RSC Advances  

The dihydrobenzofuran scaffolds demonstrate a wide range of biological activities. Several transition metals have been employed as catalysts for the efficacious synthesis of these structurally important frameworks.

3-Carboxamide indazoles have been developed using the amide coupling process. Density function theory (DFT) computations, and the assessment of binding energy using Auto Dock, illustrate the pharmaceutical effectiveness.

Starch as catalyst for organic reactions.

Bicyclic guanidines are utilized in organic synthesis as base catalysts or reagents.

This review article highlights the use of Betti base derivatives in transformation reactions for synthesizing organic compounds, particularly heterocyclic molecules, and investigation into their pharmacological properties.

Readily available and bench stable catalyst. Tolerates a variety of functional groups including orthogonal functionality. Circumvents the limitations of sp³ C–H borylation.

Among the diverse natural catalysts, caffeine has emerged as a green, expedient, non-toxic, and biodegradable catalyst. The main objective of this review is to present the existing knowledge pertaining to the exploitation of caffeine in various organic transformations.

The efficacy of green solvents and neat conditions in organocatalysed reactions were investigated. The results suggest cyclopentyl methyl ether and neat conditions could serve as alternatives, potentially enhancing the processes' sustainability.

Depression is one of the most mutilating conditions in the world today.

Dicyanobenzothiadiazole based dyes have shown exceptional tunability of oxidizing strength and absorption energy. The photophysical thermodynamic and kinetic properties are studied with desirable properties shown for future use in photocatalysis.

A scalable and selective N1-alkylation of indazoles broad in scope and suitable for manufacturing scale.

A variety of bioactive compounds can be synthesized via C–C and C–X (X = O/S/N/Se/Cl/Br) bond formation using an efficient catalytic system I₂/DMSO. This review highlights the progress and identifies potential paths for future research in this field.

Spiro heterocycle frameworks are a class of organic compounds that possesses unique structural features making them highly sought-after targets in drug discovery due to their diverse biological and pharmacological activities.

In this review, we discussed about clay based heterogeneous catalysts used for carbon–nitrogen bond formation.

A practical and sustainable metal-, additive-free olefination approach is proposed for the facile synthesis of various N-heteroazaarenes with high regioselectivity from simple methyl-substituted heteroarenes and amines using air as the oxidant.

Photocatalysis has proven to be an effective approach for the production of reactive intermediates under moderate reaction conditions.

Macrocycles play a pivotal and indispensable role within the realms of both medicine and industry.

Bis(3-indolyl)methanes (BIMs) are known for their important bioactivities, which include anti-cancer, anti-inflammatory, antibacterial, and antioxidant properties.

Multicomponent polymerization (MCP) is an innovative field related to polymer-based chemistry that offers numerous advantages derived from multicomponent reactions (MCRs). One of the key advantages of MCP is its ability to achieve high efficiency.

The reactions and mechanisms of alkynes that are involved in multi-component reactions through C–C and C–H positions are investigated.

A continuous production of nicotinamide derivatives was performed for the first time by exploiting the continuous-flow microreactors coupled with enzymes.

Enzymatic acylation of the flavonoid disaccharide rutin was achieved using Candida antarctica lipase B. Lipophilicity of the rutin esters produced increased with increasing alkyl chain length, yet antioxidant properties were unaffected.

The utilization of NH-1,2,3-triazoles as easily accessible building blocks in denitrogenative ring cleavage transformations with electrophiles to provide multifunctionalized nitrogen heterocycles and N-alkenyl compounds is reviewed.

The purpose of this review is to summarize the current literature on reductive C–N coupling of nitro compounds and boronic acids, with special emphasis on the mechanistic features of the reactions.

Two methods of computer simulation and experiments were used to explore the difference of primary hydroxyl groups in iridoid glycosides, which indicate that the chemical reactivity of hydroxyl at C10-position is higher than that of the C6′-position.