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Themed collection Organ-, body- and disease-on-a-chip systems

10 items
Editorial

Organ-, body- and disease-on-a-chip systems

Thought leader Michael Shuler introduces the Lab on a Chip organ, body and disease on a chip thematic collection.

Graphical abstract: Organ-, body- and disease-on-a-chip systems
From the themed collection: Organ-, body- and disease-on-a-chip systems
Perspective

Organ-on-a-chip devices advance to market

We reviewed the foundational technologies underlying the commercialization efforts of the current prominent organ-on-a-chip start-ups.

Graphical abstract: Organ-on-a-chip devices advance to market
From the themed collection: Organ-, body- and disease-on-a-chip systems
Communication

“Open-top” microfluidic device for in vitro three-dimensional capillary beds

We introduce a novel microfluidic device to co-culture a blood vessel network and cell tissues in an in vivo-like niche.

Graphical abstract: “Open-top” microfluidic device for in vitro three-dimensional capillary beds
From the themed collection: Organ-, body- and disease-on-a-chip systems
Paper

Cardiac microphysiological devices with flexible thin-film sensors for higher-throughput drug screening

Contractility and rate of human stem cell heart tissues.

Graphical abstract: Cardiac microphysiological devices with flexible thin-film sensors for higher-throughput drug screening
From the themed collection: Organ-, body- and disease-on-a-chip systems
Open Access Paper

Mimicking arterial thrombosis in a 3D-printed microfluidic in vitro vascular model based on computed tomography angiography data

Studying blood clotting in stereolithography 3D-printed microfluidic chips with endothelialised vascular structures.

Graphical abstract: Mimicking arterial thrombosis in a 3D-printed microfluidic in vitro vascular model based on computed tomography angiography data
From the themed collection: Organ-, body- and disease-on-a-chip systems
Paper

Organs-on-Chips with combined multi-electrode array and transepithelial electrical resistance measurement capabilities

Combined integration of TEER and MEA sensors in a single endothelialized Organ-on-Chip platform.

Graphical abstract: Organs-on-Chips with combined multi-electrode array and transepithelial electrical resistance measurement capabilities
From the themed collection: Organ-, body- and disease-on-a-chip systems
Paper

Simultaneous electrical recording of cardiac electrophysiology and contraction on chip

We report a new heart-on-chip design capable of electrical stimulation, recording of growth, contraction and activating map from in vitro-cultured human cardiac tissues.

Graphical abstract: Simultaneous electrical recording of cardiac electrophysiology and contraction on chip
From the themed collection: Organ-, body- and disease-on-a-chip systems
Paper

A disease model of diabetic nephropathy in a glomerulus-on-a-chip microdevice

A biomimetic glomerulus-on-a-chip microdevice was created to recapitulate a disease model of diabetic nephropathy.

Graphical abstract: A disease model of diabetic nephropathy in a glomerulus-on-a-chip microdevice
From the themed collection: Organ-, body- and disease-on-a-chip systems
Paper

A vascularized and perfused organ-on-a-chip platform for large-scale drug screening applications

A vascularized, perfused organ-on-a-chip platform suitable for large-scale drug efficacy/toxicity screening.

Graphical abstract: A vascularized and perfused organ-on-a-chip platform for large-scale drug screening applications
From the themed collection: Organ-, body- and disease-on-a-chip systems
Paper

Bioprinted thrombosis-on-a-chip

A novel bioprinted model of thrombosis was developed to study thrombosis and thrombolysis in vitro.

Graphical abstract: Bioprinted thrombosis-on-a-chip
From the themed collection: Organ-, body- and disease-on-a-chip systems
10 items

About this collection

A collection of papers and reviews on organ-, body- and disease-on-a-chip research focussing on the interface between the technological advancements and high impact applications of organ-, body- and disease-on-a-chip technologies. This on-going collection is collated by Thought leader Michael Shuler and the Lab on a Chip Editorial Board.

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