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Themed collection Journal of Materials Chemistry B Emerging Investigators

29 items
Profile

Journal of Materials Chemistry B profiles: Contributors to the Emerging Investigators 2018 issue

Journal of Materials Chemistry B profiles contributors to the Emerging Investigators issue.

Graphical abstract: Journal of Materials Chemistry B profiles: Contributors to the Emerging Investigators 2018 issue
Highlight

Gel-based soft actuators driven by light

Gels that display light-induced motile, life-like actions are reviewed and their potential applications as light-driven soft actuators are also discussed.

Graphical abstract: Gel-based soft actuators driven by light
Highlight

The benefits of macromolecular hydrogen sulfide prodrugs

The potential of H2S can be realised with design of macromolecular prodrugs.

Graphical abstract: The benefits of macromolecular hydrogen sulfide prodrugs
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Bioelectronics goes 3D: new trends in cell–chip interface engineering

Bioelectronic platforms can be used for electrophysiology, monitoring and stimulating specific cellular functions.

Graphical abstract: Bioelectronics goes 3D: new trends in cell–chip interface engineering
From the themed collection: Recent Review Articles
Highlight

Near-infrared light triggered drug release from mesoporous silica nanoparticles

Stimuli triggered drug delivery systems enable controlled release of drugs at the optimal space and time, thus achieving optimal therapeutic effects.

Graphical abstract: Near-infrared light triggered drug release from mesoporous silica nanoparticles
From the themed collection: Recent Review Articles
Highlight

Enhancing the sensitivity of colorimetric lateral flow assay (CLFA) through signal amplification techniques

This article highlights recent signal amplification techniques for enhancing the detection sensitivity of colorimetric lateral flow assay.

Graphical abstract: Enhancing the sensitivity of colorimetric lateral flow assay (CLFA) through signal amplification techniques
From the themed collection: Recent Review Articles
Review Article

Mechanical determination of particle–cell interactions and the associated biomedical applications

Mechanical determination of particle–cell interactions and the associated biomedical applications.

Graphical abstract: Mechanical determination of particle–cell interactions and the associated biomedical applications
From the themed collection: Recent Review Articles
Review Article

Bioelectronics with nanocarbons

Smart bioelectronics fabricated from nanocarbons have the potential to enable seamless integration with electrogenic cells and tissues.

Graphical abstract: Bioelectronics with nanocarbons
From the themed collection: Recent Review Articles
Review Article

Nanostructured interfaces for probing and facilitating extracellular electron transfer

Probing and facilitating microbial extracellular electron transfer through nanotechnology enabled platforms are transforming bioenergetic, bioelectronic, and other related research areas.

Graphical abstract: Nanostructured interfaces for probing and facilitating extracellular electron transfer
From the themed collection: Recent Review Articles
Communication

Design and fabrication of reduction-sensitive cell penetrating nanofibers for enhanced drug efficacy

In this work, we report the facile preparation of reduction-responsive cell penetrating nanofibers through the design and self-assembly of integrated multidomain peptides that have tunable surface charges and nanostructures in response to a chemically reducing environment. Stimuli-responsive cell penetrating activity was demonstrated for improved drug efficacy in HeLa cell culture compared with the non-responsive nanofibers.

Graphical abstract: Design and fabrication of reduction-sensitive cell penetrating nanofibers for enhanced drug efficacy
Paper

Polymeric arsenicals as scaffolds for functional and responsive hydrogels

Here arsenohydrogels are introduced for the first time as functional, tuneable and responsive hydrogels.

Graphical abstract: Polymeric arsenicals as scaffolds for functional and responsive hydrogels
Open Access Paper

Tuning HIV drug release from a nanogel-based in situ forming implant by changing nanogel size

This paper reports an in situ forming implant based on responsive nanogels that gives tuneable long-acting drug release.

Graphical abstract: Tuning HIV drug release from a nanogel-based in situ forming implant by changing nanogel size
Paper

An injectable dipeptide–fullerene supramolecular hydrogel for photodynamic antibacterial therapy

An injectable dipeptide–fullerene supramolecular hydrogel is designed for photodynamic antibacterial therapy.

Graphical abstract: An injectable dipeptide–fullerene supramolecular hydrogel for photodynamic antibacterial therapy
Paper

Reversible encapsulations and stimuli-responsive biological delivery from a dynamically assembled cucurbit[7]uril host and nanoparticle guest scaffold

Dynamic host–guest scaffold utilizes bioorthogonal small molecule to achieve therapeutic control.

Graphical abstract: Reversible encapsulations and stimuli-responsive biological delivery from a dynamically assembled cucurbit[7]uril host and nanoparticle guest scaffold
Paper

Pharmaceutical crystallization in surface-modified nanocellulose organogels

This study shows that it is possible to shift the polymorph of pharmaceuticals through crystallization in a nanocellulose gel. This is a demonstration of using natural materials that are readily surface modified to form a tailored environment for drug crystallization.

Graphical abstract: Pharmaceutical crystallization in surface-modified nanocellulose organogels
Paper

Lipid nanoemulsion passive tumor accumulation dependence on tumor stage and anatomical location: a new mathematical model for in vivo imaging biodistribution studies

Nanoparticle delivery to tumor tissue is one of the most important applications of nanomedicine.

Graphical abstract: Lipid nanoemulsion passive tumor accumulation dependence on tumor stage and anatomical location: a new mathematical model for in vivo imaging biodistribution studies
Open Access Paper

Barcoding chemical modifications into nucleic acids improves drug stability in vivo

The efficacy of nucleic acid therapies can be limited by unwanted degradation.

Graphical abstract: Barcoding chemical modifications into nucleic acids improves drug stability in vivo
Paper

Binding of an amphiphilic phthalocyanine to pre-formed liposomes confers light-triggered cargo release

Liposomes are able to load a range of cargos and have been used for drug delivery applications, including for stimuli-triggered drug release.

Graphical abstract: Binding of an amphiphilic phthalocyanine to pre-formed liposomes confers light-triggered cargo release
Paper

Enhancing anti-thrombogenicity of biodegradable polyurethanes through drug molecule incorporation

An anti-thrombogenic, elastic, biodegradable polyurethane with covalently incorporated drug can reduce blood platelet deposition on the surface.

Graphical abstract: Enhancing anti-thrombogenicity of biodegradable polyurethanes through drug molecule incorporation
Open Access Paper

Sub-zero temperature mechanically stable low molecular weight hydrogels

We show here a low molecular weight hydrogelator based on a functionalised dipeptide which is stable down to temperatures of −12 °C despite being made from >99% water. With the addition of glycerol this can be lowered further to −40 °C. At these colder temperatures there is no effect on the mechanical properties of the gels.

Graphical abstract: Sub-zero temperature mechanically stable low molecular weight hydrogels
Paper

Plasmonic Janus hybrids for the detection of small metabolites

Janus hybrids with amphiphilic structures were used for the sensitive detection of small metabolites.

Graphical abstract: Plasmonic Janus hybrids for the detection of small metabolites
Paper

A biodegradable polyphosphoester-functionalized poly(disulfide) nanocarrier for reduction-triggered intracellular drug delivery

A reduction-cleavable polyphosphoester-functionalized poly(disulfide) nanoparticle has been constructed for the intracellular triggered release of doxorubicin in tumor chemotherapy.

Graphical abstract: A biodegradable polyphosphoester-functionalized poly(disulfide) nanocarrier for reduction-triggered intracellular drug delivery
Paper

Biomolecular dynamic covalent polymers for DNA complexation and siRNA delivery

Dynamic covalent polymers made from modified amino acids complex nucleic acids and deliver siRNA in living cells.

Graphical abstract: Biomolecular dynamic covalent polymers for DNA complexation and siRNA delivery
Paper

Quantum-dot-encapsulated core–shell barcode particles from droplet microfluidics

A new class of QD-encapsulated core–shell barcode particles for biomedical applications were generated using a capillary microfluidic device.

Graphical abstract: Quantum-dot-encapsulated core–shell barcode particles from droplet microfluidics
Paper

Highly selective, red emitting BODIPY-based fluorescent indicators for intracellular Mg2+ imaging

New fluorescent sensors with excellent turn-on ratio and low energy excitation provide Mg2+ detection in live cells with high selectivity.

Graphical abstract: Highly selective, red emitting BODIPY-based fluorescent indicators for intracellular Mg2+ imaging
Paper

Statistical versus block fluoropolymers in gene delivery

A statistical fluorocopolymer shows dramatically higher transfection efficiency in gene delivery than a block one.

Graphical abstract: Statistical versus block fluoropolymers in gene delivery
Paper

Self-immolative polymers with potent and selective antibacterial activity by hydrophilic side chain grafting

Self-immolative polymers, which exert potent antibacterial activity with low hemolytic toxicity to red blood cells, are triggered to unzip into small molecules by a chemical stimulus.

Graphical abstract: Self-immolative polymers with potent and selective antibacterial activity by hydrophilic side chain grafting
Paper

In vitro and in vivo toxicity evaluation of halloysite nanotubes

Halloysite is weakly toxic to cells and can be excreted out through the gastrointestinal metabolism of zebrafish.

Graphical abstract: In vitro and in vivo toxicity evaluation of halloysite nanotubes
Paper

Conductive silk–polypyrrole composite scaffolds with bioinspired nanotopographic cues for cardiac tissue engineering

Imparting electroconductive and nanotopographical cues to biodegradable silk–fibroin films enhanced the maturation of cultured human stem cell-derived cardiomyocytes.

Graphical abstract: Conductive silk–polypyrrole composite scaffolds with bioinspired nanotopographic cues for cardiac tissue engineering
29 items

About this collection

Journal of Materials Chemistry B is proud to present this themed issue highlighting 2018’s rising stars of materials chemistry research. This issue gathers the very best work from materials chemists in the early stages of their independent career.

Each contributor was recommended by experts in their fields as carrying out work with the potential to influence future directions in materials chemistry. Congratulations to all of those who feature on their important work so far in the field of materials for biology and medicine.


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