Themed collection Journal of Materials Chemistry B Recent Review Articles
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Nanomaterials enabled and enhanced DNA-based biosensors
For biosensors based on DNA or aptamer probes and nanomaterials, aside from studying DNA adsorption and desorption, it is also important to examine the effect of target adsorption and other possible surface interaction mechanisms.
J. Mater. Chem. B, 2023,11, 6994-7003
https://doi.org/10.1039/D3TB01100C
Recent advances in double network hydrogels based on naturally-derived polymers: synthesis, properties, and biological applications
This review highlights recently developed double network hydrogels containing naturally-derived polymers, including discussion of synthetic methods, mechanical properties, and biological applications.
J. Mater. Chem. B, 2023,11, 11460-11482
https://doi.org/10.1039/D3TB00773A
Recent advancements in Mg-based micromotors for biomedical and environmental applications
Synthetic micro/nanomotors have attracted considerable attention due to their promising potential in the field of biomedicine.
J. Mater. Chem. B, 2023,11, 11483-11495
https://doi.org/10.1039/D3TB02339G
The green synthesis and applications of biological metal–organic frameworks for targeted drug delivery and tumor treatments
Application and development of synthesized bio-MOFs via a green approach (solvent-free and solvent-based green syntheses) for targeted drug delivery and tumor treatment.
J. Mater. Chem. B, 2023,11, 11426-11459
https://doi.org/10.1039/D3TB01959D
Zinc-based biomaterials for bone repair and regeneration: mechanism and applications
In this review, the specific mechanisms of bone formation promotion by Zn-based biomaterials are discussed, and recent developments in their applications in bone tissue engineering are summarized.
J. Mater. Chem. B, 2023,11, 11405-11425
https://doi.org/10.1039/D3TB01874A
Nano-scale drug delivery systems for luteolin: advancements and applications
Nano-scale drug delivery systems including micelles, nanocarrier-based systems, emulsified drug delivery systems, and vesicular drug delivery systems were designed for luteolin.
J. Mater. Chem. B, 2023,11, 11198-11216
https://doi.org/10.1039/D3TB01753B
A review of recent research and development on GLP-1 receptor agonists-sustained-release microspheres
This review provides key points in the development of glucagon-like peptide-1 receptor agonist-loaded microspheres from three aspects: preparation methods, strategies to maintain peptide bioactivity, and control the drug release from microspheres.
J. Mater. Chem. B, 2023,11, 11184-11197
https://doi.org/10.1039/D3TB02207B
Harnessing biomaterial architecture to drive anticancer innate immunity
Structure-driven immunomodulatory biomaterial design enhances innate immune activation against the tumor microenvironment to drive anticancer immunity.
J. Mater. Chem. B, 2023,11, 10982-11005
https://doi.org/10.1039/D3TB01677C
Conducting polymer-based scaffolds for neuronal tissue engineering
Neuronal tissue engineering has immense potential for treating neurological disorders and facilitating nerve regeneration.
J. Mater. Chem. B, 2023,11, 11006-11023
https://doi.org/10.1039/D3TB01838E
Biomass-derived 2D carbon materials: structure, fabrication, and application in electrochemical sensors
The latest methods and mechanisms of BC material synthesis and their applications in electrochemical sensors are systematically reviewed. The challenges and prospects of BC in building electrochemical sensors are also emphasized.
J. Mater. Chem. B, 2023,11, 10793-10821
https://doi.org/10.1039/D3TB01910A
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Recent advances and prospects in nanomaterials for bacterial sepsis management
This review highlights the significant potential of nanomedicines, including improved drug delivery, enhanced diagnostics, and immunomodulation for bacterial sepsis.
J. Mater. Chem. B, 2023,11, 10778-10792
https://doi.org/10.1039/D3TB02220J
Smart stimuli-responsive polysaccharide nanohydrogels for drug delivery: a review
Polysaccharides have found extensive utilization as biomaterials in drug delivery systems owing to their remarkable biocompatibility, simple functionalization, and inherent biological properties.
J. Mater. Chem. B, 2023,11, 10538-10565
https://doi.org/10.1039/D3TB01712E
Application of exosomes as nanocarriers in cancer therapy
Schematic illustration of exosomes, including: (i) exosome formation and distribution; (ii) characterization of exosomes; (iii) extraction and isolation techniques of exosomes; (iv) recent advances and applications of exosomes in cancer therapy.
J. Mater. Chem. B, 2023,11, 10595-10612
https://doi.org/10.1039/D3TB01991H
Metal–organic gels: recent advances in their classification, characterization, and application in the pharmaceutical field
As a new multifunctional soft substance, MOGs have been used as excellent carriers or smart materials in the pharmaceutical field.
J. Mater. Chem. B, 2023,11, 10566-10594
https://doi.org/10.1039/D3TB01612A
Advancement in total hip implant: a comprehensive review of mechanics and performance parameters across diverse novelties
A projected hip implant with the combination of a collared and FGM porous structure.
J. Mater. Chem. B, 2023,11, 10507-10537
https://doi.org/10.1039/D3TB01469J
Recent advances in smart wearable sensors as electronic skin
Flexible and multifunctional electronic devices and soft robots inspired by human organs, such as skin, have many applications.
J. Mater. Chem. B, 2023,11, 10332-10354
https://doi.org/10.1039/D3TB01373A
Recent advances in tailoring stimuli-responsive hybrid scaffolds for cardiac tissue engineering and allied applications
Deciphering the role of stimuli-responsive materials in modulating surrounding matrix properties, and cardiomyocyte maturation and behaviour resulting in generation of functionally active cardiac tissues.
J. Mater. Chem. B, 2023,11, 10297-10331
https://doi.org/10.1039/D3TB00450C
Organ bioprinting: progress, challenges and outlook
This review deliberates the current progress in organ bioprinting, including the heart, kidneys, liver, pancreas, and lungs. Challenges and future trends related to the biomanufacturing of living organs are discussed.
J. Mater. Chem. B, 2023,11, 10263-10287
https://doi.org/10.1039/D3TB01630G
Genetically engineered bacteria: a new frontier in targeted drug delivery
Genetically engineered bacteria have emerged as an exciting frontier in targeted drug delivery.
J. Mater. Chem. B, 2023,11, 10072-10087
https://doi.org/10.1039/D3TB01805A
Fluorescence imaging of peripheral nerve function and structure
Timeline of the key achievements in developing nerve-labeling fluorescence agents, including neuroanatomical tract tracers, small organic molecules, antibodies, and peptides.
J. Mater. Chem. B, 2023,11, 10052-10071
https://doi.org/10.1039/D3TB01927F
Cell or cell derivative-laden hydrogels for myocardial infarction therapy: from the perspective of cell types
Injectable hydrogels and cell-based myocardial infarction (MI) therapy mutually enhance each other. This review focuses on recent studies using hydrogel to deliver cell or cell-derived preparations for MI treatment.
J. Mater. Chem. B, 2023,11, 9867-9888
https://doi.org/10.1039/D3TB01411H
Single-atom nanozymes: classification, regulation strategy, and safety concerns
This review categorizes and describes the applications of SAzymes, explores methods for regulating their activity, and provides a comprehensive overview of the biosafety challenges associated with these enzymes.
J. Mater. Chem. B, 2023,11, 9840-9866
https://doi.org/10.1039/D3TB01644G
Activatable probes with potential for intraoperative tumor-specific fluorescence-imaging guided surgery
This review mainly describes the design principles and mechanisms of activatable probes for the fluorescence imaging of tumors.
J. Mater. Chem. B, 2023,11, 9777-9797
https://doi.org/10.1039/D3TB01590D
Cascade strategy for glucose oxidase-based synergistic cancer therapy using nanomaterials
Nanomaterial-based cancer therapy faces significant limitations due to the complex nature of the tumor microenvironment (TME).
J. Mater. Chem. B, 2023,11, 9798-9839
https://doi.org/10.1039/D3TB01325A
Harnessing the power of polyol-based polyesters for biomedical innovations: synthesis, properties, and biodegradation
Polyesters based on polyols have emerged as promising biomaterials for various biomedical applications, such as tissue engineering and drug delivery systems, due to their biocompatibility, biodegradability, and versatile physicochemical properties.
J. Mater. Chem. B, 2023,11, 9597-9629
https://doi.org/10.1039/D3TB01186K
Review on vat photopolymerization additive manufacturing of bioactive ceramic bone scaffolds
Bone defects frequently occur in clinical settings due to trauma, disease, tumors, and other causes.
J. Mater. Chem. B, 2023,11, 9572-9596
https://doi.org/10.1039/D3TB01236K
Antibacterial functionalized carbon dots and their application in bacterial infections and inflammation
Antimicrobial mechanisms of functionalized carbon dots: covalent and non-covalent interactions, reactive oxygen species, photothermal effect, and size effect (E. coli was used as a model).
J. Mater. Chem. B, 2023,11, 9386-9403
https://doi.org/10.1039/D3TB01543B
Current emerging novel therapies for Alzheimer's disease and the future prospects of magneto-mechanical force therapy
This article introduces the latest AD treatment techniques from three aspects: drug therapy, biological therapy and physical therapy. Nanoparticle-mediated therapeutics at nanomaterial–neural interfaces and biological systems are described in detail.
J. Mater. Chem. B, 2023,11, 9404-9418
https://doi.org/10.1039/D3TB01629C
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Comprehensive evaluation and advanced modification of polymethylmethacrylate cement in bone tumor treatment
Schematic illustration of the comprehensive evaluation and advanced modification of PMMA cement in bone tumor treatment.
J. Mater. Chem. B, 2023,11, 9369-9385
https://doi.org/10.1039/D3TB01494K
Synthesis approaches of amphiphilic copolymers for spherical micelle preparation: application in drug delivery
ROP, ATRP, RAFT and combined methods were employed for copolymer synthesis. The synthesized copolymers have proficiency of self-assembly into micellar structures.
J. Mater. Chem. B, 2023,11, 9325-9368
https://doi.org/10.1039/D3TB01371E
Virus-like particles nanoreactors: from catalysis towards bio-applications
Virus-like particles (VLPs) are self-assembled supramolecular structures in nature for compartmentalization. We summarize the current progress of protein cage nanoreactors spanning multilength scales, and highlight the emerging field of VLP based nanoreactors for biomedical applications.
J. Mater. Chem. B, 2023,11, 9084-9098
https://doi.org/10.1039/D3TB01112G
A review of zeolitic imidazolate frameworks (ZIFs) as electrochemical sensors for important small biomolecules in human body fluids
The emergence of ZIFs-based composite materials as promising candidates for electrochemical sensors of important small biomolecules in human body fluids.
J. Mater. Chem. B, 2023,11, 9099-9127
https://doi.org/10.1039/D3TB01221B
Recent strategies of carbon dot-based nanodrugs for enhanced emerging antitumor modalities
A comprehensive review of specific measures to improve the anti-tumor effects of carbon dot-based nanodrugs.
J. Mater. Chem. B, 2023,11, 9128-9154
https://doi.org/10.1039/D3TB00718A
Functional material-mediated wireless physical stimulation for neuro-modulation and regeneration
In this review, the mechanism by which various physical signals regulate neural cell behavior is summarized. And the progress of functional material-mediated indirect wireless physical stimulation for neuro-modulation and regeneration is reviewed.
J. Mater. Chem. B, 2023,11, 9056-9083
https://doi.org/10.1039/D3TB01354E
Bismuth-based two-dimensional nanomaterials for cancer diagnosis and treatment
We summarize the recent progress including controllable synthesis, defect engineering, surface modifications, applications, and prospects of Bi-based two-dimensional nanomaterials for cancer diagnosis and treatment.
J. Mater. Chem. B, 2023,11, 8866-8882
https://doi.org/10.1039/D3TB01544K
Intelligent sensing based on active micro/nanomotors
In this review, we delved into an elaborate exposition of different detection principles reliant on micro/nanomotors (MNMs), explore the challenges encountered by MNMs under distinct detection principles, and discuss potential future solutions.
J. Mater. Chem. B, 2023,11, 8897-8915
https://doi.org/10.1039/D3TB01163A
3D gradient printing based on digital light processing
3D gradient printing helps fabricate objects with gradually changing properties. Here we provide a conceptual understanding of gradient materials, covering current techniques and strategies, as well as their limitations and challenges.
J. Mater. Chem. B, 2023,11, 8883-8896
https://doi.org/10.1039/D3TB00763D
Red emissive carbon dots: a promising next-generation material with intracellular applicability
In this article, we present a thorough review on the use of RCDs in biomedical applications, including in vivo and in vitro bioimaging, photoacoustic imaging, monitoring temperature and polarity changes in living cells, tumour therapy, and drug delivery.
J. Mater. Chem. B, 2023,11, 8848-8865
https://doi.org/10.1039/D3TB01378B
Rational design and engineering of polypeptide/protein vesicles for advanced biological applications
The rational design and engineering strategies, employed in polypeptide/protein vesicles, from synthesis to assembly, for advanced biological and medical applications.
J. Mater. Chem. B, 2023,11, 8834-8847
https://doi.org/10.1039/D3TB01103H
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Anti-inflammatory role of gold nanoparticles in the prevention and treatment of Alzheimer's disease
In Alzheimer's disease, AuNPs may reduce neuroinflammation by induction of macrophage polarization, reduction of pro-inflammatory cytokine expression, restraint of leukocyte adhesion, and reduction of oxidative stress.
J. Mater. Chem. B, 2023,11, 8605-8621
https://doi.org/10.1039/D3TB01023F
Immunotherapy: cancer immunotherapy and its combination with nanomaterials and other therapies
Immunotherapy is a new type of tumor treatment. In this review, the main focus is on an overview of the research progress of immunotherapy in cancer treatment and the combined application of immunotherapy with other therapeutic approaches.
J. Mater. Chem. B, 2023,11, 8586-8604
https://doi.org/10.1039/D3TB01358H
Functional anti-bone tumor biomaterial scaffold: construction and application
This review summarizes the advances in biomaterial scaffolds with different functionalization strategies for bone tumors. It will provide a valuable reference for bone tumor clinical treatment.
J. Mater. Chem. B, 2023,11, 8565-8585
https://doi.org/10.1039/D3TB00925D
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A Trojan horse approach for efficient drug delivery in photodynamic therapy: focus on taxanes
This review discusses unique nanosystems combining taxanes with photosensitizers as multimodal chemo- and phototherapeutics for cancer treatment.
J. Mater. Chem. B, 2023,11, 8622-8638
https://doi.org/10.1039/D2TB02147A
Platinum based theranostics nanoplatforms for antitumor applications
Platinum (Pt) based nanoplatforms are biocompatible nanoagents with photothermal antitumor performance, while exhibiting excellent radiotherapy sensitization properties.
J. Mater. Chem. B, 2023,11, 8387-8403
https://doi.org/10.1039/D3TB01035J
Application of nanotechnology in bladder cancer diagnosis and therapeutic drug delivery
Application of nanomaterials in the diagnosis and treatment of BC.
J. Mater. Chem. B, 2023,11, 8368-8386
https://doi.org/10.1039/D3TB01323E
Supramolecular immunotherapy on diversiform immune cells
Supramolecular immunotherapy employs supramolecular materials to stimulate the immune system for inhibiting tumor cell growth and metastasis, reducing the cancer recurrence rate, and improving the quality of the patient's life.
J. Mater. Chem. B, 2023,11, 8347-8367
https://doi.org/10.1039/D3TB00924F
Beyond traditional light: NIR-II light-activated photosensitizers for cancer therapy
This review focuses on the recent progress of various NIR-II photosensitizers for photodynamic therapy, and briefly presents the ongoing challenges and prospects of NIR-II photosensitizers for clinical translation.
J. Mater. Chem. B, 2023,11, 8315-8326
https://doi.org/10.1039/D3TB00668A
Transdermal drug delivery via microneedles for musculoskeletal systems
Microneedles, with the advantages of oral administration and local injection, have become a novel strategy for administration and treatment of musculoskeletal diseases. We emphasized the progress and broad applications of MN-based transdermal drug delivery for MSK systems.
J. Mater. Chem. B, 2023,11, 8327-8346
https://doi.org/10.1039/D3TB01441J
Control of charge transport in electronically active systems towards integrated biomolecular circuits (IbC)
Crafting integrated biomolecular circuits (IbC) via self-assembly of electronically active molecules using a “bottom-up” paradigm provides a potential solution to the technological challenges of the miniaturization of silicon-based electronics.
J. Mater. Chem. B, 2023,11, 8302-8314
https://doi.org/10.1039/D3TB00701D
Recent advances in glucose-oxidase-based nanocomposites for diabetes diagnosis and treatment
Development of GOx-based nanomaterials for diabetes diagnosis and treatment.
J. Mater. Chem. B, 2023,11, 7582-7608
https://doi.org/10.1039/D3TB01097J
Nanomaterials: a promising multimodal theranostics platform for thyroid cancer
Thyroid cancer, the most common malignancy in the head and neck region, has shown an increasing incidence trend. With the continuous advancement of nanotechnology, nanomaterials hold great promise in providing diagnosis and treatment of thyroid cancer.
J. Mater. Chem. B, 2023,11, 7544-7566
https://doi.org/10.1039/D3TB01175E
Cardiac organoid: multiple construction approaches and potential applications
This review summarizes the current classification and construction methods of cardiac organoid, and describes its potential applications.
J. Mater. Chem. B, 2023,11, 7567-7581
https://doi.org/10.1039/D3TB00783A
Melanin: insights into structure, analysis, and biological activities for future development
A comprehensive review of melanin's structure, identification methods, and biological activities, highlighting its potential for further development and diverse applications in various fields.
J. Mater. Chem. B, 2023,11, 7528-7543
https://doi.org/10.1039/D3TB01132A
Synthetic strategies, properties and sensing application of multicolor carbon dots: recent advances and future challenges
Preparation strategies, optical properties, and sensing application of multicolor carbon dots.
J. Mater. Chem. B, 2023,11, 8117-8135
https://doi.org/10.1039/D3TB01329D
Antioxidative 0-dimensional nanodrugs overcome obstacles in AKI antioxidant therapy
Schematic illustration of 0D nanodrugs for AKI treatment. (a) Pathological features of renal tubular injury and glomerular filtration barrier in AKI. (b) Three categories of 0D nanomaterials applied to nanodrugs surrounding AKI antioxidant therapy.
J. Mater. Chem. B, 2023,11, 8081-8095
https://doi.org/10.1039/D3TB00970J
Design, strategies, and therapeutics in nanoparticle-based siRNA delivery systems for breast cancer
This paper reviews the design considerations of nanoparticle-based siRNA delivery systems to improve their efficacy and safety. The strategies for overcoming in vivo delivery barriers are discussed.
J. Mater. Chem. B, 2023,11, 8096-8116
https://doi.org/10.1039/D3TB00278K
Design and fabrication of intracellular therapeutic cargo delivery systems based on nanomaterials: current status and future perspectives
Intracellular cargo delivery is an important strategy for deciphering cell function, directing cell fate, and reprogramming cell behavior.
J. Mater. Chem. B, 2023,11, 7873-7912
https://doi.org/10.1039/D3TB01008B
Polyphosphate as an antithrombotic target and hemostatic agent
Applications of polyphosphate (PolyP) and PolyP inhibitors in biomedicine.
J. Mater. Chem. B, 2023,11, 7855-7872
https://doi.org/10.1039/D3TB01152F
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Tuning foreign body response with tailor-engineered nanoscale surface modifications: fundamentals to clinical applications
The synergistic effect of nanotopography and chemistry in modulating different stages of the foreign body response, impacting cell–protein–biomaterial interactions.
J. Mater. Chem. B, 2023,11, 7834-7854
https://doi.org/10.1039/D3TB01040F
MicroRNA therapeutics and nucleic acid nano-delivery systems in bacterial infection: a review
In a game of humans versus pathogenic microbes, will MicroRNAs be a key weapon for humans to defeat bacterial infections?
J. Mater. Chem. B, 2023,11, 7804-7833
https://doi.org/10.1039/D3TB00694H
Advances in hydrogels for the treatment of periodontitis
This review presents the lastest advances in the treatment of periodontitis with hydrogels. The pathogenic mechanisms of periodontitis are presented, as well as the progress of hydrogel controlling inflammation and tissue reconstruction.
J. Mater. Chem. B, 2023,11, 7321-7333
https://doi.org/10.1039/D3TB00835E
Potential of graphene-based nanomaterials for cardiac tissue engineering
Graphene and its derivatives have many desirable characteristics that make them suitable for use in cardiac tissue engineering.
J. Mater. Chem. B, 2023,11, 7280-7299
https://doi.org/10.1039/D3TB00654A
Oxygen-releasing biomaterials for regenerative medicine
This review provides a comprehensive overview of oxygen-releasing biomaterials for regenerative medicine.
J. Mater. Chem. B, 2023,11, 7300-7320
https://doi.org/10.1039/D3TB00670K
Advances and perspectives of nanozymes in respiratory diseases
This is a systematic review of advances and perspectives of nanozymes in respiratory diseases, which will inspire communities of researchers and build a bridge between nanozymes and respiratory medicine.
J. Mater. Chem. B, 2023,11, 7041-7054
https://doi.org/10.1039/D3TB00930K
Application of cell membrane-functionalized biomimetic nanoparticles in the treatment of glioma
Different kinds of cell membrane-functionalized biomimetic nanoparticles utilized for glioma therapy.
J. Mater. Chem. B, 2023,11, 7055-7068
https://doi.org/10.1039/D3TB00605K
Antibacterial black phosphorus nanosheets for biomedical applications
This review highlights the potential of black phosphorus nanosheets (BPNs) in treating bacterial infections, addressing their unique properties as well as the challenges and prospects of their antibacterial applications in biomedicine.
J. Mater. Chem. B, 2023,11, 7069-7093
https://doi.org/10.1039/D3TB00723E
Nanocellulose-based hydrogels for drug delivery
This article presents a comprehensive review of the preparation methods, carrier forms, and key parameters of nanocellulose-based hydrogels as drug delivery systems. And it proposes potential research directions.
J. Mater. Chem. B, 2023,11, 7004-7023
https://doi.org/10.1039/D3TB00478C
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Therapy and diagnosis of Alzheimer's disease: from discrete metal complexes to metal–organic frameworks
Critical analysis of discrete metal compounds and metal–organic frameworks (MOFs) as a platform for the treatment and/or diagnosis of Alzheimer's disease.
J. Mater. Chem. B, 2023,11, 7024-7040
https://doi.org/10.1039/D3TB00427A
Metal–organic frameworks (MOFs) as apt luminescent probes for the detection of biochemical analytes
This article reviews the recent developments in the use of MOF materials as probes and biosensing platforms for diverse chemicals (H2O2, metal ions, H2S, GSH, and nucleic acids) in biological cells.
J. Mater. Chem. B, 2023,11, 6802-6822
https://doi.org/10.1039/D3TB00505D
Development of nanozyme based sensors as diagnostic tools in clinic applications: a review
Nanozyme-based sensors in the field of healthcare.
J. Mater. Chem. B, 2023,11, 6762-6781
https://doi.org/10.1039/D3TB00451A
About this collection
This collection contains recent Review-type articles published by Journal of Materials Chemistry B, the home for high impact applications, properties and synthesis of exciting new materials for biology and medicine. New articles will be added to this collection as soon as possible after publication.