Themed collection Chemical Communications HOT Articles 2024
Electrocatalytic water-to-oxygenates conversion: redox-mediated versus direct oxygen transfer
Elucidating the oxygen transfer route can facilitate the development of electro-catalytic oxygenation reactions. Herein, we introduce oxygen transfer routes including the redox-mediated pathway and the direct oxygen transfer (DOT) method.
Chem. Commun., 2024,60, 7523-7534
https://doi.org/10.1039/D4CC01960A
MXene’s value addition role as photo/ electrocatalysts in water splitting for sustainable hydrogen production
Chem. Commun., 2024, Accepted Manuscript
https://doi.org/10.1039/D4CC01811G
Electrifying oxidation of ethylene and propylene
This highlight discusses the advantages of various oxidation methods for improved performance of the electrochemical oxidation of ethylene and propylene, and provides an overview of current challenges and problems requiring further efforts.
Chem. Commun., 2024,60, 6703-6716
https://doi.org/10.1039/D4CC02025A
Mechanism-based and data-driven modeling in cell-free synthetic biology
This highlight discusses state-of-the-art mechanism-based modeling and machine-learning approaches in cell-free synthetic biology and their potential for designing and optimizing novel genetic circuits.
Chem. Commun., 2024,60, 6466-6475
https://doi.org/10.1039/D4CC01289E
Recent advances in C(sp3)–N bond formation via metallaphoto-redox catalysis
In this review, the state-of-the-art advances in radical-involved C(sp3)–N bond formation via metallaphotoredox catalysis have been highlighted, which are organized according to different catalytic modes, reaction types, and substrate classes.
Chem. Commun., 2024,60, 6340-6361
https://doi.org/10.1039/D4CC01969E
Recent developments in photocatalytic production of hydrogen peroxide
This highlight article summarizes the recent developments and challenges in photocatalytic production of hydrogen peroxide and looks forward to the development direction of this field.
Chem. Commun., 2024,60, 5354-5368
https://doi.org/10.1039/D4CC01577K
Recent advances in electrosynthesis of H2O2via two-electron oxygen reduction reaction
This review provides an electrosynthesis strategy of H2O2via the 2e− ORR, covering aspects of reaction mechanisms, performance assessment, catalyst engineering, and setups for scaling up H2O2 production.
Chem. Commun., 2024,60, 5232-5244
https://doi.org/10.1039/D4CC01476F
Enantioselective merged gold/organocatalysis
This highlight demonstrates the state of the art in the field of the enantioselective merged gold/organocatalysis by leveraging the unique reactivity of each catalyst.
Chem. Commun., 2024,60, 3607-3623
https://doi.org/10.1039/D4CC00114A
Visual monitoring of biocatalytic processes using small molecular fluorescent probes: strategies-mechanisms-applications
Real-time monitoring of biocatalytic-based processes is significantly improved and simplified when they can be visualized.
Chem. Commun., 2024,60, 2716-2731
https://doi.org/10.1039/D3CC05626K
Catalysts and electrolyzers for the electrochemical CO2 reduction reaction: from laboratory to industrial applications
To cope with the environmental pollution and energy shortage, reducing carbon dioxide molecules and producing fuels and chemicals via electrocatalytic methods, is one of the effective pathways to achieve carbon neutrality.
Chem. Commun., 2024,60, 1207-1221
https://doi.org/10.1039/D3CC05453E
Mechanistic insights into facilitating reductive elimination from Ni(II) species
The possible modes have been summarized to disclose the reductive elimination from Ni(II) species.
Chem. Commun., 2024, Advance Article
https://doi.org/10.1039/D4CC02667E
Ru(0)-catalysed synthesis of borylated polyene building blocks by cross-dimerisation toward cross-coupling
A series of borylated polyenes is synthesised by cross-dimerisation as a synthetic building block for cross-coupling reactions.
Chem. Commun., 2024, Advance Article
https://doi.org/10.1039/D4CC02566K
Recent advances in circularly polarized luminescence of planar chiral organic compounds
This review overviews recent research on circularly polarized luminescence from planar chiral organic compounds, focusing on their synthetic strategies, properties and applications.
Chem. Commun., 2024,60, 6728-6740
https://doi.org/10.1039/D4CC01698J
Cationic ligands – from monodentate to pincer systems
Incorporation of cationic ligands within pincer frameworks allowed to develop them from obscure peculiarities into a diverse class of ancillary ligands.
Chem. Commun., 2024, Advance Article
https://doi.org/10.1039/D4CC01489H
Metal–organic framework (MOF)-based materials for pyroptosis-mediated cancer therapy
This manuscript summarized the recent progress of MOF-based pyroptosis inducers in immunotherapy.
Chem. Commun., 2024,60, 6476-6487
https://doi.org/10.1039/D4CC02084G
Hydrogen bond types which do not fit accepted definitions
There are various interactions that either partially fit or do not fit the currently accepted definitions of the hydrogen bond.
Chem. Commun., 2024,60, 6239-6255
https://doi.org/10.1039/D4CC01769B
All-atom molecular dynamics simulations of polymer and polyelectrolyte brushes
New discoveries on polymer and polyelectrolyte brush systems and the corresponding brush-supported ions and water, arising from employing all-atom molecular dynamics simulations, have been thoroughly reviewed.
Chem. Commun., 2024,60, 6093-6129
https://doi.org/10.1039/D4CC01557F
Molecule engineering strategy of toll-like receptor 7/8 agonists designed for potentiating immune stimuli activation
We highlighted the recent research progress concerning the molecule engineering strategy of toll-like receptor 7/8 agonists for enhancing immunotherapy, including our research work and some related emerging works.
Chem. Commun., 2024,60, 5474-5485
https://doi.org/10.1039/D4CC00792A
Cascade ring expansion reactions for the synthesis of medium-sized rings and macrocycles
Recent advances in the development of cascade ring expansion reactions for the synthesis of medium-sized rings and macrocycles are described.
Chem. Commun., 2024,60, 4999-5009
https://doi.org/10.1039/D4CC01303D
Cooperative small molecule activation by apolar and weakly polar bonds through the lens of a suitable computational protocol
Through the magnifying glass of a suitable computational protocol, both support and guidance of experimental advances in small molecules activation mediated by apolar and weakly polar bonds are made possible.
Chem. Commun., 2024,60, 1222-1238
https://doi.org/10.1039/D3CC05614G
Artificial transmembrane potassium transporters: designs, functions, mechanisms and applications
In this review, we provide the very first comprehensive exposition of artificial potassium transporters developed mostly over the past ten years.
Chem. Commun., 2024,60, 482-500
https://doi.org/10.1039/D3CC04488B
Emerging sensing platforms based on Cucurbit[n]uril functionalized gold nanoparticles and electrodes
Cucurbit[n]uril functionalized gold nanoparticles and electrodes facilitate the development of sensing platforms based on recognition tunneling, surface-enhanced Raman spectroscopy, single molecule force spectroscopy, and electrochemical methods.
Chem. Commun., 2024,60, 150-167
https://doi.org/10.1039/D3CC04851A
Sample transformation in online separations: how chemical conversion advances analytical technology
Sample transformation can be used to provide insights into the properties of complex samples.
Chem. Commun., 2024,60, 36-50
https://doi.org/10.1039/D3CC03599A
A three-component hydrogen bonded framework
A porous three-component hydrogen bonded framework is prepared from a tetra-amidinium cation and two different dicarboxylate anions.
Chem. Commun., 2024,60, 7582-7585
https://doi.org/10.1039/D4CC02265C
Synthesis and photoluminescence properties of polymer chains based on pre-designed heterometallic Al4Ln4 molecular rings
For the first time, we herein report a series of chain compounds based on pre-designed heterometallic aluminum–lanthanide (Al–Ln) molecular rings through ligand linkages.
Chem. Commun., 2024,60, 7574-7577
https://doi.org/10.1039/D4CC01611D
2D metal–organic frameworks bearing butterfly-shaped metal-bis(dithiolene) linkers from dithiol-functionalized benzenedicarboxylic acid
2D metal-bis(dithiolene) frameworks can be achieved easily either by a stepwise protocol using a butterfly-shaped intermediate or by direct assembly using transition metal ions and 1,4-dicarboxylbenzene-2,3-dithiol.
Chem. Commun., 2024,60, 7578-7581
https://doi.org/10.1039/D4CC02282C
Metal- and additive-free β-C(sp2)–H decarboxylative alkylsulfonylation of enamides from phenyliodine(III) dicarboxylates and sulfur dioxide
A green process for the direct C(sp2)–H decarboxylative alkylsulfonylation of enamides under metal- and additive-free conditions is reported.
Chem. Commun., 2024, Advance Article
https://doi.org/10.1039/D4CC02865A
Structure of the caffeine–pyrogallol complex: revisiting a pioneering structural analysis of a model pharmaceutical cocrystal
The herein revisited 1967 attempt of structural analysis of the solid-state complex of caffeine and pyrogallol was a pioneering investigation of what today would be seen as a prototypical pharmaceutical cocrystal model system.
Chem. Commun., 2024,60, 7431-7434
https://doi.org/10.1039/D4CC02289K
Tetraphenylpentalenide organolanthanide complexes
Chem. Commun., 2024, Accepted Manuscript
https://doi.org/10.1039/D4CC02570A
Electrode switch—an efficient induced approach for self-activation of an electrode toward water splitting
This work breaks through the traditional concept and provides a novel electrode switch (ES) method to improve the stability of the alkaline electrolyzer.
Chem. Commun., 2024,60, 7315-7318
https://doi.org/10.1039/D4CC01830C
Porous organic crystals crosslinked by free-radical reactions
Olefin-rich hydrogen-bonded crosslinked organic frameworks (HCOFs) were crosslinked via free radical reactions and subsequently converted to a hydroxylated HCOF.
Chem. Commun., 2024,60, 7311-7314
https://doi.org/10.1039/D4CC02454K
Catalytic effect of microflow space for supramolecular block co-polymerization of water-soluble porphyrins
Microflow power plant opens up a new kinetic pathway to make new non-covalent bonds.
Chem. Commun., 2024,60, 7303-7306
https://doi.org/10.1039/D4CC02003K
Metal–organic framework/Nb4C3Tx MXene composites for ultrasensitive detection of dopamine
Composites with excellent performances for dopamine electrochemical sensing were prepared by in situ synthesis of metal–organic frameworks in presence of exfoliated Nb4C3Tx MXenes.
Chem. Commun., 2024,60, 7307-7310
https://doi.org/10.1039/D4CC00694A
CO2 cleavage by tantalum/M (M = iridium, osmium) heterobimetallic complexes
A novel Ta/Os complex [Ta(CH2tBu)3(μ-H)3OsCp*], and its iridium analogue [Ta(CH2tBu)3(μ-H)2IrCp*], efficiently cleave CO2 under mild conditions, forming tantalum oxo species and CpIr(CO)H2 or CpOs(CO)H3.
Chem. Commun., 2024, Advance Article
https://doi.org/10.1039/D4CC02207F
Optically active poly(diphenylacetylene)s showing solvent-dependent helix inversion accompanied by modulation of helix inversion barriers
Poly(diphenylacetylene)s bearing chiral 2-octyloxycarbonyl groups show a solvent-dependent helix inversion accompanied by a solvent-dependent changes in the helix inversion barrier.
Chem. Commun., 2024, Advance Article
https://doi.org/10.1039/D4CC02656J
Amplification of negative gas adsorption in a multivariate framework
Tailoring of framework micromechanics using the multivariate MOF approach allowed stabilization of the metastable overloaded state and double the ΔnNGA value compared to original values in DUT-49.
Chem. Commun., 2024, Advance Article
https://doi.org/10.1039/D4CC02540G
Length dependent reversible off–on activation of photo-switchable relay anion transporters
A homologous series of photo-switchable relay anion transporters is reported. Length and shape of the relay influences the rate of transport, enabling visible light regulation of activity and tunability of the irradiation wavelength.
Chem. Commun., 2024,60, 7160-7163
https://doi.org/10.1039/D4CC02603A
9-Step synthesis of (−)-larikaempferic acid methyl ester enabled by skeletal rearrangement
A 9-step synthesis of (−)-larikaempferic acid methyl ester is achieved via a skeletal rearrangement strategy and controlled transannular aldol reaction.
Chem. Commun., 2024,60, 7164-7167
https://doi.org/10.1039/D4CC01462F
Singlet oxygen is an emissive ligand
Experimental evidence of the existence of a ZnTPP–O2 complex following photosensitization at the solid–gas interface is presented, confirming prior hypotheses.
Chem. Commun., 2024, Advance Article
https://doi.org/10.1039/D4CC02011A
Pathway to a molecular calcium methyl
The hydrocarbon-soluble β-diketiminato calcium zincate and molecular calcium methyl dimer are accessible from reacting ZnMe2 and [(BDI)CaH]2. The calcium methyl corrects a notable omission from the homologous series of alkylcalcium derivatives.
Chem. Commun., 2024, Advance Article
https://doi.org/10.1039/D4CC02930E
Aromaticity transfer in an annulated 1,4,2-diazaborole: facile access to Cs symmetric 1,4,2,5-diazadiborinines
A tricyclic annulated 1,4,2-diazaborole reacts with hydrido-, fluoro-, and chloro-boranes to form 6-membered diazadiborinine derivatives. Reduction of these latter products leads to the first examples of Cs symmetric 1,4,2,5-diazadiborinines.
Chem. Commun., 2024, Advance Article
https://doi.org/10.1039/D4CC02414A
Alkali Metal Reduction of Crown Ether Encapsulated Alkali Metal Cations
Chem. Commun., 2024, Accepted Manuscript
https://doi.org/10.1039/D4CC02725F
Tuneable thiol exchange linkers for traceless drug release applications in prodrugs and ADCs
We describe a versatile and tuneable thiol responsive linker system using thiovinylketones, that relies on the conjugate addition–elimination mechanism of Michael acceptors for the traceless release of therapeutics.
Chem. Commun., 2024,60, 7025-7028
https://doi.org/10.1039/D4CC01558D
Rapid production of 38 mM H2O2 in an alcoholic suspension of a WO3 photocatalyst under visible light
At 60 °C, a high concentration of H2O2 was rapidly produced in a 90 vol% IPA suspension of a cocatalyst-free WO3 photocatalyst.
Chem. Commun., 2024,60, 7017-7020
https://doi.org/10.1039/D4CC01402B
Light-induced β-hydroxy sulfone synthesis in DNA-encoded libraries
Visible-light photooxidation of sulfinate salts with common alkenes to yield β-hydroxy sulfones on DNA for DNA-encoded library synthesis.
Chem. Commun., 2024,60, 6885-6888
https://doi.org/10.1039/D4CC02193B
Direct photocatalytic C–H functionalization mediated by a molybdenum dioxo complex
Direct photocatalytic C–H activation is achieved with the transition metal oxo complex MoO2Cl2(bpy-tBu). The reoxidation conditions and mechanism, catalytic benchmarking, and stability limiting factors are presented.
Chem. Commun., 2024,60, 6901-6904
https://doi.org/10.1039/D4CC01789G
P(V)-bis(amidophenolate) ligand cooperation: stoichiometric CO-bond cleavage in aldehydes and ketones
The cleavage of the CO bond of aldehydes and ketones is achieved by the cooperation of a highly electrophilic P(V)-centre and its supporting tetradentate bis(amidophenolate) ligand.
Chem. Commun., 2024,60, 6745-6748
https://doi.org/10.1039/D4CC02202E
Synthesis of dihydrotropone derivatives using an anionic 8π-electrocyclic reaction
A new method to synthesise functionalised cycloheptatrienes was established using the anionic 8π-electrocyclic reaction of β-ketoester-derived dienyne substrates.
Chem. Commun., 2024,60, 6619-6622
https://doi.org/10.1039/D4CC02273D
Observing atomically precise nanocluster aggregates in solution by mass photometry
We report the first mass photometric characterization of nanoaggregates of atomically precise nanoclusters (NCs) in solution.
Chem. Commun., 2024,60, 6655-6658
https://doi.org/10.1039/D4CC00363B
Insights into dynamic structural evolution and its sodium storage mechanisms of P2/P3 composite cathode materials for sodium-ion batteries
Through a heterostructure modulation strategy, P2/P3-Na0.44Mn0.7Co0.3O2 was successfully synthesized as a high-rate and long-cycle cathode material for sodium-ion batteries.
Chem. Commun., 2024,60, 6496-6499
https://doi.org/10.1039/D4CC02166E
Formation of iminium ions during the processing of metal halide perovskites
In acetone, powders of the hexagonal perovskite (Me2NH2)PbI3 are rapidly transformed to the iminium-based perovskite (Me2CNMe2)PbI3.
Chem. Commun., 2024,60, 6488-6491
https://doi.org/10.1039/D4CC01735H
A π-extended molecular belt with selective binding capability for fullerene C70
A molecular belt [8]NCP incorporating naphthalene moieties was precisely engineered through bottom–up synthesis. It exhibits remarkable selective binding ability for C70 compared to C60, forming a 1 : 1 complex.
Chem. Commun., 2024,60, 6387-6390
https://doi.org/10.1039/D4CC01966K
Construction of a tetrabenzotetrathia[8]circulene by a “fold-in” oxidative fusion reaction: synthesis and optical properties
A saddle-shaped tetrabenzotetrathia[8]circulene was synthesized by a “fold-in” type oxidative fusion reaction of an ortho-phenylene-bridged cyclic tetrathiophene, which exhibits fluorescence at room temperature and phosphorescence at low temperature.
Chem. Commun., 2024,60, 6264-6267
https://doi.org/10.1039/D4CC01598C
Evaluating the native oxide of titanium as an electrocatalyst for oxalic acid reduction
Titanium electrodes bearing the naturally-forming native oxide coating are competent for the electroreduction of oxalic acid to glyoxylate and glycolate.
Chem. Commun., 2024,60, 6003-6006
https://doi.org/10.1039/D4CC01176G
Enantioselective de novo synthesis of 14-hydroxy-6-oxomorphinans
The enantioselective de novo synthesis of pharmacologically important 14-hydroxy-6-oxomorphinans is described. 4,5-Desoxynaltrexone and 4,5-desoxynaloxone were prepared using this route and their biological activities against the opioid receptors were measured.
Chem. Commun., 2024,60, 6007-6010
https://doi.org/10.1039/D4CC01788A
Characterization of the first Peacock–Weakley polyoxometalate containing a transplutonium element: curium bis-pentatungstate [Cm(W5O18)2]9−
Leveraging microgram-level techniques, we here present the first transplutonium bis-pentatungstate complex: NaCs8Cm(W5O18)2·14H2O (CmW5).
Chem. Commun., 2024,60, 5999-6002
https://doi.org/10.1039/D4CC01381F
Deville rebooted – practical N2O5 synthesis
UV irradiation is used for the efficient production of dinitrogen pentoxide.
Chem. Commun., 2024,60, 5920-5923
https://doi.org/10.1039/D4CC01403K
3D printing of reactive macroporous polymers via thiol–ene chemistry and polymerization-induced phase separation
Using thiol–ene chemistry, polymerization-induced phase separation, and DLP 3D printing, we present a method for manufacturing reactive macroporous 3D structures.
Chem. Commun., 2024,60, 5872-5875
https://doi.org/10.1039/D4CC00466C
Redox-reversible siderophore-based catalyst anchoring within cross-linked artificial metalloenzyme aggregates enables enantioselectivity switching
The cross-linking of redox-reversible artificial metalloenzyme aggregates produces recyclable protein microparticles that enable catalyst replacement and hence catalyst-controlled enantioselectivity switching.
Chem. Commun., 2024,60, 5490-5493
https://doi.org/10.1039/D4CC01158A
Construction of supramolecular antibacterial material based on water-soluble pillar[5]arene and zwitterionic guest molecule
Chem. Commun., 2024, Accepted Manuscript
https://doi.org/10.1039/D4CC01737D
Unlocking Lewis acidity via the redox non-innocence of a phenothiazine-substituted borane
A bench-top stable borane with an appended redox-active phenothiazine motif can be oxidized by a single-electron oxidant to “unlock” a potent radical cationic Lewis acid catalyst for dimerization and hydrosilylation reactions.
Chem. Commun., 2024,60, 5391-5394
https://doi.org/10.1039/D4CC01059K
Construction of thioglycoside bonds via an asymmetric organocatalyzed sulfa-Michael/aldol reaction: access to 4′-thionucleosides
The construction of S–C–N glycosidic bonds via the organocatalytic sulfa-Michael/aldol reaction of (E)-β-nucleobase acrylketone and 1,4-dithiane-2,5-diol was achieved, and diverse 4′-thionucleosides were obtained with excellent results.
Chem. Commun., 2024,60, 5018-5021
https://doi.org/10.1039/D4CC00984C
Z-selective radical difunctionalization of aromatic alkynes: synthesis of multi-substituted triarylethenes
Described herein is a Cu-catalyzed diarylation of aromatic alkynes via radical docking-migration pathways, leading to a broad range of valuable triarylethenes.
Chem. Commun., 2024,60, 4894-4897
https://doi.org/10.1039/D4CC01315H
Evaluation of aconitine cardiotoxicity with a heart-on-a-particle prepared by a microfluidic device
A heart-on-a-particle model based on a multicompartmental microgel is proposed to simulate the heart microenvironment and study the cardiotoxicity of drugs.
Chem. Commun., 2024,60, 4898-4901
https://doi.org/10.1039/D4CC00396A
A small-molecule Fenton reagent for self-augmented chemodynamic therapy by intelligently regulating intracellular acidosis
A small-molecule Fenton reagent was developed to self-augment chemodynamic therapy by intelligently regulating intracellular acidosis.
Chem. Commun., 2024,60, 4773-4776
https://doi.org/10.1039/D4CC00760C
Dissipative sequential catalysis via six-component machinery
Triphenyl phosphane (TPP) and an epoxide as a fuel system transiently transformed a non-catalytic six-component turnstile into a four-component catalytic rotor releasing N-methyl pyrrolidine and a copper(I) complex.
Chem. Commun., 2024,60, 4659-4662
https://doi.org/10.1039/D4CC00786G
Photoredox-catalyzed carbonylative acylation of styrenes with Hantzsch esters
A three-component carbonylation that provides a new method for the synthesis of ketones from Hantzsch esters has been developed.
Chem. Commun., 2024,60, 4656-4658
https://doi.org/10.1039/D4CC01293C
Highly substituted benzo[b]furan synthesis through substituent migration
An unusual benzofuran synthesis from 2,6-disubstituted phenols and alkynyl sulfoxides is disclosed. Various highly-substituted benzofurans were synthesized via a charge-accelerated [3,3]-sigmatropic rearrangement and subsequent substituent migration.
Chem. Commun., 2024,60, 4545-4548
https://doi.org/10.1039/D4CC01192A
Covalent organic framework isomers with divergent photocatalytic properties
Minute structural variations in Py-BT-COF isomers can generate significant differences in redox and photophysical properties, resulting in divergent photocatalytic performances in H2 reduction and rhodamine B degradation.
Chem. Commun., 2024,60, 4423-4426
https://doi.org/10.1039/D4CC00130C
A new armchair carbon nanobelt synthesized by tuning the regioselectivity of the Scholl reaction of quinquephenyl
A new armchair carbon nanobelt is successfully synthesized by tuning the regioselectivity of the Scholl reaction of the quinquephenyl units in the arylated [12]cycloparaphenylene substrate.
Chem. Commun., 2024,60, 4314-4317
https://doi.org/10.1039/D4CC00979G
About this collection
This ongoing web-collection features the articles published in ChemComm in 2024 that have been marked as HOT by our Editors and trusted Reviewers. Many Congratulations to all those featured!