Light-responsive nanozymes for biosensing
Using light as an external stimulus plays a key role not only in modulating activities of nanozymes, but also in constructing efficient biosensing systems.
Nanomaterial-Based Multiplex Optical Sensors
Recent advances in boronic acid-based optical chemosensors
This minireview highlights the developments in optical chemosensors from 2014 to 2016 that utilise the boronic acid interaction with polyols or Lewis bases.
Single plasmonic nanoparticles as ultrasensitive sensors
In this mini review, we will provide a brief introduction focusing on the current applications of single plasmonic nanoparticle-based sensors using DFM, including the detection of molecules, the real-time monitoring of chemical/electrochemical reactions and the imaging of living cells.
Recent advances of plasmonic nanoparticle-based optical analysis in homogeneous solution and at the single-nanoparticle level
Ionophore-based pH independent detection of ions utilizing aggregation-induced effects
Here, aggregation-induced emission and quenching were incorporated for the first time in ionophore-based optical nanosensors.
Widefield frequency domain fluorescence lifetime imaging microscopy (FD-FLIM) for accurate measurement of oxygen gradients within microfluidic devices
A widefield FD-FLIM system with fast acquisition speed is utilized to accurately characterize oxygen gradient distributions within microfluidic devices.
A novel turn-on fluorescent probe for selective sensing and imaging of glutathione in live cells and organisms
A novel 1-oxo-1H-phenalene-2,3-dicarbonitrile (OPD)-based fluorescent probe was developed to sense and image GSH in HeLa cells, different imatinib-resistant K562 cells, D. magna and zebrafish embryos.
Excitation-independent emission carbon nanoribbon polymer as a ratiometric photoluminescent probe for highly selective and sensitive detection of quercetin
In this study, sulfur–nitrogen co-doped carbon nanoribbon (SNCNR) polymers with stable dual-emission fluorescence were synthesized using a one-step traditional hydrothermal method of 6-mercaptopurine in an aqueous methanol solution.
A novel fluorescent sensing platform based on metal-polydopamine frameworks for the dual detection of kanamycin and oxytetracycline
In this study, we report the dual detection of kanamycin (KMY) and oxytetracycline (OTC) using metal polydopamine frameworks (MPDA) for the first time.
Detection of sulfadimethoxine using optical images of liquid crystals
An aptamer based liquid crystal biosensor was firstly developed for sulfadimethoxine detection achieving a lower detection limit of 10 μg L−1.
Reversible fluorescence modulation of BSA stabilised copper nanoclusters for the selective detection of protamine and heparin
Depicting fluorescence sensing of protamine and heparin based on aggregation and disaggregation of copper nanoclusters.
Electrogenerated chemiluminescence of black phosphorus nanosheets and its application in the detection of H2O2
Black phosphorus nanosheets (BPNS) were synthesized from BP crystals through liquid exfoliation coupled with ultrasonic methods under aqueous conditions.
Facile fabrication of fluorescent Fe-doped carbon quantum dots for dopamine sensing and bioimaging application
A facile Fe-doped carbon quantum dot based fluorescent sensor for dopamine sensing and bioimaging was constructed.
Transition metal-coordinated graphitic carbon nitride dots as a sensitive and facile fluorescent probe for β-amyloid peptide detection
Herein, we developed a sensitive graphitic carbon nitride quantum dot (gCNQD)-based fluorescent strategy for β-amyloid peptide monomer (Aβ) determination down to the ng mL−1 level for the first time.
Thiol–ene click reaction-induced fluorescence enhancement by altering the radiative rate for assaying butyrylcholinesterase activity
A fluorescent molecular probe for assaying BChE activity based on thiol-triggered fluorescence enhancement via a thiol–ene click reaction was developed.
A highly selective naphthalimide-based ratiometric fluorescent probe for the recognition of tyrosinase and cellular imaging
Upon the addition of tyrosinase to the probe solution, the monophenolic unit is oxidized to o-dihydroxy and consequently releases the 4-aminonaphthalimide unit.
A fluorescent sensor based on aggregation-induced emission: highly sensitive detection of hydrazine and its application in living cell imaging
A fluorescent sensor based on aggregation-induced emission for amines was prepared and its highly sensitive detection of hydrazine and application in living cell imaging were investigated in detail.
A rainbow ratiometric fluorescent sensor array on bacterial nanocellulose for visual discrimination of biothiols
The crucial role of biothiols in many biological processes, which turns them into important biomarkers for the early diagnosis of various diseases, the development of an affordable, sensitive and portable probe for the detection and discrimination of these compounds is of great importance.
MoS2 nanohybrid as a fluorescence sensor for highly selective detection of dopamine
A simple and facile strategy is developed for the selective and sensitive detection of dopamine, using luminescent MoS2 nanohybrid particles.
A tri-site fluorescent probe for simultaneous sensing of hydrogen sulfide and glutathione and its bioimaging applications
Hydrogen sulfide (H2S) and biothiol molecules, such as glutathione (GSH), cysteine (Cys), and homocysteine (Hcy), play an important role in biology.
A ratiometric fluorogenic probe for the real-time detection of SO32− in aqueous medium: application in a cellulose paper based device and potential to sense SO32− in mitochondria
A new water soluble and fluorogenic probe (L) that can demonstrate the specific ratiometric detection of a SO2 derivative (SO32−) in 100% aqueous medium and live cells has been designed and synthesized.
Functionalized gold nanoparticle-enhanced competitive assay for sensitive small-molecule metabolite detection using surface plasmon resonance
A functionalized gold nanoparticle-enhanced competitive assay was developed to overcome the sensitivity challenge associated with direct SPR sensing of small-molecule metabolites.
Excellent peroxidase mimicking property of CuO/Pt nanocomposites and their application as an ascorbic acid sensor
Functional CuO/Pt nanocomposites were successfully constructed as peroxidase mimics for highly selective colorimetric detection of ascorbic acid.
An ultrasensitive multi-walled carbon nanotube–platinum–luminol nanocomposite-based electrochemiluminescence immunosensor
An ultrasensitive electrochemiluminescence (ECL) immunosensor for carbohydrate antigen 19-9 (CA19-9) detection using multi-walled carbon nanotube–platinum–luminol nanocomposites (MWCNT–Pt–luminol) as nanointerface and signal tags was designed.
About this collection
A collection of papers and reviews on optical biosensor devices. Optical biosensors are based on the signal changes in UV/Vis and Infrared absorptions, fluorescence/luminescence emission or light scattering when chemical or biological reactions occur. Sensor devices such as lateral flow assay strips, microfluidic channels or microarrays are essential for miniaturised biosensor constructions. This collection covers recent developments in various sensor devices, combined with diverse optical detection methods.
This collection is guest edited by Analytical Methods Associate Editors’ Ryan Bailey (University of Michigan, USA), Jaebum Choo (Chung-Ang University, South Korea), Laura Lechuga (Catalan Institute of Nanoscience and Nanotechnology, Spain), Baohong Liu (Fudan University), and Advisory Board member Chaoyong James Yang (Xiamen University, China).