Open Access Article
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Expression of concern: An in vitro screening method for probiotics with antidepressant-like effect using the enterochromaffin cell model

Peijun Tian ab, Huiyue Zhu ab, Renying Zou ab, Qinming Kong ab, Mengshu Xu ab, Jianxin Zhao abcd, Hao Zhang abdef, Wei Chen abeg and Gang Wang *abcd
aState Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, China. E-mail: wanggang@jiangnan.edu.cn; Tel: (+86)510-85912155
bSchool of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu, China
cInternational Joint Research Center for Probiotics & Gut Health, Jiangnan University, Wuxi, Jiangsu, China
d(Yangzhou) Institute of Food Biotechnology, Jiangnan University, Yangzhou, Jiangsu, China
eNational Engineering Center of Functional Food, Jiangnan University, Wuxi, Jiangsu, China
fWuxi Translational Medicine Research Center and Jiangsu Translational Medicine Research Institute Wuxi Branch, Wuxi, P. R. China
gBeijing Innovation Centre of Food Nutrition and Human Health, Beijing Technology and Business University (BTBU), Beijing, China

Received 6th November 2025 , Accepted 6th November 2025

First published on 13th November 2025


Abstract

Expression of concern for ‘An in vitro screening method for probiotics with antidepressant-like effect using the enterochromaffin cell model’ by Peijun Tian et al., Food Funct., 2021, 12, 646–655, https://doi.org/10.1039/D0FO02307H.


The Royal Society of Chemistry is publishing this expression of concern in order to alert readers that concerns have been raised regarding the suitability of primers used in this study, which might affect the reliability of the data. An investigation is underway and an expression of concern will continue to be associated with the article until we receive conclusive evidence regarding the reliability of the reported data.

 

Philippa Ross

6th November 2025

Executive Editor, Food & Function


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