Themed collection In celebration of the Lunar New Year, 2026
Engineering live cell surfaces with polyphenol-functionalized nanoarchitectures
Polyphenol-functionalized nanoarchitectures (cytoPNAs) provide a modular and cell independent strategy to create biohybrids for cell engineering, with improved production for biomanufacturing and enhanced efficacy for cell-based therapies.
Chem. Sci., 2025,16, 3774-3787
https://doi.org/10.1039/D4SC07198K
Covalent/metal–organic framework membranes with tailored pore functionality for accurate ion separation
Engineering covalent organic framework/metal–organic framework membranes (COFMs/MOFMs) with precisely tailored dimensions and functionalities is a promising solution for achieving high-precision ion separation in multicomponent coexisting systems.
Chem. Sci., 2025,16, 22900-22932
https://doi.org/10.1039/D5SC07238G
Critical issues and optimization strategies of vanadium dioxide-based cathodes towards high-performance aqueous Zn-ion batteries
Aqueous zinc-ion batteries (AZIBs) are gaining significant attention due to their excellent safety, cost-effectiveness, and environmental friendliness, making them highly competitive energy storage solutions.
Chem. Sci., 2025,16, 8217-8239
https://doi.org/10.1039/D5SC01889G
A review of machine learning methods for imbalanced data challenges in chemistry
Imbalanced data, where certain classes are significantly underrepresented in a dataset, is a widespread machine learning (ML) challenge across various fields of chemistry, yet it remains inadequately addressed.
Chem. Sci., 2025,16, 7637-7658
https://doi.org/10.1039/D5SC00270B
Hierarchical interface engineering for advanced magnesium-based hydrogen storage: synergistic effects of structural design and compositional modification
Interface engineering fundamentally revolutionizes magnesium-based hydrogen storage systems by orchestrating atomic-scale interactions and mass transport pathways through synergistic integration of structural design and compositional modification.
Chem. Sci., 2025,16, 7610-7636
https://doi.org/10.1039/D5SC01169H
Status and outlook of solid electrolyte membrane reactors for energy, chemical, and environmental applications
This article provides a comprehensive overview of the progress, challenges, and outlook of solid electrolyte membrane reactors (SEMRs) in energy, chemical, and environmental applications.
Chem. Sci., 2025,16, 6620-6687
https://doi.org/10.1039/D4SC08300H
Bimetallic effects in carbon dioxide electroreduction
This review systematically summarizes the latest advances in bimetallic effects for the reduction of CO2 to multi-carbon products, discussing the structure–activity relationships of typical bimetallic catalysts for the reaction.
Chem. Sci., 2025,16, 5413-5446
https://doi.org/10.1039/D5SC00670H
Biomass-derived carbon dots: synthesis, modification and application in batteries
The review aims to offer a comprehensive overview of the advancements made in harnessing BCDs for electrochemical energy storage applications.
Chem. Sci., 2025,16, 4937-4970
https://doi.org/10.1039/D4SC08659G
Effects of oxygen vacancies on hydrogenation efficiency by spillover in catalysts
The hydrogenation efficiency by spillover in catalysts affected by oxygen vacancy through hydrogen dissociation, hydrogen spillover, and hydrogenation processes is presented. This review summarize insights for developing high efficiency catalysts.
Chem. Sci., 2025,16, 3408-3429
https://doi.org/10.1039/D4SC07375D
Phosphor-converted light-emitting diodes in the marine environment: current status and future trends
This review delves into the application of phosphor-converted light-emitting diodes (pc-LEDs) in underwater optical communication and marine fishery, exploring the development strategies of phosphors tailored for the marine environment.
Chem. Sci., 2025,16, 2089-2104
https://doi.org/10.1039/D4SC06605G
Chemical modulation and defect engineering in high-performance GeTe-based thermoelectrics
The crystal structure, chemical bonding characteristics, band structure, and phonon dynamics of GeTe are revealed to elucidate the underlying mechanisms that contribute to its exceptional performance.
Chem. Sci., 2025,16, 1617-1651
https://doi.org/10.1039/D4SC06615D
Intramolecular exciton coupling modulates the convergent singlet-triplet energy gap toward NIR-emissive heavy-atom-free Oligo-BODIPY photosensitizers
This work establishes intramolecular exciton coupling in conjugated β,β-linked BODIPY oligomers (up to tetramer) as a versatile strategy to design heavy-atom-free photosensitizers with simultaneous NIR emission and long-lived triplet states.
Chem. Sci., 2026,17, 3267-3277
https://doi.org/10.1039/D5SC08201C
Realizing highly efficient electrofluorescence through a co-axial hybrid local and charge-transfer (HLCT) excited state
Two highly efficient electrofluorescent materials with co-axial HLCT excited states are investigated. A maximum EQE of up to 14.8% is achieved due to the high PLQY of 81% and efficient triplet utilization in the OLEDs based on these materials.
Chem. Sci., 2025,16, 22679-22689
https://doi.org/10.1039/D5SC06557G
High-entropy sulfide nanoflowers with multi-atomic catalytic sites for efficient nitrate-to-ammonia conversion
A hollow spherical-flower NiCoFeV–S high-entropy sulfide is synthesized via a mild hydrothermal method. The NiCoFeV–S exhibits exceptional bifunctional performance for nitrate reduction reaction (NO3RR) and oxygen evolution reaction (OER).
Chem. Sci., 2025,16, 18298-18308
https://doi.org/10.1039/D5SC04536C
Unlocking the potential of a multi-electron p-type polyheterocycle cathode: when it meets a small-size and high-charge anion
A multi-electron p-type polyheterocycle cathode compatible with the small-size and high-charge SO42− anion unlocks high utilization (99.5%) of phenothiazine/piperazine units with ultralow activation energy (0.20 eV) for better Zn-organic batteries.
Chem. Sci., 2025,16, 16542-16551
https://doi.org/10.1039/D5SC05022G
Regulation of charge carrier transportation in D–π–A type covalent organic frameworks for promoting photocatalytic H2O2 production
The four D–π–A type COFs with different electron-withdrawing units (N-heterocycles) can regulate the transportation of photogenerated charge carriers.
Chem. Sci., 2025,16, 16668-16677
https://doi.org/10.1039/D5SC02875B
AIQM2: organic reaction simulations beyond DFT
AIQM2's high speed, competitive accuracy, and robustness enable organic reaction simulations beyond what is possible with the popular DFT methods. It can be used for TS structure search and reactive dynamics, often with chemical accuracy.
Chem. Sci., 2025,16, 15901-15912
https://doi.org/10.1039/D5SC02802G
Spin polarization induced rapid reconstruction of transition metal oxide for efficient water electrolysis
The modulation of Co orbital filling lowers the energy barrier for the Co2+ to Co3+ reconstruction process, facilitating the adsorption/desorption equilibrium of the *OOH in the OER for enhanced efficiency of interfacial electron transfer.
Chem. Sci., 2025,16, 14750-14759
https://doi.org/10.1039/D5SC04336K
Electrochemically promoted defluorinative sulfoximination and fluorosulfonylation of non-activated aryl fluorides at room temperature
The first defluorinative sulfoximination and fluorosulfonylation of non-activated aryl fluorides at room temperature has been achieved.
Chem. Sci., 2025,16, 14161-14169
https://doi.org/10.1039/D5SC03674G
Molecular engineering of bis(triphenylamine)-modified fluorene luminophore for immensely enriching anisotropic force-triggered high-contrast tricolor fluorescent molecular switches library
Eight new anisotropic force-triggered high-contrast tricolor fluorescent molecular switches are developed via a high-efficiency molecular engineering strategy. Furthermore, three advanced high-security anticounterfeiting systems are constructed.
Chem. Sci., 2025,16, 12293-12302
https://doi.org/10.1039/D5SC02314A
Copper-catalyzed asymmetric carbonylative hydroallylation of vinylarenes
An efficient copper-catalyzed carbonylative hydroallylation of vinylarenes has been developed using carbon monoxide as the C1 source.
Chem. Sci., 2025,16, 10951-10956
https://doi.org/10.1039/D5SC02421H
Interfacial engineering of a nanofibrous Ru/Cr2O3 heterojunction for efficient alkaline/acid-universal hydrogen evolution at the ampere level
A nanofibrous Ru/Cr2O3 heterojunction is fabricated to modulate the electronic structure of Ru for improving *H desorption, exhibiting exceptional alkaline/acid-universal hydrogen evolution performance at ampere-grade current density.
Chem. Sci., 2025,16, 10042-10050
https://doi.org/10.1039/D5SC00248F
A novel fully conjugated COF adorned on 3D-G to boost the “D–π–A” electron regulation in oxygen catalysis performance
The BI groups in PBIPorCo transfer electrons to the Co–N4 site as a “D–π–A” structure, which enhances the cloud density. The “π–π interactions”.
Chem. Sci., 2025,16, 9951-9965
https://doi.org/10.1039/D5SC02082D
Exploring a solid-state nanopore approach for single-molecule protein detection from single cells
This study presents a solid-state nanopore approach for single-molecule protein detection from single cells, utilizing a nanopore electrophoretic driver protein to enhance target protein capture efficiency and analyze protein conformational changes.
Chem. Sci., 2025,16, 8501-8508
https://doi.org/10.1039/D5SC01764E
Umpolung of a covalent organic framework for high-performance cathodic sodium ion storage
Umpolung of the typical p-type TPA into n-type ATTO contributes to the COF electrode with a remarkable cathodic capacity of 286.31 mA h g−1 at a current density of 0.1 A g−1 in SIBs.
Chem. Sci., 2025,16, 7711-7719
https://doi.org/10.1039/D5SC01195G
Fe doping intensifies the built-in electric field for tailoring the reconstruction of sulfides towards efficient oxygen evolution
The built-in electric field enhanced by Fe doping stabilizes the reconstruction process of sulfides and triggers the lattice oxygen mediated mechanism of Fe–NiOOH, ultimately enabling efficient electrocatalytic oxygen evolution.
Chem. Sci., 2025,16, 7467-7476
https://doi.org/10.1039/D4SC08789E
A Mn–Rh dual single-atom catalyst for inducing C–C cleavage: relay catalysis reversing chemoselectivity in C–H oxidation
We developed a Mn, Rh DSAC (Mn1–Rh1@O-TiC) with high efficiency for cumene oxidation, enabling effective AP production. This work offers key insights into designing catalytic systems for organic tandem reactions from an inorganic chemistry aspect.
Chem. Sci., 2025,16, 7329-7338
https://doi.org/10.1039/D4SC08658A
A dual-enzyme activated fluorescent probe for precise identification of tumor senescence
We developed a dual-channel fluorescent probe (HDQ-NA-AFU-Gal) for the simultaneous and non-interfering detection of β-galactosidase and α-L-fucosidase for accurate identification of senescent cells.
Chem. Sci., 2025,16, 6507-6514
https://doi.org/10.1039/D5SC00103J
Bipyridine covalent organic framework aerogel for highly selective recovery of palladium in wastewater
A covalent organic framework chitosan aerogel was prepared and demonstrated high efficiency for selective Pd(II) recovery from wastewater.
Chem. Sci., 2025,16, 5745-5754
https://doi.org/10.1039/D4SC08674K
3D printable organic room-temperature phosphorescent materials and printed real-time sensing and display devices
3D printable RTP resins were constructed by doping the emissive guest molecules into methyl methacrylate. Accordingly, 3D-printable real-time temperature sensing and new-concept displays were fabricated through DLP 3D printing.
Chem. Sci., 2025,16, 5299-5309
https://doi.org/10.1039/D5SC00316D
Donor modulation brings all-in-one phototheranostics for NIR-II imaging-guided type-I photodynamic/photothermal synergistic cancer therapy
A novel all-in-one phototheranostics OTAB was synthesized by modifying the donor and regulating the band gap for NIR-II imaging-guided synergistic type-I PDT/PTT therapy.
Chem. Sci., 2025,16, 5089-5098
https://doi.org/10.1039/D4SC08685F
Silver-mediated formal [4π + 2σ] cycloaddition reactions of bicyclobutanes with nitrile imines: access to 2,3-diazobicyclo[3.1.1]heptenes
We disclose a method for silver-enabled formal [4π + 2σ] cycloaddition reactions between bicyclobutanes and nitrile imines (generated from hydrazonyl chlorides) to furnish a diverse array of 2,3-diazo-BCHepes.
Chem. Sci., 2025,16, 4654-4660
https://doi.org/10.1039/D4SC08280J
Novel supramolecular artificial light-harvesting systems based on AIE-active macrocycles for efficient white-light photocatalysis in water
A novel rigid macrocycle with aggregation-induced emission (AIE) properties was facilely synthesized to construct efficient artificial light-harvesting systems for photocatalysis through the Förster resonance energy transfer process.
Chem. Sci., 2025,16, 4741-4748
https://doi.org/10.1039/D4SC07689C
“All-four-in-one”: a novel mercury tellurite–nitrate Hg3(TeO3)(Te3O7)(NO3)2 exhibiting exceptional optical anisotropy
The novel mercury-based tellurite–nitrate Hg3(TeO3)(Te3O7)(NO3)2 possesses a unique [(Hg3Te4O10)2+]∞ layered structure and exhibits the highest birefringence in tellurite–nitrates.
Chem. Sci., 2025,16, 4749-4754
https://doi.org/10.1039/D4SC08166H
Catalysis of a LiF-rich SEI by aromatic structure modified porous polyamine for stable all-solid-state lithium metal batteries
POP fillers containing aromatic groups with internal π–π effect can catalyze the decomposition of LiTFSI to form a stable LiF-rich SEI layer and inhibit the growth of lithium dendrites, which helps the stable cycle of PEO-based solid-state batteries.
Chem. Sci., 2025,16, 2453-2464
https://doi.org/10.1039/D4SC07449A
Tuning the interlayer stacking of a vinylene-linked covalent organic framework for enhancing sacrificial agent-free hydrogen peroxide photoproduction
This work reports an efficient strategy to tailor the stacking mode in 2D vinylene-linked covalent triazine frameworks by regulating the base-catalyst with different alkali-metal ions.
Chem. Sci., 2025,16, 2215-2221
https://doi.org/10.1039/D4SC06451H
About this collection
In celebration of Chinese New Year, we are delighted to present a special collection of articles by authors in China. This collection of articles highlights popular contributions from China in a range of fields including energy storage, catalysis, material science, analytical chemistry, chemical biology, and machine learning.
We would like to wish everyone a Happy Year of the Horse!