RSC Advances  

A Cur–PDA NP based nanoregulator was developed for targeting ferroptosis to mitigate neuron degeneration by regulating iron and ROS homeostasis, suppressing lipid peroxidation and oxidative stress, and improving mitochondrial function.

Alzheimer has many crucial factors that should be considered in order to get better results from clinical trials. Benzimidazole and its isosteres represent significant scaffolds for designing potential multi-target anti-alzheimer molecules.

Monoamine oxidases (MAOs) inhibitors could decrease reactive oxygen species (ROS) generation, enhance mono-aminergic neural transmission, and have major therapeutic benefits for the treatment of Alzheimer's disease (AD).

The Sn–I metabolite decreases the contractile response to KCl or phenylephrine (PE) mainly by blocking Ca²⁺ entry through voltage-gated Ca²⁺ channel (VGCC).

The new classification of APAP combinations (prodrugs, codrugs, and hybrids) was proposed. It makes a better understanding of the SAR studies for new pain relievers research and the design development for the analgesic APAP-based compounds.

Sulfobutylether β-cyclodextrin can significantly improve the antioxidant and antibacterial activities of quercetin through the formation of an inclusion complex, and their interactions have been elucidated.

4-Nonylphenol, an emerging endocrine disruptor, raises health concerns. Radiolabeling and in vivo tracing of 4NP reveal significant tissue accumulation, emphasizing intricate distribution and potential long-term effects for risk assessments.

Silica-coated lanthanide-doped upconverting nanoparticles (UCNPs) are internalized by mammalian cells. The bipyramidal UCNPs are non-toxic and elicit minor stress responses in a cell type-dependent fashion.

Recently, new pharmaceutical discoveries have become very important for addressing diverse health problems and protecting humanity.

Vinpocetine and Vincamine were extensively employed in the treatment of ischemic stroke, serving as effective cerebrovascular vasodilators.

Nowadays, several studies have highlighted the ability of snail mucus in maintaining healthy skin conditions due to its emollient, regenerative and protective properties.

Preparation of CTU microspheres and scheme of thrombolysis.

Depression is one of the most mutilating conditions in the world today.

S. tangutica extract was obtained by medium-pressure liquid chromatography and its activity studied using HPLC-DPPH screening.

Glycyrrhetinic acid, a triterpenoid compound primarily sourced from licorice root, as well as its derivatives produced through structural modification, exhibit noteworthy biological attributes, including anti-inflammatory, anti-tumor, antibacterial, antiviral, and antioxidant effects.

Deuterated proanthocyanidin metabolite 5-(3′,4′-dihydroxyphenyl)-γ-valerolactone has been successfully produced.

Shrimp oil (SO) nanoemulsions stabilized by fish myofibrillar protein, considered as functional foods, were prepared via microfluidization and ultrasonication.

Despite the advancements in cancer therapies during the past few years, chemo/photo resistance, severe toxic effects, recurrence of metastatic tumors, and non-selective targeting remain incomprehensible.

Through the hydrogen transfer reaction of adjacent hydroxyl groups, CQAs demonstrate excellent antioxidant activity in aqueous physiological environments.

Copper deficiency can trigger various diseases such as Amyotrophic Lateral Sclerosis (ALS), Parkinson's disease (PD) and even compromise the development of living beings, as manifested in Menkes disease (MS).

Ophioglossum vulgatum L. (O. vulgatum) is a species of fern used in traditional Chinese medicine, however, its application in cosmetics has not yet been studied.

Disease-modifying osteoarthritis drugs (DMOADs) are a new therapeutic class for osteoarthritis (OA) prevention or inhibition of the disease development.

To maintain the freshness of the fruit during storage, sodium alginate/carboxymethyl cellulose films embedded with pH-senstive liposomes encapsulated green tea extract were developed (SA/CMC/TP-Lip).

α-Lipoic acid (ALA) is a naturally occurring sulfur-containing fatty acid with high antioxidant activity.

Astaxanthin/kaempferol co-encapsulated nanoparticles were fabricated using cremophor RH40 and lecithin as surface-active agents, and β-cyclodextrin as an encapsulating agent. The nanoparticles showed high dispersibility and stability in aqueous solutions, which enhances their bioactivity.