Issue 10, 2022

Bis(cholyl)-based chloride channels with oxalamide and hydrazide selectivity filters

Abstract

We report the development of supramolecular bis(cholyl) ion channels using oxalamide and hydrazide as selectivity filters. The hydrazide system showed superior chloride transport activity to oxalamide via the formation of a barrel stave channel. The better chloride recognition within the hydrazide channel over the oxalalmide channel was confirmed from the theoretical calculations.

Graphical abstract: Bis(cholyl)-based chloride channels with oxalamide and hydrazide selectivity filters

Supplementary files

Article information

Article type
Communication
Submitted
16 10 2021
Accepted
07 2 2022
First published
08 2 2022

Org. Biomol. Chem., 2022,20, 2054-2058

Bis(cholyl)-based chloride channels with oxalamide and hydrazide selectivity filters

R. Sharma, A. Vijay, A. Mukherjee and P. Talukdar, Org. Biomol. Chem., 2022, 20, 2054 DOI: 10.1039/D1OB02028E

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements