Themed collection Soft Matter Open Access Spotlight 2026
Liquid–liquid phase separation as a structuring tool for designing anisotropic food systems
Anisotropic structures formed by flow-induced deformation and arrest in aqueous two-phase system (ATPS). Increasing deformation orients the dispersed phase. Once the structure is arrested, this anisotropy is locked in and transferred to the final product.
Soft Matter, 2026,22, 2780-2792
https://doi.org/10.1039/D5SM01134E
The hidden wheel-within
Yes, animals do have wheels! Their generalized wheel – the “wheel-within” – is used across all clades of life, yet stayed long concealed in plain sight. Only its reinvention in soft robotics opened our eyes to its ubiquitous role in Nature.
Soft Matter, 2026,22, 2597-2607
https://doi.org/10.1039/D5SM01041A
Replicable 2.5D PDMS microfluidics with precision nanoscale features expand the dimensions of pore-scale flow studies
Customizable 2.5D microfluidic chips, tailored for rock-on-a-chip studies of pore-scale transport phenomena, are developed using direct laser writing (DLW) and soft lithography.
Soft Matter, 2026,22, 2466-2473
https://doi.org/10.1039/D5SM01004G
Probing the limits of effective temperature consistency in actively driven systems
We experimentally probe whether a consistent effective temperature can characterize the nonequilibrium steady state of a passive tracer driven by a fully athermal active environment.
Soft Matter, 2026,22, 297-305
https://doi.org/10.1039/D5SM00840A
Modeling tumor transport and growth with poroelastic biopolymer networks
Poroelastic fluid outflow dominates stress relaxation in biopolymer networks. A balance between compression-driven advection and diffusion regulates the availability of growth factors and subsequent tumor proliferation in computational simulations.
Soft Matter, 2026,22, 2907-2924
https://doi.org/10.1039/D6SM00060F
Symmetry breaking of interacting charge-regulated planar macroions at low salt concentration
The charge of macroions such as colloids and membranes can often be regulated by reversible ion adsorption or dissociation reactions.
Soft Matter, 2026,22, 2880-2892
https://doi.org/10.1039/D6SM00194G
Shape, confinement and inertia effects on the dynamics of a driven spheroid in a viscous fluid
Force-driven spheroids in confinement reveal rich and intricate dynamics determined by particle aspect ratio, strength of confinement, and fluid inertia.
Soft Matter, 2026,22, 2856-2869
https://doi.org/10.1039/D6SM00038J
Droplet breakup against an isolated obstacle
Quasi-2D droplets pushed by fluid have predictable breakup behavior against cylindrical obstacles.
Soft Matter, 2026,22, 2809-2822
https://doi.org/10.1039/D5SM01266J
Association and dissociation of Na+ between bulk, cluster and micelle sites in aqueous sodium decanoate solutions elucidated by 23Na NMR relaxation experiments and quadrupolar relaxation modelling
This study uses 23Na NMR and quadrupolar relaxation modelling to quantify Na+ partitioning between bulk water, aggregates, and micelles in decanoate solutions, revealing weak binding below the CMC and stronger association at higher concentration.
Soft Matter, 2026,22, 2800-2808
https://doi.org/10.1039/D5SM01198A
Tunable thin elasto-drops
Ultra-thin elastic capsules behave as droplets with tunable surface tension. Hydro-elastic waves reveal membrane tension, establishing “elasto-drops” as a model system for tension-dominated soft interfaces.
Soft Matter, 2026,22, 2793-2799
https://doi.org/10.1039/D5SM01192B
Phase diagrams of conformationally asymmetric pentablock copolymer melts: a theory and simulation study
MD simulations and SCFT calculations to predict phase diagrams for pentablock copolymers with conformationally asymmetric blocks modeled as chains with unequal stiffness or bead diameters.
Soft Matter, 2026,22, 2733-2745
https://doi.org/10.1039/D5SM01223F
Establishing direct relationships between soft material perception and rheology
In soft materials, a clear relationship between material properties and human sensory perception has long been desired for design of consumer products, but the link has remained evasive.
Soft Matter, 2026,22, 2666-2677
https://doi.org/10.1039/D5SM01286D
Nonequilibrium phases of a biomolecular condensate facilitated by enzyme activity
Energy-dependent helicase activity and RNA secondary structure work together to preserve an initial nonequilibrium state of condensate homogeneity and dynamics.
Soft Matter, 2026,22, 2656-2665
https://doi.org/10.1039/D5SM01106J
Decoupling the structural origins of strength and toughness in industrially relevant heterogeneous elastomers
For randomly crosslinked elastomers, coarse-grained MD shows that strength is set by network topology (cycle rank), whereas toughness depends on effective chain ratio and strand-length uniformity, providing a rational design strategy for elastomers.
Soft Matter, 2026,22, 2704-2712
https://doi.org/10.1039/D6SM00007J
Ionic-content-driven restructuring of spirobisindane ionene networks: implications for mechanics, self-healing, and gas transport
Reconfigurable microporous ionene networks that pair permanent PIM porosity with intrinsic ionic self-healing. Hierarchical ionic interactions govern structure, dynamics, and gas transport, offering general design rules for adaptive soft materials.
Soft Matter, 2026,22, 2608-2622
https://doi.org/10.1039/D6SM00105J
Retina microrheology via oscillatory atomic force microscopy
Oscillatory AFM measures the viscoelastic properties of samples, yielding advantages over traditional AFM when measuring biological tissues or materials.
Soft Matter, 2026,22, 2629-2637
https://doi.org/10.1039/D5SM01060H
Electric-field-induced switching of circularly polarized luminescence in a multicomponent emissive liquid-crystal system
Doping achiral organoplatinum complexes into a chiral nematic liquid crystal yields emissive materials exhibiting strong circularly polarized luminescence. The helical structure enables continuous, reversible CPL switching under a DC electric field.
Soft Matter, 2026,22, 2762-2768
https://doi.org/10.1039/D5SM01195G
Ultra-giant lipid vesicles functioning as a centimeter-sized smart chemical reactor
We report a simple and robust method for generating centimeter-sized lipid vesicles (ultra-giant lipid vesicles, UGLVs) that serve as stable chemical reactors undergoing rhythmic chemical reactions accompanied by chemical waves.
Soft Matter, 2026,22, 2482-2486
https://doi.org/10.1039/D5SM01226K
Nudging cell migration from within through microrod-induced morphological deformation
Motile Dictyostelium cells spontaneously internalize glass microrods. The resulting cell–rod composites align their velocity vectors with the rod axis and show enhanced migration persistence.
Soft Matter, 2026,22, 2578-2586
https://doi.org/10.1039/D5SM01149C
Mechanisms of electrolyte (coagulant) dipping for thin nitrile gloves
Two mechanisms for film deposition during the electrolyte dipping process are examined.
Soft Matter, 2026,22, 2526-2537
https://doi.org/10.1039/D5SM01262G
Using particle shape to control defects in colloidal crystals on spherical interfaces
For particles confined to a spherical interface, shape anisotropy changes the dominate lattice. The incompatibility between lattice symmetry and interface topology leads to a variety of defects with varying morphology and distribution.
Soft Matter, 2026,22, 2558-2567
https://doi.org/10.1039/D5SM01271F
Water droplet attraction and coalescence on liquid-crystal-infused textured and porous surfaces
Water droplets coalesce on liquid-crystal-infused surfaces via the same three-stage pathway as on slippery lubricant-infused porous surfaces (SLIPS), with ridge-mediated damping tuning the coalescence dynamics.
Soft Matter, 2026,22, 2545-2557
https://doi.org/10.1039/D5SM01184A
Pre-yielding mechanical response near the jamming transition
The mechanical and rheological properties of jammed packings of frictionless particles under shear strain remain not fully understood, even when the strain amplitude is very small and well below the yielding threshold.
Soft Matter, 2026,22, 2487-2498
https://doi.org/10.1039/D5SM01183C
The effect of charge density on the viscoelasticity and underwater adhesion of entangled complex coacervates from semi-rigid polysaccharides
Time–salt–charge density superposition reveals charge-density-dependent salt sensitivity in the complex coacervation of high-molecular-weight, semiflexible polyelectrolytes.
Soft Matter, 2026,22, 2499-2513
https://doi.org/10.1039/D5SM01220A
Quantification of cholesterol incorporation in giant unilamellar vesicles produced by a modified cDICE method
MβCD-mediated cholesterol incorporation into emulsion-based GUVs quantified in situ using environment-sensitive fluorescent dyes.
Soft Matter, 2026,22, 2408-2421
https://doi.org/10.1039/D5SM01124H
Response to dynamic shape changes in suspensions of hard rectangles
While the autonomous assembly of hard nanoparticles with different shapes has been studied extensively both in experiments and simulations, little is known about systems where particle shape can be dynamically altered.
Soft Matter, 2026,22, 2447-2455
https://doi.org/10.1039/D6SM00037A
Softening of shear-thickening in suspensions by the addition of large particles
Addition of very large particles softens the shear-thickening response. The magnitude of this softening increases systematically with particle size.
Soft Matter, 2026,22, 2379-2388
https://doi.org/10.1039/D5SM01144B
Liquid crystalline derivatives exhibiting smectic phases with ferro- and antiferro-electric properties
This work presents new smectogens possessing ferroelectric and antiferroelectric properties and the effect of the partial racemization of chiral molecular chains.
Soft Matter, 2026,22, 2389-2398
https://doi.org/10.1039/D6SM00028B
The effect of molecular shape and chemical structure on the photo-physical properties of liquid crystals
The molecular shape and chemical structure of liquid crystals greatly influence their flourescence properties.
Soft Matter, 2026,22, 2350-2363
https://doi.org/10.1039/D5SM01147G
Nonlinear elasticity and transition to macroscopic irreversibility in composite hydrogels
Filler-hydrogel composites exhibit viscoelastc properties with signatures of successive transitions from linear to non-linear elasticity to macroscopic irreversibility with increasing strain amplitude.
Soft Matter, 2026,22, 2290-2300
https://doi.org/10.1039/D5SM00990A
A new method to measure pore radius distribution of powders
A new method combines SEM imaging, deep learning, and a robust stereological algorithm to resolve sub-micron pore distributions in powders, outperforming X-ray tomography resolution.
Soft Matter, 2026,22, 2237-2248
https://doi.org/10.1039/D5SM01199J
Impacting spheres: from liquid drops to elastic beads
A liquid drop impacting a non-wetting rigid substrate spreads, retracts and rebounds, while an elastic sphere deforms slightly and bounces off. This work bridges these two limits and offers a framework for liquid-to-elastic transitions.
Soft Matter, 2026,22, 2226-2236
https://doi.org/10.1039/D5SM01078K
The effect of humidity, temperature, and drying duration on microparticle detachment force: insights into capillary-induced deformation at the particle–substrate interface
Drying capillary bridges that squeeze microparticles, enlarge contact, and strengthen adhesion.
Soft Matter, 2026,22, 2249-2258
https://doi.org/10.1039/D5SM01109D
Osmotic forces modify lipid membrane fluctuations
Osmotic forces alter thermal lipid membrane undulations, with long-wavelength fluctuations at moderate tensions no longer satisfying the well-known equipartition result.
Soft Matter, 2026,22, 2270-2278
https://doi.org/10.1039/D5SM01094B
A solvent-topology perspective on hydrophobic aggregation
Solvent topology exhibits a sharp, kernel-dependent connectivity crossover even when amphiphile aggregation evolves smoothly.
Soft Matter, 2026, Advance Article
https://doi.org/10.1039/D5SM01246E
4D printing of fully programmable sheets of digital metamaterials
This work resolves a long-standing challenge in 4D printing by enabling simultaneous material agnostic control of both lateral geometry and spontaneous curvature, unlocking a new design space for programmable shape-morphing materials.
Soft Matter, 2026, Advance Article
https://doi.org/10.1039/D5SM00780A
Rheological properties and shear-induced structures of ferroelectric nematic liquid crystals
Ferroelectric nematics DIO, RM734, and FNLC919 under shear exhibit three regimes as shear rate increases: flow alignment at low rates, polydomains at intermediate rates and log-rolling with polarization along the vorticity axis at high rates.
Soft Matter, 2026, Advance Article
https://doi.org/10.1039/D5SM01207D
Mechanical instabilities in drying protein droplets under substrate-free conditions
Understanding how proteins of different origins behave during drying is essential for controlling the mechanical stability and final structure of protein-based materials.
Soft Matter, 2026,22, 2184-2194
https://doi.org/10.1039/D5SM01113B
Virtual magnetic hills to unlock the inner phases of hexagonal colloidal ice
Colloidal spin ice uses tunable colloids to investigate geometric frustration phenomena. Combining mobile and fixed colloids, we report a charge-ordered topological phase in hexagonal geometry.
Soft Matter, 2026,22, 2122-2129
https://doi.org/10.1039/D5SM01277E
Controlled route to active turbulence: filling an activity spot with topological defects
Increasing the radius of an activity spot allows a controlled route to active turbulence in an active paranematic fluid by gradually filling in topological defects. An active paranematics is a suspension of rods that exhibits nematic order only under extensile activity.
Soft Matter, 2026,22, 2139-2152
https://doi.org/10.1039/D5SM01076D
Propulsion of laser printed polymer micro-rods by a low frequency electric field in nematic liquid crystals
The trajectory of a 3D-printed polymer microrod swimming in a nematic liquid crystal, as captured under a confocal microscope. The trajectory is helical-like and the rod is propelled by a low, 90 mHz frequency AC electric field of 0.56 V µm−1.
Soft Matter, 2026,22, 2107-2121
https://doi.org/10.1039/D5SM01104C
Machine learning approaches to quantify nanoscale variations in the mechanical properties of soft nanoparticles
We provide a framework for using machine learning classifiers to accurately and efficiently quantify the mechanical properties of soft materials on the nanoscale.
Soft Matter, 2026, Advance Article
https://doi.org/10.1039/D5SM00943J
Interactions of thermochromic liquid crystals with surface-modified PET substrates for thermal sensing applications
Shear-induced alignment and thermally-driven alignment contribute to the thermochromic behavior of the printed cholesteric liquid crystal; Hydrophobic substrate treatment intensifies its thermochromic response by reducing ink spreading.
Soft Matter, 2026,22, 2038-2051
https://doi.org/10.1039/D5SM01182E
Critical fluctuations of elastic moduli in jammed solids
Scaling behaviours of unstressed shear moduli.
Soft Matter, 2026,22, 2017-2025
https://doi.org/10.1039/D5SM01202C
Impact of protein corona morphology on nanoparticle diffusion in biological fluids: insights from a mesoscale approach
Using mesoscale Brownian dynamics simulations, we investigate the effect of protein corona morphology on nanoparticle transport and assess the accuracy of equivalent hydrodynamic sphere models in soft matter transport.
Soft Matter, 2026,22, 2066-2078
https://doi.org/10.1039/D5SM01152C
Circling crystals in chiral active matter with self-alignment
We study a crystal composed of active units and discover a circling crystal phase arising from the interplay of self-alignment and chirality.
Soft Matter, 2026,22, 2052-2065
https://doi.org/10.1039/D5SM01135C
The effect of thioester linkages on the stability of the ferroelectric nematic phase
The synthesis and characterisation of new thioester-containing ferroelectric nematic liquid crystals is reported. Their behaviour is analysed in terms of shape and electronic effects, and compared to that of their ester-linked counterparts.
Soft Matter, 2026,22, 1994-2003
https://doi.org/10.1039/D5SM01206F
How human-derived brain organoids are built differently from brain organoids derived from genetically-close relatives: a multi-scale hypothesis
Our new multiscale model proposes a critical nuclear strain that triggers ZEB2 activation, delayed in human-derived organoids.
Soft Matter, 2026,22, 1979-1993
https://doi.org/10.1039/D5SM01116G
Dynamic droplet behavior for analyte localization on phase change liquid infused surfaces
A phase change liquid infused surface that enables reversible solid and liquid lubricant state for microplastic localization.
Soft Matter, 2026,22, 1948-1961
https://doi.org/10.1039/D5SM00979K
Geometry-dependent transmission of externally imposed shear stress in confined microtubule–kinesin active fluids
Active fluids confined in thin cuboidal chambers transition from chaotic, turbulence-like flow to shear-dominated flow when imposed stresses exceed intrinsic active stresses, revealing how stress competition governs their response to external shear.
Soft Matter, 2026,22, 1933-1947
https://doi.org/10.1039/D5SM00871A
Molecular concentration field design using closed-form steady-state solutions
Control over spatial concentration fields represents a fundamental challenge in designing synthetic biological systems and programmable soft materials.
Soft Matter, 2026,22, 1839-1846
https://doi.org/10.1039/D5SM01121C
Complex molecular dynamics of symmetric model discotic liquid crystals: comparison of hexakis(hepta-alkanoyloxy)triphenylene (HOT6) with hexakis(hexa-alkyloxy)triphenylene (HAT6)
This study investigates the complex molecular dynamics of discotic liquid crystals by comparing two structurally similar compounds: hexakis(hepta-alkanoyloxy)triphenylene and hexakis(hexa-alkyloxy)triphenylene.
Soft Matter, 2026,22, 1863-1879
https://doi.org/10.1039/D5SM01247C
A skyrmionic topology perspective on Lehmann clusters
In cholesterics with pitch p, colliding dislocations with Burgers vectors b = p and b = −p form stable twin-like pairs, known as Lehmann clusters, which are immune against annihilation for topological reasons.
Soft Matter, 2026,22, 1825-1838
https://doi.org/10.1039/D5SM01244A
Exact integrated equations to describe diffusion kinetics
When modelling diffusion kinetics, the exact solutions for Fick's second law can be obtained by integration of Crank's equations. The provide more accurate diffusion constants compared to commonly used approximations.
Soft Matter, 2026,22, 1816-1824
https://doi.org/10.1039/D5SM01209K
Lipstick structure revealed by multimodal strain- and time-dependent rheology
Exploring the rheological properties of lipsticks through a multiscale experimental approach: from microstructure to cracking behavior.
Soft Matter, 2026,22, 1739-1754
https://doi.org/10.1039/D5SM01032B
A novel approach to measure needle insertion responses and the overlooked impact of insertion on injection outcomes
Needle-based injection techniques are widely used in drug delivery, diagnostics, and soft material characterization, yet the mechanical influence of the insertion process on the ensuing injection behavior remains poorly understood.
Soft Matter, 2026,22, 1755-1766
https://doi.org/10.1039/D5SM01023C
The shape of ribbons: from polymers to surfaces
Establishing a theoretical bridge between polymers and surfaces through the study of ribbons of variable width.
Soft Matter, 2026,22, 1790-1796
https://doi.org/10.1039/D5SM01001B
Viscoelastic properties of tumor spheroids revealed by a microfluidic compression device and a modified power law model
A microfluidic compression device for studies of living tissue mechanics. A FEM simulation shows piston deflection under the applied pressure, along with a microscopic image of a collagen embedded tumor spheroid with/without compression.
Soft Matter, 2026,22, 1618-1629
https://doi.org/10.1039/D5SM00949A
One-pot polymer–clay composite reversible adhesive
A single-formulation water-based and industrially scalable reversible adhesive was prepared from polyelectrolyte emulsions containing clays.
Soft Matter, 2026,22, 1591-1600
https://doi.org/10.1039/D5SM01039J
Tiny plastic, big trouble: how polystyrene nanoparticles impact DNA-damage repair deficient cervical cancer cells
Colloidal stability of micro- and nano-plastics influences interactions with human cells. These effects can be measured as a function of DNA damage repair via mitochondrial function, esterase activity, and oxidative stress.
Soft Matter, 2026,22, 1643-1654
https://doi.org/10.1039/D5SM01095K
Molecular picture of curing and incomplete cross-linking of epoxy at a solid interface
Near the solid interface, amines segregate and the molecules orient along the substrate, resulting in slower dynamics. After the reaction, isolated fragments, dangling chains, and unreacted monomers remain.
Soft Matter, 2026,22, 1583-1590
https://doi.org/10.1039/D5SM01089F
Drug & virus transport across biological barriers: interactions, diffusion, partitioning, permeability, and selectivity
Colloidal transport across biological barriers is modeled to capture roles of kT-scale interactions, hindered diffusion, and equilibrium partitioning, which can enable design of optimal drug particle coatings and comparisons to virus transport.
Soft Matter, 2026,22, 1630-1642
https://doi.org/10.1039/D5SM01176K
Mean-field model for the bubble size distribution in coarsening wet foams
A growth law for wet foams, which is validated against bubble-scale simulations, predicts a scaling-state size distribution with large numbers of small bubbles, similarly to recent experiments.
Soft Matter, 2026,22, 1601-1617
https://doi.org/10.1039/D5SM01007A
Epoxy coating to prolong actuation time in degas-driven PDMS micropumps
Self-powered micropumps to enhance the portability of Lab-on-a-Chip technology.
Soft Matter, 2026,22, 1679-1686
https://doi.org/10.1039/D5SM00964B
Spatially resolved fast dynamics reveal the aggregation mechanism in two-dimensions
Two morphologies and two mechanisms: 1. strong bonding that breaks occasionally, and 2. rattling within a cage of neighbors.
Soft Matter, 2026,22, 1562-1568
https://doi.org/10.1039/D5SM00672D
The influence of cellular energy status, microtubules, and crowding on mitochondrial motion
Mitochondrial motion in mammalian cells is affected by perturbation of cell energy, the microtubule network and cytoplasmic crowding in different ways, but prolongation of the time that mitochondria stall before longer movements is a main effect.
Soft Matter, 2026,22, 1510-1525
https://doi.org/10.1039/D5SM01174D
Order–disorder transition in soft and deformable particle assembly with dynamic size-dispersity in two dimensions
Particle line tension drives the order–disorder transition in assemblies of soft, deformable particles in two dimensions, while increasing dynamic size dispersity shifts the transition to higher line tension.
Soft Matter, 2026,22, 1551-1561
https://doi.org/10.1039/D5SM01097G
Colloidal rod dynamics under large amplitude oscillatory extensional flow
We investigate experimentally and theoretically the time-dependent orientation of rod-like colloids undergoing oscillatory extensional flows over a wide range of Péclet and Deborah numbers.
Soft Matter, 2026,22, 1389-1401
https://doi.org/10.1039/D5SM01122A
Tensile properties of single- and multi-type mixed fibre bundles of spider silk
Spider silk exhibits an outstanding range of mechanical properties – this versatility is further enhanced by the combination of two or more silk types in mixed fibre bundles.
Soft Matter, 2026,22, 1455-1472
https://doi.org/10.1039/D5SM01141H
Transient grating spectroscopy nondestructively characterizes the mechanics of rubbery polymers and soft gels
Combined measurements from transient grating spectroscopy and indentation are used to measure the Poisson’s ratio of diverse gels and elastomers with high degrees of precision and accuracy. All gels tested are observed to be nearly incompressible.
Soft Matter, 2026,22, 1367-1375
https://doi.org/10.1039/D5SM00835B
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Browse our 2026 Open Access articles!
All featured articles are published Gold Open Access and are free to read in Soft Matter.