed collection: Analytical Methods HOT Articles 2021
Paper

Lysosome targeting, Cr(VI) and L-AA sensing, and cell imaging based on N-doped blue-fluorescence carbon dots

N-doped blue-fluorescence carbon dots (N-CDs) were fabricated via a one-pot hydrothermal method using folic acid and p-phenylenediamine.

Graphical abstract: Lysosome targeting, Cr(vi) and l-AA sensing, and cell imaging based on N-doped blue-fluorescence carbon dots
From the themed collection: Analytical Methods HOT Articles 2021
Paper

The evaluation of the chemical quality and UV overall components dissolution consistency of Flos Chrysanthemi Indici preparation

Integrating capillary electrophoresis fingerprints and UV overall components dissolution consistency to give the overall quality control of Flos Chrysanthemi Indici preparation.

Graphical abstract: The evaluation of the chemical quality and UV overall components dissolution consistency of Flos Chrysanthemi Indici preparation
From the themed collection: Analytical Methods HOT Articles 2021
Paper

Rapid quantitative analysis of trace elements in plutonium alloys using a handheld laser-induced breakdown spectroscopy (LIBS) device coupled with chemometrics and machine learning

We present the first reported quantification of trace elements in plutonium via a portable laser-induced breakdown spectroscopy (LIBS) device and demonstrate the use of chemometric analysis to enhance the handheld device's sensitivity and precision.

Graphical abstract: Rapid quantitative analysis of trace elements in plutonium alloys using a handheld laser-induced breakdown spectroscopy (LIBS) device coupled with chemometrics and machine learning
From the themed collection: Analytical Methods HOT Articles 2021
Paper

An ultrasensitive homogeneous electrochemical biosensor based on CRISPR-Cas12a

A simple and immobilization-free homogeneous electrochemical biosensor for the detection of human papillomavirus (HPV-16) has been fabricated by combining with methylene blue (MB)-labeled probes toward the negatively-charged indium tin oxide (ITO) electrode.

Graphical abstract: An ultrasensitive homogeneous electrochemical biosensor based on CRISPR-Cas12a
From the themed collection: Analytical Methods HOT Articles 2021
Paper

Thermo-sensitivity of hybrid nanogels for specific endogenous hydrogen sulfide detection and efficient flash chill treatment

Thermo-responsive nanogels, poly(NIPAM–AAM) were prepared by a facile method of free radical one-pot precipitation based on monomeric N-isopropylacrylamide (NIPAM).

Graphical abstract: Thermo-sensitivity of hybrid nanogels for specific endogenous hydrogen sulfide detection and efficient flash chill treatment
From the themed collection: Analytical Methods HOT Articles 2021
Paper

An integrating strategy for serum metabolomics and microarray analysis to expand the understanding of diet-induced obesity

Obesity is a key component of metabolic syndrome and is precipitated by complex interactions between multiple environmental and genetic factors.

Graphical abstract: An integrating strategy for serum metabolomics and microarray analysis to expand the understanding of diet-induced obesity
From the themed collection: Analytical Methods HOT Articles 2021
Open Access Paper

Detection of organic and inorganic gunshot residues from hands using complexing agents and LC-MS/MS

LC-MS/MS and guest-host chemistry is a viable approach for the dual detection of organic and inorganic gunshot residue.

Graphical abstract: Detection of organic and inorganic gunshot residues from hands using complexing agents and LC-MS/MS
From the themed collection: Analytical Methods HOT Articles 2021
Paper

Ultrasensitive immunochromatographic strip for the detection of cyhalothrin in foods

A quantitative immunochromatographic strip assay has been developed for rapid screening of lambda-cyhalothrin in foods.

Graphical abstract: Ultrasensitive immunochromatographic strip for the detection of cyhalothrin in foods
From the themed collection: Analytical Methods HOT Articles 2021
Paper

Three asymmetric BODIPY derivatives as fluorescent probes for highly selective and sensitive detection of cysteine in living cells

Three new asymmetric BODIPY-based fluorescent probes were designed and synthesized for highly selective and sensitive detection of cysteine. These probes were able to image exogenous and endogenous Cys through green or red channels in living cells.

Graphical abstract: Three asymmetric BODIPY derivatives as fluorescent probes for highly selective and sensitive detection of cysteine in living cells
From the themed collection: Analytical Methods HOT Articles 2021
Paper

Rapid and sensitive detection of Staphylococcus aureus and Klebsiella pneumonia based on bacitracin-modified Fe3O4@PDA magnetic beads combined with matrix-assisted laser desorption ionization-time of flight mass spectrometry

Bacitracin was immobilized on the surface of Fe3O4@PDA magnetic nanoparticles for the rapid enrichment and sensitive detection of Staphylococcus aureus (G+) and Klebsiella pneumoniae (G) in biological samples combined with MALDI-TOF MS.

Graphical abstract: Rapid and sensitive detection of Staphylococcus aureus and Klebsiella pneumonia based on bacitracin-modified Fe3O4@PDA magnetic beads combined with matrix-assisted laser desorption ionization-time of flight mass spectrometry
From the themed collection: Analytical Methods HOT Articles 2021
Paper

A new method for cartap detection with high sensitivity and selectivity based on the inner filter effect between GSH-Cu NCs and Au NPs

A schematic diagram of sensing cartap using the IFE between GSH-Cu NCs and Au NPs.

Graphical abstract: A new method for cartap detection with high sensitivity and selectivity based on the inner filter effect between GSH-Cu NCs and Au NPs
From the themed collection: Analytical Methods HOT Articles 2021
Open Access Paper

A multi-residue chiral liquid chromatography coupled with tandem mass spectrometry method for analysis of antifungal agents and their metabolites in aqueous environmental matrices

A new analytical method for combined separation of chiral and chiral antifungal agents in the environment has been developed.

Graphical abstract: A multi-residue chiral liquid chromatography coupled with tandem mass spectrometry method for analysis of antifungal agents and their metabolites in aqueous environmental matrices
From the themed collection: Analytical Methods HOT Articles 2021
Paper

Nanobiosensing based on optically selected antibodies and superparamagnetic labels for rapid and highly sensitive quantification of polyvalent hepatitis B surface antigen

Magnetic LF assay for rapid quantification of HBsAg in serum.

Graphical abstract: Nanobiosensing based on optically selected antibodies and superparamagnetic labels for rapid and highly sensitive quantification of polyvalent hepatitis B surface antigen
From the themed collection: Analytical Methods HOT Articles 2021
Paper

Fluorometric discrimination of tyrosine isomers based on the inner filter effect of chiral Au nanoparticles on MoS2 quantum dots

A sensitive fluorescent chiral sensor is developed based on the inner filter effect of chiral Au nanoparticles on MoS2 quantum dots, which can be used for the discrimination of tyrosine isomers.

Graphical abstract: Fluorometric discrimination of tyrosine isomers based on the inner filter effect of chiral Au nanoparticles on MoS2 quantum dots
From the themed collection: Analytical Methods HOT Articles 2021
Paper

The development of an endoplasmic reticulum-targeting fluorescent probe for the imaging of 1,4-dithiothreitol (DTT) in living cells

An effective turn-on ER-targeting fluorescent probe ER-DTT was designed to image DTT of endoplasmic reticulum for the first time.

Graphical abstract: The development of an endoplasmic reticulum-targeting fluorescent probe for the imaging of 1,4-dithiothreitol (DTT) in living cells
From the themed collection: Analytical Methods HOT Articles 2021
Paper

Highly selective and rapid detection of silver ions by using a “turn on” non-fluorescent cysteine stabilized gold nanocluster probe

Highly selective and rapid detection of silver ions by using a “turn on” non-fluorescent gold nanocluster probe.

Graphical abstract: Highly selective and rapid detection of silver ions by using a “turn on” non-fluorescent cysteine stabilized gold nanocluster probe
From the themed collection: Analytical Methods HOT Articles 2021
Paper

A substantial increase of analytical throughput in capillary electrophoresis throughput by separation-interrupted sequential injections

We proposed an idea of separation-interrupted sequential injections (Sisi) to substantially increase the throughput of CE together with theory and experimental demonstration. The separation time of Sisi-CE-C4D/C4D is only 21% of that of normal CE.

Graphical abstract: A substantial increase of analytical throughput in capillary electrophoresis throughput by separation-interrupted sequential injections
From the themed collection: Analytical Methods HOT Articles 2021
Paper

A novel ratiometric fluorescent probe from a hemicyanine derivative for detecting NAD(P)H in a cell microenvironment

In this paper, a ratiometric fluorescent probe for NAD(P)H derived from coumarin and hemicyanine was synthesized. The ratiometric fluorescent probe provided an important theoretical basis for sensing NAD(P)H.

Graphical abstract: A novel ratiometric fluorescent probe from a hemicyanine derivative for detecting NAD(P)H in a cell microenvironment
From the themed collection: Analytical Methods HOT Articles 2021
Paper

Simultaneous immunodetection of ionophore antibiotics, salinomycin and narasin, in poultry products and milk

Immunoassay of ionophore antibiotics, salinomycin and narasin, was first developed for milk analysis. Good recovery was promoted by the absence of Na+–K+ ions in tested samples.

Graphical abstract: Simultaneous immunodetection of ionophore antibiotics, salinomycin and narasin, in poultry products and milk
From the themed collection: Analytical Methods HOT Articles 2021
Paper

Simple chemical detection based on a surface-modified electroosmotic pump via interval immobilization

Environmental water quality monitoring plays an important role in human health risk assessments for pharmaceuticals in water and pollutant source control.

Graphical abstract: Simple chemical detection based on a surface-modified electroosmotic pump via interval immobilization
From the themed collection: Analytical Methods HOT Articles 2021
Paper

Developing in vitro models to assess fish gill excretion of emerging contaminants

In vitro fish gill model to study the branchial efflux of emerging contaminants at ever lower concentrations in freshwater.

Graphical abstract: Developing in vitro models to assess fish gill excretion of emerging contaminants
From the themed collection: Analytical Methods HOT Articles 2021
Paper

Homo-FRET enhanced ratiometric fluorescence strategy for exonuclease III activity detection

A homo-FRET enhanced ratiometric fluorescence method has been developed successfully for the detection of Exo III activity.

Graphical abstract: Homo-FRET enhanced ratiometric fluorescence strategy for exonuclease III activity detection
From the themed collection: Analytical Methods HOT Articles 2021
Paper

A novel all-3D-printed thread-based microfluidic device with an embedded electrochemical detector: first application in environmental analysis of nitrite

A fully 3D-printed microfluidic thread-based device containing an embedded electrochemical detector is first reported. A green method based on microflow injection analysis for sensing of nitrite ions in environmental samples is also first presented.

Graphical abstract: A novel all-3D-printed thread-based microfluidic device with an embedded electrochemical detector: first application in environmental analysis of nitrite
Paper

Theoretical and experimental verification of imaging resolution factors in scanning electrochemical microscopy

The mathematical expression for the real-time current of the SECM tip and the imaging resolution has been derived, which revealed the effects of tip electrode size and tip–substrate distance on imaging resolution.

Graphical abstract: Theoretical and experimental verification of imaging resolution factors in scanning electrochemical microscopy
From the themed collection: Analytical Methods HOT Articles 2021
Paper

The extraction of phenolic acids and polysaccharides from Lilium lancifolium Thunb. using a deep eutectic solvent

This study provided a new application of deep eutectic solvents (DESs) in the simultaneous extraction of phenolic acids and polysaccharides from the bulbs of Lilium lancifolium Thunb.

Graphical abstract: The extraction of phenolic acids and polysaccharides from Lilium lancifolium Thunb. using a deep eutectic solvent
From the themed collection: Analytical Methods HOT Articles 2021
Paper

Preparative separation of seven polyphenols from Perillae Folium via pH-zone-refining counter-current chromatography combined with high-speed counter-current chromatography

A separation method using pH-ZRCCC combined with HSCCC was proposed to separate the crude sample of Perillae Folium with different constituents and polarity, and three phenolic acids and four flavonoid glycosides were isolated successfully.

Graphical abstract: Preparative separation of seven polyphenols from Perillae Folium via pH-zone-refining counter-current chromatography combined with high-speed counter-current chromatography
From the themed collection: Analytical Methods HOT Articles 2021
81 items - Showing page 1 of 2

About this collection

This themed collection features articles published in Analytical Methods marked as HOT by the handling editor or as recommended by referees. Congratulations to all the authors whose articles are featured.

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