Metallomics: the history over the last decade and a future outlook
Hiroki Haraguchi discusses the history of metallomics over the last decade, and considers the current and future directions of the field.
Cross talk between neurometals and amyloidogenic proteins at the synapse and the pathogenesis of neurodegenerative diseases
Increasing evidence suggests that disruption of metal homeostasis contributes to the pathogenesis of various neurodegenerative diseases, including Alzheimer's disease, prion diseases, Lewy body diseases, and vascular dementia.
Biotransformation of organic selenium compounds in budding yeast, Saccharomyces cerevisiae
Organic selenium metabolites of plants and animals such as selenoamino acids and selenosugars are metabolized to selenomethionine in yeast.
A mitochondria-targeted fluorescent probe for selective detection of mitochondrial labile Fe(II)
Development of a turn-on and selective fluorescent probe for mitochondrial labile Fe(II).
Cardiac myoglobin participates in the metabolic pathway of selenium in rats
We demonstrated that cardiac myoglobin participates in the selenium metabolism in rat hearts.
Intra-electron transfer induced by protonation in copper-containing nitrite reductase
Electron transfer between two Cu sites in the enzyme induced by protonation of remote catalytic residues.
Calcium isotope signature: new proxy for net change in bone volume for chronic kidney disease and diabetic rats
Herein, we measure the Ca isotope ratios (44Ca/42Ca and 43Ca/42Ca) in serum and bone samples collected from rats with chronic kidney disease (CKD) or diabetes mellitus (DM).
About this collection
This is a collection of papers showcasing some of the best research from Japanese institutes in the field of metallomics and highlight some of the exciting research being conducted there. New articles will be added to this ongoing collection as they are published.