Open Access Article
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Expression of concern: Ingestion of Bifidobacterium longum subspecies infantis strain CCFM687 regulated emotional behavior and the central BDNF pathway in chronic stress-induced depressive mice through reshaping the gut microbiota
Peijun
Tian
ab,
Renying
Zou
ab,
Linhong
Song
cd,
Xu
Zhang
cd,
Bin
Jiang
cd,
Gang
Wang
*abef,
Yuan-kun
Lee
g,
Jianxin
Zhao
abf,
Hao
Zhang
abfhi and
Wei
Chen
abhj
aState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi 214122, P. R. China
bSchool of Food Science and Technology, Jiangnan University, Wuxi 214122, P. R. China. E-mail: wanggang@jiangnan.edu.cn; Fax: +(86)510-85912155; Tel: +(86)510-85912155
cState Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics, Wuhan National Laboratory for Optoelectronics, National Center for Magnetic Resonance in Wuhan, Key Laboratory of Magnetic Resonance in Biological Systems, Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences, Wuhan, China
dUniversity of Chinese Academy of Sciences, Beijing, China
eInternational Joint Research Laboratory for Probiotics, Jiangnan University, Wuxi 214122, P. R. China
f(Yangzhou) Institute of Food Biotechnology, Jiangnan University, Yangzhou 225004, P. R. China
gDepartment of Microbiology & Immunology, National University of Singapore, Singapore 117597
hNational Engineering Research Center for Functional Food, Jiangnan University, Wuxi 214122, P. R. China
iWuxi Translational Medicine Research Center and Jiangsu Translational Medicine Research Institute Wuxi Branch, Wuxi 214122, P. R. China
jBeijing Innovation Centre of Food Nutrition and Human Health, Beijing Technology and Business University (BTBU), Beijing 100048, P. R. China
First published on 13th November 2025
Abstract
Expression of concern for ‘Ingestion of Bifidobacterium longum subspecies infantis strain CCFM687 regulated emotional behavior and the central BDNF pathway in chronic stress-induced depressive mice through reshaping the gut microbiota’ by Peijun Tian et al., Food Funct., 2019, 10, 7588–7598, https://doi.org/10.1039/C9FO01630A.
The Royal Society of Chemistry is publishing this expression of concern in order to alert readers that concerns have been raised regarding the suitability of the primers used in this study, which might affect the reliability of the data. An investigation is underway and an expression of concern will continue to be associated with the article until we receive conclusive evidence regarding the reliability of the reported data.
Philippa Ross
6th November 2025
Executive Editor, Food & Function
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