Issue 20, 2023

Development of a by-product-free strategy for the synthesis of oxazoline from N-acetylglucosamine

Abstract

This study focused on the CDMBI-mediated synthesis of GlcNAc oxazoline. Through our research, we uncovered and characterized a previously unreported by-product. We proposed a mechanism for its formation and developed a new strategy to prevent its occurrence. These findings represent an important step towards gaining a deeper understanding of this reaction and may provide a new avenue for optimizing the oxazoline synthesis.

Graphical abstract: Development of a by-product-free strategy for the synthesis of oxazoline from N-acetylglucosamine

Supplementary files

Article information

Article type
Communication
Submitted
21 mar 2023
Accepted
30 apr 2023
First published
08 maj 2023

New J. Chem., 2023,47, 9532-9535

Development of a by-product-free strategy for the synthesis of oxazoline from N-acetylglucosamine

S. Zhou, M. Bo, F. Tang, W. Liu, X. Li, B. Chen, S. Shang, W. Huang, Y. Li and Z. Tan, New J. Chem., 2023, 47, 9532 DOI: 10.1039/D3NJ01323E

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