Themed collection Bioinspired Surfaces Engineering for Biomaterials
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Introduction to bioinspired surfaces engineering for biomaterials
G. Julius Vancso, Jian Ji, Kazuhiko Ishihara, M. Cristina L. Martins and Shaoyi Jiang introduce the Journal of Materials Chemistry B themed collection on bioinspired surfaces engineering for biomaterials.
J. Mater. Chem. B, 2022,10, 2277-2279
https://doi.org/10.1039/D2TB90044K
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Synthetic strategies to enhance the long-term stability of polymer brush coatings
We discuss potential causes for degrafting of polymer brushes and provide an overview of the synthetic strategies that can be utilized to prevent degrafting.
J. Mater. Chem. B, 2022,10, 2430-2443
https://doi.org/10.1039/D1TB02605D
Antimicrobial peptide-based materials: opportunities and challenges
The design of antimicrobial peptide-based materials for biomedical applications such as fighting infections in various organs, cancer therapy, gene delivery and detection of bacteria.
J. Mater. Chem. B, 2022,10, 2384-2429
https://doi.org/10.1039/D1TB02617H
Engineering surface patterns on nanoparticles: new insights into nano-bio interactions
The surface patterns of gold nanoparticles, dendrimers and DNA nanostructures are explored as a model to provide new insights into nano-bio interactions.
J. Mater. Chem. B, 2022,10, 2357-2383
https://doi.org/10.1039/D1TB02549J
Recent advances of zwitterionic-based topological polymers for biomedical applications
Zwitterionic-based topological polymers and their derivatives possess diverse topological structures and have been widely used in biomedical fields.
J. Mater. Chem. B, 2022,10, 2338-2356
https://doi.org/10.1039/D1TB02323C
Recent progress and perspectives in applications of 2-methacryloyloxyethyl phosphorylcholine polymers in biodevices at small scales
This review offers a bird's eye view of the development and application of 2-methacryloyloxyethyl phosphorylcholine (MPC) polymers in small biodevices such as microfluidic devices, biosensors/bioprobes, artificial implants, and drug delivery systems.
J. Mater. Chem. B, 2022,10, 2323-2337
https://doi.org/10.1039/D1TB02675E
Self-targeting of zwitterion-based platforms for nano-antimicrobials and nanocarriers
Different anionic and cationic groups occurring in zwitterions, and the pH responsive groups required for self-targeting. The different steps in self-targeting are outlined in the outer circle, numbered in the order of occurrence during self-targeting.
J. Mater. Chem. B, 2022,10, 2316-2322
https://doi.org/10.1039/D1TB02647J
Recent progress in tannic acid-driven antibacterial/antifouling surface coating strategies
Tannic acid-based bioinspired coating strategies for tethering functional materials or molecules on different medical substrates for resisting bacterial pathogens and fouling agents.
J. Mater. Chem. B, 2022,10, 2296-2315
https://doi.org/10.1039/D1TB02073K
Fundamentals and exploration of aggregation-induced emission molecules for amyloid protein aggregation
This review provides a first systematic summary of aggregation-induced emission (AIE) molecules for amyloid protein aggregates associated with neurodegenerative diseases.
J. Mater. Chem. B, 2022,10, 2280-2295
https://doi.org/10.1039/D1TB01942B
Concentrated polymer brush-modified cellulose nanofibers promote chondrogenic differentiation of human mesenchymal stem cells by controlling self-assembly
A new three-dimensional cell culture system for articular cartilage regeneration was developed, in which concentrated polymer brush-modified cellulose nanofibers were utilized as building blocks for the self-assembly of human mesenchymal stem cells.
J. Mater. Chem. B, 2022,10, 2444-2453
https://doi.org/10.1039/D1TB02307A
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Poly-phosphocholination of liposomes leads to highly-extended retention time in mice joints
PMPCylated liposomes injected into mice joints show a massive increase in retention half-life compared with PEGylated liposomes (or hyaluronan, HA), making them promising candidates as boundary lubricants at articular cartilage, or as drug carriers.
J. Mater. Chem. B, 2022,10, 2820-2827
https://doi.org/10.1039/D1TB02346B
Dual-responsive zwitterion-modified nanopores: a mesoscopic simulation study
DPD simulations were adopted to study the pH- and salt-responsiveness of nanopores modified by zwitterionic PCBMA brushes, in which the switching of nanopores can be modulated by the grafting density and chain length of brushes.
J. Mater. Chem. B, 2022,10, 2740-2749
https://doi.org/10.1039/D1TB02416G
Surfaces with antifouling-antimicrobial dual function via immobilization of lysozyme on zwitterionic polymer thin films
A novel coating with antifouling and antimicrobial dual functions was fabricated to prevent transmission and spread of infectious diseases.
J. Mater. Chem. B, 2022,10, 2728-2739
https://doi.org/10.1039/D1TB02597J
Photoinduced immobilization of 2-methacryloyloxyethyl phosphorylcholine polymers with different molecular architectures on a poly(ether ether ketone) surface
Poly(ether ether ketone) (PEEK) has seen increasing use in biomedical fields as a replacement for metal implants.
J. Mater. Chem. B, 2022,10, 2699-2707
https://doi.org/10.1039/D1TB02415A
Preclinical testing of an anal bulking agent coated with a zwitterionic polymer in a fecal incontinence rat model
The use of zwitterion-coated particulate silicone as a bulking agent for the treatment of fecal incontinence was investigated in a rat model.
J. Mater. Chem. B, 2022,10, 2708-2718
https://doi.org/10.1039/D1TB02341A
Janus membranes with asymmetric cellular adhesion behaviors for regenerating eardrum perforation
A Janus membrane can not only heal the tympanic membrane perforation with its hydrophilic surface, but also possesses the anti-adhesion properties due to its hydrophobic surface.
J. Mater. Chem. B, 2022,10, 2719-2727
https://doi.org/10.1039/D1TB02418C
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Short-wave and near infrared π-conjugated polymers hosted in a biocompatible microemulsion: a pioneering approach for photoacoustic contrast agents
Biocompatible, non- ionic oil-in-water (O/W) microemulsion was developed to encapsulate and deliver novel lipophilic polymers possessing photoacoustic properties.
J. Mater. Chem. B, 2022,10, 2680-2690
https://doi.org/10.1039/D1TB02257A
Antibacterial thyme oil-loaded zwitterionic emulsion hydrogels
An emulsion hydrogel composed of thyme-oil and PSBMA was prepared by enzyme-mediated polymerization, holding promise as an antibacterial wound dressing with sustained drug release.
J. Mater. Chem. B, 2022,10, 2691-2698
https://doi.org/10.1039/D1TB02853G
Molecular simulations of zwitterlation-induced conformation and dynamics variation of glucagon-like peptide-1 and insulin
Zwitterionic materials have shown their ability to improve the circulation time and stability of proteins.
J. Mater. Chem. B, 2022,10, 2490-2496
https://doi.org/10.1039/D1TB02561A
A biomimetic anti-biofouling coating in nanofluidic channels
A biomimetic coating using a tailored phosphorylcholine-containing monomer enables to suppress non-specific protein adsorption in nanofluidic channels, paving a way to explore a new anti-biofouling strategy using monomer-based materials for nanodevices.
J. Mater. Chem. B, 2022,10, 2481-2489
https://doi.org/10.1039/D1TB02627E
Photoresponsive behaviour of zwitterionic polymer particles with photodimerizable groups on their surfaces
Photoresponsive zwitterionic polymer particles that undergo photo-assembling by ultraviolet light irradiation are designed as smart nanomaterials with the bioinert surface.
J. Mater. Chem. B, 2022,10, 2637-2648
https://doi.org/10.1039/D1TB02342J
Verteporfin-loaded supramolecular micelles for enhanced cisplatin-based chemotherapy via autophagy inhibition
Cisplatin and autophagy inhibitor verteporfin co-loaded zwitterionic supramolecular micelles were fabricated. The therapeutic efficacy of cisplatin-based chemotherapy could be enhanced by the inhibition of autophagy.
J. Mater. Chem. B, 2022,10, 2670-2679
https://doi.org/10.1039/D1TB02583J
One-step electrochemical deposition of antifouling polymers with pyrogallol for biosensing applications
One-step electrochemical deposition of polysulfobetaine with pyrogallol creates an antifouling sensing platform for the detection of biomarkers.
J. Mater. Chem. B, 2022,10, 2504-2511
https://doi.org/10.1039/D1TB02536H
Zwitterionic peptide-functionalized highly dispersed carbon nanotubes for efficient wastewater treatment
A novel modification strategy for enhancing the dispersity of MWCNTs was developed using a chimeric protein MPKE, which consisted of a zwitterionic peptide unit and a mussel adhesive protein unit. The MPKE-MWCNTs could in situ load AgNPs for 4-NP reduction.
J. Mater. Chem. B, 2022,10, 2661-2669
https://doi.org/10.1039/D1TB02348A
Bioinspired photo-responsive membrane enhanced with “light-cleaning” feature for controlled molecule release
Inspired by the stomatal feature of plant leaves, a photo-responsive membrane was developed to enhance the removal of irreversible membrane fouling and to control molecule release.
J. Mater. Chem. B, 2022,10, 2617-2627
https://doi.org/10.1039/D1TB02329B
Bio-inspired antibacterial coatings on urinary stents for encrustation prevention
Mussel-inspired antibacterial and anti-encrustation coatings on urinary stents could in situ inhibit bacterial growth and biofilm formation, and finally reduce deposition of struvite and hydroxyapatite crystals both in vitro and in vivo.
J. Mater. Chem. B, 2022,10, 2584-2596
https://doi.org/10.1039/D1TB02318G
Phospholipid polymer hydrogels with rapid dissociation for reversible cell immobilization
Polymer hydrogels were prepared via gently mixing a PMB–MAPBA and PVA. The hydrogels can be easily dissociated after the addition of D-sorbitol, and immobilize cells without any reduction in bioactivity.
J. Mater. Chem. B, 2022,10, 2628-2636
https://doi.org/10.1039/D1TB02316K
Zwitterionic choline phosphate conjugated folate-poly (ethylene glycol): a general decoration of erythrocyte membrane-coated nanoparticles for enhanced tumor-targeting drug delivery
A general decoration of erythrocyte membrane-coated nanoparticles for enhanced tumor-targeting drug delivery based on the “CP–PC” interaction of MCP-PEG-FA and erythrocyte membranes.
J. Mater. Chem. B, 2022,10, 2497-2503
https://doi.org/10.1039/D1TB02493K
Sulfobetaine polymers for effective permeability into multicellular tumor spheroids (MCTSs)
Hydroxy group containing methacrylamide polymers exhibited excellent permeability into the hepatocyte multicellular tumor spheroids.
J. Mater. Chem. B, 2022,10, 2649-2660
https://doi.org/10.1039/D1TB02337C
A bioinspired Janus polyurethane membrane for potential periodontal tissue regeneration
Here, we developed a bioinspired degradable polyurethane membrane with Janus surface morphology and function by integrating the bioactive dopamine (DA) and the antibacterial Gemini quaternary ammonium salt (QAS).
J. Mater. Chem. B, 2022,10, 2602-2616
https://doi.org/10.1039/D1TB02068D
A QCM study of strong carbohydrate–carbohydrate interactions of glycopolymers carrying mannosides on substrates
The carbohydrate–carbohydrate interaction was demonstrated by glyco-cluster with glycopolymers and could be measured quantitatively.
J. Mater. Chem. B, 2022,10, 2597-2601
https://doi.org/10.1039/D1TB02344F
Carboxy-terminal dendrimers with phenylalanine for a pH-sensitive delivery system into immune cells including T cells
Dendrimers with phenylalanine (Phe) and cyclohexanedicarboxylic acid (CHex) showed higher uptake into various cells including T cells via endocytosis. The cell association was enhanced under weak acidic conditions observed in tumor microenvironment.
J. Mater. Chem. B, 2022,10, 2463-2470
https://doi.org/10.1039/D1TB01980E
Induction of mesenchymal stem cell differentiation by co-culturing with mature cells in double-layered 2-methacryloyloxyethyl phosphorylcholine polymer hydrogel matrices
Mesenchymal stem cells can be encapsulated 3-dimensionally in a spontaneously forming polymer hydrogel. Differentiation of the cells is effectively induced by close-contact co-culturing with mature cells encapsulated in different polymer hydrogels.
J. Mater. Chem. B, 2022,10, 2561-2569
https://doi.org/10.1039/D1TB01817E
Fibrillated bacterial cellulose liquid carbene bioadhesives for mimicking and bonding oral cavity surfaces
Tunable mucoadhesive platform that allows crosslinking of shape conforming viscous liquids to elastic adhesive hydrogels in under a minute proposed for application to diseased sites in the oral cavity.
J. Mater. Chem. B, 2022,10, 2570-2583
https://doi.org/10.1039/D1TB02044G
Preparation of a thermo-responsive drug carrier consisting of a biocompatible triblock copolymer and fullerene
Water-soluble C70/triblock copolymer complexes can be used as carriers that release encapsulated drugs when heated and as photosensitizers for photodynamic therapy.
J. Mater. Chem. B, 2022,10, 2551-2560
https://doi.org/10.1039/D1TB02183D
A natural polysaccharide-based antibacterial functionalization strategy for liquid and air filtration membranes
A natural polysaccharide-based strategy was developed for the facile and universal antimicrobial functionalization of filtration materials.
J. Mater. Chem. B, 2022,10, 2471-2480
https://doi.org/10.1039/D1TB02273C
Accelerated tissue regeneration in decellularized vascular grafts with a patterned pore structure
Tissue regeneration in decellularized vascular grafts was accelerated with a patterned pore structure.
J. Mater. Chem. B, 2022,10, 2544-2550
https://doi.org/10.1039/D1TB02271G
Molecularly-imprinted hydrogel beads via self-sacrificing micro-reactors as safe and selective bilirubin adsorbents
Brand new PAA–SS–rGO@BIL hydrogel beads as safe and self-anticoagulant BIL absorbents in the field of hemoperfusion.
J. Mater. Chem. B, 2022,10, 2534-2543
https://doi.org/10.1039/D1TB01895G
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Development of polymer-based multifunctional composite particles of protease and peroxidase activities
A polymer-based nanocomposite of dual enzyme function was developed to achieve joint protease and peroxidase activities.
J. Mater. Chem. B, 2022,10, 2523-2533
https://doi.org/10.1039/D1TB01861B
Bioinspired NO release coating enhances endothelial cells and inhibits smooth muscle cells
Introducing nitric oxide (NO) to traditional drug-eluting stents alleviates incomplete endothelialization and further inhibit the stenosis caused by the proliferation of smooth muscle cells.
J. Mater. Chem. B, 2022,10, 2454-2462
https://doi.org/10.1039/D1TB01828K
Effect of liposome surface modification with water-soluble phospholipid polymer chain-conjugated lipids on interaction with human plasma proteins
Alternative liposome surface coatings for PEGylation to evade the immune system, particularly the complement system, have garnered significant interest.
J. Mater. Chem. B, 2022,10, 2512-2522
https://doi.org/10.1039/D1TB01485D
About this collection
Understanding the sophisticated functionalities offered by objects and processes found in nature will guide the design of materials with desirable properties to meet challenging applications. Zwitterionic and other materials, inspired by biological structures and functions at different levels (e.g. cell membrane, protein, tissues etc.) have shown great potential in diagnostic, drug delivery and tissue regeneration applications.
This themed issue of Journal of Materials Chemistry B is focused on recent rapid development in bioinspired biomaterials. It aims at covering the recent progress on zwitterionic materials specifically and other bioinspired biomaterials broadly, including properties, applications, and synthesis of bioinspired and zwitterionic materials related to biology and medicine, bioinspired surfaces/interfaces, fabrication and functionality of bioinspired nanoparticles, high-throughput methods and applications in nanomedicine, nanodiagnostics, medical devices, sensors, scaffolds for tissue regeneration etc. We hope you enjoy these articles published in this Journal of Materials Chemistry B collection Guest Edited by Professor Jian Ji (Zhejiang University), Professor Kazuhiko Ishihara (The University of Tokyo), Professor Shaoyi Jiang (Cornell University), Professor M. Cristina L. Martins (Universidade do Porto) and Professor G. Julius Vancso (University of Twente).