Themed collection Food & Function Review Articles 2022

59 items
Review Article

Milk exosomes: an oral drug delivery system with great application potential

Exosomes are extracellular vesicles with the smallest diameter, usually divided into cellular sources and body fluid sources.

Graphical abstract: Milk exosomes: an oral drug delivery system with great application potential
From the themed collection: Food & Function Review Articles 2022
Accepted Manuscript - Review Article

Regulatory effect of dietary nitrate on blood pressure: A meta-analysis of randomized controlled trials

From the themed collection: Food & Function Review Articles 2022
Review Article

Fruits and their phytochemicals in mitigating the ill effects of ionizing radiation: review on the existing scientific evidence and way forward

Although helpful in treating cancer, exposure to ionizing radiation can sometimes cause severe side effects, negating its benefit.

Graphical abstract: Fruits and their phytochemicals in mitigating the ill effects of ionizing radiation: review on the existing scientific evidence and way forward
From the themed collection: Food & Function Review Articles 2022
Accepted Manuscript - Review Article

Eriodictyol: a review of its pharmacological activities and molecular mechanisms related to ischemic stroke

From the themed collection: Food & Function Review Articles 2022
Accepted Manuscript - Review Article

Anticancer potential of lignans from flaxseed: metabolites, molecular target, synthetic lignan, current challenges and perspectives

From the themed collection: Food & Function Review Articles 2022
Open Access Review Article

Peptides and protein hydrolysates exhibiting anti-inflammatory activity: sources, structural features and modulation mechanisms

This work highlights the structure–activity relationship of anti-inflammatory peptides, estimates their in silico anti-inflammatory potential using bioactivity predictors and studies their presence in sustainable protein sources.

Graphical abstract: Peptides and protein hydrolysates exhibiting anti-inflammatory activity: sources, structural features and modulation mechanisms
From the themed collection: Food & Function Review Articles 2022
Review Article

Recent advances in polysaccharides from Rose roxburghii Tratt fruits: isolation, structural characterization, and bioactivities

Rosa roxburghii Tratt fruit (RRF), known commonly as Cili in China, is a highly valued fruit that contains abundant functional and nutritional constituents with a variety of health-promoting benefits.

Graphical abstract: Recent advances in polysaccharides from Rose roxburghii Tratt fruits: isolation, structural characterization, and bioactivities
From the themed collection: Food & Function Review Articles 2022
Review Article

Dietary intervention in depression – a review

Probiotics, micronutrients and other active substances by regulating the pathways such as tryptophan metabolism and inflammation showed significant antidepressant effects. These provide insights for developing antidepressant foods.

Graphical abstract: Dietary intervention in depression – a review
From the themed collection: Food & Function Review Articles 2022
Review Article

Potential role of dietary nitrate in relation to cardiovascular and cerebrovascular health, cognition, cognitive decline and dementia: a review

Evidence is accumulating for improved cardiovascular health with dietary nitrate intake. This review identifies and discusses the potential for nitrate to improve cognitive function and markers of brain health, and to reduce risk of dementia.

Graphical abstract: Potential role of dietary nitrate in relation to cardiovascular and cerebrovascular health, cognition, cognitive decline and dementia: a review
From the themed collection: Food & Function Review Articles 2022
Review Article

Association of dietary meat consumption habits with neurodegenerative cognitive impairment: an updated systematic review and dose–response meta-analysis of 24 prospective cohort studies

The association between dietary meat consumption habits and neurodegenerative cognitive impairment (NCI) has been made but recent studies have reported controversial results.

Graphical abstract: Association of dietary meat consumption habits with neurodegenerative cognitive impairment: an updated systematic review and dose–response meta-analysis of 24 prospective cohort studies
From the themed collection: Food & Function Review Articles 2022
Review Article

The effect of structure and preparation method on the bioactivity of polysaccharides from plants and fungi

Polysaccharides are not only the main components in the cell walls of plants and fungi, but also a structure that supports and protects cells.

Graphical abstract: The effect of structure and preparation method on the bioactivity of polysaccharides from plants and fungi
From the themed collection: Food & Function Review Articles 2022
Review Article

Self-assembled glycyrrhetinic acid derivatives for functional applications: a review

Glycyrrhetinic acid (GA), a famous natural product, has attracted much more attention because of its remarkable biological activity, natural sweetness, and good biocompatibility.

Graphical abstract: Self-assembled glycyrrhetinic acid derivatives for functional applications: a review
From the themed collection: Food & Function Review Articles 2022
Review Article

Does chronic consumption of orange juice improve cardiovascular risk factors in overweight and obese adults? A systematic review and meta-analysis of randomized controlled trials

This is the first meta-analysis that investigates the effects of chronic consumption of orange juice on cardiovascular risk factors in overweight and obese adults, demonstrating beneficial effects on blood pressure and HDL-C.

Graphical abstract: Does chronic consumption of orange juice improve cardiovascular risk factors in overweight and obese adults? A systematic review and meta-analysis of randomized controlled trials
From the themed collection: Food & Function Review Articles 2022
Review Article

Immunomodulatory effects and associated mechanisms of Momordica charantia and its phytochemicals

Momordica charantia L. (M. charantia), which is a member of the Cucurbitaceae family and widely distributed in tropical and subtropical regions, has been consumed as a vegetable and also used as herbal medicine for thousands of years worldwide.

Graphical abstract: Immunomodulatory effects and associated mechanisms of Momordica charantia and its phytochemicals
From the themed collection: Food & Function Review Articles 2022
Review Article

Effects of curcumin, a bioactive component of turmeric, on type 2 diabetes mellitus and its complications: an updated review

Effects of Curcumin in Type 2 Diabetes Mellitus (T2DM).

Graphical abstract: Effects of curcumin, a bioactive component of turmeric, on type 2 diabetes mellitus and its complications: an updated review
From the themed collection: Food & Function Review Articles 2022
Review Article

A comprehensive review on lactoferrin: a natural multifunctional glycoprotein

Health benifts and appplication of lactoferrin.

Graphical abstract: A comprehensive review on lactoferrin: a natural multifunctional glycoprotein
From the themed collection: Food & Function Review Articles 2022
Review Article

Dietary fiber ameliorates sleep disturbance connected to the gut–brain axis

Circadian rhythms play an important role in maintaining normal physiological and psychological functions of the body, including regulating sleep patterns.

Graphical abstract: Dietary fiber ameliorates sleep disturbance connected to the gut–brain axis
From the themed collection: Food & Function Review Articles 2022
Review Article

Effects of pectins on colorectal cancer: targeting hallmarks as a support for future clinical trials

The intake of dietary fibers has been associated with a reduction in the risk of colorectal cancer.

Graphical abstract: Effects of pectins on colorectal cancer: targeting hallmarks as a support for future clinical trials
From the themed collection: Food & Function Review Articles 2022
Review Article

|Therapeutic and preventive effects of apigenin in cerebral ischemia: a review

APG can exert various protective effects against cerebral ischemia. Moreover, APG has shown a highly promising ability to prevent cerebral ischemia in terms of regulating blood glucose, blood pressure, lipids and gut microbes.

Graphical abstract: |Therapeutic and preventive effects of apigenin in cerebral ischemia: a review
From the themed collection: Food & Function Review Articles 2022
Review Article

Algal polysaccharides and derivatives as potential therapeutics for obesity and related metabolic diseases

The potential and challenges of algal polysaccharides and their derivatives as potential therapeutic agents for obesity and its related metabolic diseases.

Graphical abstract: Algal polysaccharides and derivatives as potential therapeutics for obesity and related metabolic diseases
From the themed collection: Food & Function Review Articles 2022
Open Access Review Article

Biological effects of the olive tree and its derivatives on the skin

The olive tree and its derivatives are of great interest in the field of biomedicine due to their numerous health properties.

Graphical abstract: Biological effects of the olive tree and its derivatives on the skin
From the themed collection: Food & Function Review Articles 2022
Open Access Review Article

Structure, controlled release mechanisms and health benefits of pectins as an encapsulation material for bioactive food components

Depending on the chemical structure pectin may serve as protective shell material and as a prebiotic.

Graphical abstract: Structure, controlled release mechanisms and health benefits of pectins as an encapsulation material for bioactive food components
From the themed collection: Food & Function Review Articles 2022
Review Article

Potential of food-derived bioactive peptides in alleviation and prevention of Alzheimer's disease

Memory and cognitive impairment are the principal clinical symptoms of Alzheimer's disease (AD).

Graphical abstract: Potential of food-derived bioactive peptides in alleviation and prevention of Alzheimer's disease
From the themed collection: Food & Function Review Articles 2022
Review Article

Toxicity of zearalenone and its nutritional intervention by natural products

Zearalenone (ZEN) can cause endocrine-disrupting effects, as well as oxidative damage and other hazards that can lead to systemic toxic effects. Natural compounds as dietary supplements can effectively alleviate the ZEN-induced toxic effects.

Graphical abstract: Toxicity of zearalenone and its nutritional intervention by natural products
From the themed collection: Food & Function Review Articles 2022
Review Article

Cactaceae plants as sources of active bioavailable phytochemicals

Cactaceous plants are sources of bioaccessible and bioavailable phytochemicals with potent bioactivities and compelling potential for the development of functional and nutraceutical foods, but their use as therapeutic agents deserves further study.

Graphical abstract: Cactaceae plants as sources of active bioavailable phytochemicals
From the themed collection: Food & Function Review Articles 2022
Review Article

Natural polyphenols: a potential prevention and treatment strategy for metabolic syndrome

Natural polyphenols from different plants (including vegetables, fruits, cocoa beans, teas and herbs) can be used to reduce the symptoms of metabolic syndrome (MS).

Graphical abstract: Natural polyphenols: a potential prevention and treatment strategy for metabolic syndrome
From the themed collection: Food & Function Review Articles 2022
Review Article

Antioxidant and anti-inflammatory protective effects of yellowtail (Seriola quinqueradiata) milt hydrolysates on human intestinal epithelial cells in vitro and dextran sodium sulphate-induced mouse colitis in vivo

Yellowtail milt hydrolysates have considerable antioxidant and anti-inflammatory efficacies to maintain gut health.

Graphical abstract: Antioxidant and anti-inflammatory protective effects of yellowtail (Seriola quinqueradiata) milt hydrolysates on human intestinal epithelial cells in vitro and dextran sodium sulphate-induced mouse colitis in vivo
From the themed collection: Food & Function Review Articles 2022
Review Article

Potential roles and molecular mechanisms of phytochemicals against cancer

Increasing evidence has been reported regarding phytochemicals, plant secondary metabolites, having therapeutic functions against numerous human diseases.

Graphical abstract: Potential roles and molecular mechanisms of phytochemicals against cancer
From the themed collection: Food & Function Review Articles 2022
Review Article

The adverse effect of heat stress and potential nutritional interventions

Protein, vitamin, trace element and electrolyte can mitigate heat damage by enhancing the antioxidant system and immune function, promoting heat shock protein expression, and suppressing inflammatory responses.

Graphical abstract: The adverse effect of heat stress and potential nutritional interventions
From the themed collection: Food & Function Review Articles 2022
Review Article

A critical review of ginkgolic acids in Ginkgo biloba leaf extract (EGb): toxicity and technologies to remove ginkgolic acids and their promising bioactivities

Ginkgo biloba leaf extract (EGb) is high in bioactive components (over 170), which are used in food additives, medicine, cosmetics, health products, and other sectors.

Graphical abstract: A critical review of ginkgolic acids in Ginkgo biloba leaf extract (EGb): toxicity and technologies to remove ginkgolic acids and their promising bioactivities
From the themed collection: Food & Function Review Articles 2022
Review Article

Colon microbiota modulation by dairy-derived diet: new strategy for prevention and treatment of colorectal cancer

The modulation of the intestinal microbiota by dairy-derived product consumption is being explored as an innovative approach to fight colorectal cancer.

Graphical abstract: Colon microbiota modulation by dairy-derived diet: new strategy for prevention and treatment of colorectal cancer
From the themed collection: Food & Function Review Articles 2022
Review Article

Medicine–food herb: Angelica sinensis, a potential therapeutic hope for Alzheimer's disease and related complications

As a typical medicine–food herb, Angelica sinensis can alleviate AD and AD complications based on pharmaceutical material and dietary supply.

Graphical abstract: Medicine–food herb: Angelica sinensis, a potential therapeutic hope for Alzheimer's disease and related complications
From the themed collection: Food & Function Review Articles 2022
Review Article

Effects of oligosaccharides on the markers of glycemic control: a systematic review and meta-analysis of randomized controlled trials

This study is by far the most extensive systematic review to evaluate the role of oligosaccharides on markers of glycemic control. Meta-analysis revealed that oligosaccharide interventions can exert beneficial effects on FBG, FBI, HbA1c and HOMA-IR.

Graphical abstract: Effects of oligosaccharides on the markers of glycemic control: a systematic review and meta-analysis of randomized controlled trials
From the themed collection: Food & Function Review Articles 2022
Review Article

The effect of pro-/synbiotic supplementation on the brain-derived neurotrophic factor: a systematic review and meta-analysis of randomized controlled trials

We conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) to investigate the impact of pro-/synbiotic supplementation on brain-derived neurotrophic factor (BDNF) levels.

Graphical abstract: The effect of pro-/synbiotic supplementation on the brain-derived neurotrophic factor: a systematic review and meta-analysis of randomized controlled trials
From the themed collection: Food & Function Review Articles 2022
Review Article

Are isothiocyanates and polyphenols from Brassicaceae vegetables emerging as preventive/therapeutic strategies for NAFLD? The landscape of recent preclinical findings

Effects of the most abundant bioactive compounds (isothiocyanates and polyphenols) of Brassicaceae vegetables on the gut-liver-adipose axis, which is pivotal for nonalcoholic fatty lvier disease (NAFLD) emergence/progression.

Graphical abstract: Are isothiocyanates and polyphenols from Brassicaceae vegetables emerging as preventive/therapeutic strategies for NAFLD? The landscape of recent preclinical findings
From the themed collection: Food & Function Review Articles 2022
Review Article

Potentialities of Ginkgo extract on toxicants, toxins, and radiation: a critical review

Protective effect of Ginkgo biloba extract against toxins, toxicants and radiations.

Graphical abstract: Potentialities of Ginkgo extract on toxicants, toxins, and radiation: a critical review
From the themed collection: Food & Function Review Articles 2022
Review Article

Vitamin D resistant genes – promising therapeutic targets of chronic diseases

Vitamin D is an essential vitamin indispensable for calcium and phosphate metabolism, and its deficiency has been implicated in several extra-skeletal pathologies, including cancer and chronic diseases.

Graphical abstract: Vitamin D resistant genes – promising therapeutic targets of chronic diseases
From the themed collection: Food & Function Review Articles 2022
Review Article

Genus Spatholobus: a comprehensive review on ethnopharmacology, phytochemistry, pharmacology, and toxicology

Spatholobus plants are the valuable edible-medicinal herb which are mainly distributed in Asia, with complex chemical compositions and a wide spectrum of bioactive effects.

Graphical abstract: Genus Spatholobus: a comprehensive review on ethnopharmacology, phytochemistry, pharmacology, and toxicology
From the themed collection: Food & Function Review Articles 2022
Review Article

Targeting gut microbial bile salt hydrolase (BSH) by diet supplements: new insights into dietary modulation of human health

Dietary supplements could modulate the abundance of BSH-producing bacteria to regulate the BSH enzyme activity, thereby change the BAs composition to regulate FXR signaling, which then regulate human health.

Graphical abstract: Targeting gut microbial bile salt hydrolase (BSH) by diet supplements: new insights into dietary modulation of human health
From the themed collection: Food & Function Review Articles 2022
Open Access Review Article

Beneficial effects of psyllium on the prevention and treatment of cardiometabolic diseases

Psyllium, especially its husk, has been widely used in food products. This review summarized the potential mechanisms of it in the prevention and treatment of cardiometabolic diseases and its applications in food systems.

Graphical abstract: Beneficial effects of psyllium on the prevention and treatment of cardiometabolic diseases
From the themed collection: Food & Function Review Articles 2022
Review Article

Probiotics and gut microbiota: mechanistic insights into gut immune homeostasis through TLR pathway regulation

Consumption of probiotics as a useful functional food improves the host's wellbeing, and, when paired with prebiotics (indigestible dietary fibre/carbohydrate), often benefits the host through anaerobic fermentation.

Graphical abstract: Probiotics and gut microbiota: mechanistic insights into gut immune homeostasis through TLR pathway regulation
From the themed collection: Food & Function Review Articles 2022
Review Article

Bioactives and functional food ingredients with promising potential for the management of cerebral and myocardial ischemia: a comprehensive mechanistic review

Ischemia is a deadly disease with complex pathophysiology and has a limited number of drugs. A compilation of the mechanistic studies of food bioactives with multimodal actions and higher safety has been provided in this review.

Graphical abstract: Bioactives and functional food ingredients with promising potential for the management of cerebral and myocardial ischemia: a comprehensive mechanistic review
From the themed collection: Food & Function Review Articles 2022
Review Article

The role of functional oligosaccharides as prebiotics in ulcerative colitis

An overview of the definitions, functions, mechanisms and applications of functional oligosaccharides in colitis prevention and treatment.

Graphical abstract: The role of functional oligosaccharides as prebiotics in ulcerative colitis
From the themed collection: Food & Function Review Articles 2022
Open Access Review Article

Designing food for the elderly: the critical impact of food structure

In this review, after examining the physiological changes associated to food consumption in old age, the possible role of food structure in delivering target functionalities has been critically discussed.

Graphical abstract: Designing food for the elderly: the critical impact of food structure
From the themed collection: Food & Function Review Articles 2022
Review Article

Therapeutic effects of ginseng and ginsenosides on colorectal cancer

The possible anticancer mechanisms of ginsenoside.

Graphical abstract: Therapeutic effects of ginseng and ginsenosides on colorectal cancer
From the themed collection: Food & Function Review Articles 2022
Review Article

The impact of prebiotic fructooligosaccharides on gut dysbiosis and inflammation in obesity and diabetes related kidney disease

Mechanisms involved in obesity, diabetes and kidney dysfunction via exacerbation of inflammatory response and its association with gut dysbiosis, and role of FOS on improvement of gut dysbiosis and attenuation of inflammation in obesity and diabetes.

Graphical abstract: The impact of prebiotic fructooligosaccharides on gut dysbiosis and inflammation in obesity and diabetes related kidney disease
From the themed collection: Food & Function Review Articles 2022
Review Article

Probiotic Escherichia coli NISSLE 1917 for inflammatory bowel disease applications

Probiotic Escherichia coli Nissle 1917 (EcN) with different modifications has exhibited multiple superiorities in the prevention and treatment of inflammatory bowel disease.

Graphical abstract: Probiotic Escherichia coli NISSLE 1917 for inflammatory bowel disease applications
From the themed collection: Food & Function Review Articles 2022
Review Article

Effects of natural dihydrochalcones in sweet tea (Lithocarpus polystachyus) on diabetes: a systematical review and meta-analysis of animal studies

Sweet tea (Lithocarpus polystachyus Rehd.), a natural functional food highly rich in dihydrochalcones including trilobatin, phlorizin and phloretin, is reported to possess numerous biological activities especially for treating diabetes.

Graphical abstract: Effects of natural dihydrochalcones in sweet tea (Lithocarpus polystachyus) on diabetes: a systematical review and meta-analysis of animal studies
From the themed collection: Food & Function Review Articles 2022
Review Article

Dietary phenolic-type Nrf2-activators: implications in the control of toxin-induced hepatic disorders

Numerous studies have exemplified the importance of nuclear factor erythroid 2-related factor 2 (Nrf2) activation in the alleviation of toxin-induced hepatic disorders primarily through eliminating oxidative stress.

Graphical abstract: Dietary phenolic-type Nrf2-activators: implications in the control of toxin-induced hepatic disorders
From the themed collection: Food & Function Review Articles 2022
Review Article

Underlying evidence for the health benefits of fermented foods in humans

Fermented foods (FFs) have been a part of our diets for millennia and comprise highly diverse products obtained from plants and animals all over the world: Mechanisms of action and impact of health status.

Graphical abstract: Underlying evidence for the health benefits of fermented foods in humans
From the themed collection: Food & Function Review Articles 2022
Review Article

New red-fleshed apple cultivars: a comprehensive review of processing effects, (poly)phenol bioavailability and biological effects

This review details the first comprehensive overview of new hybrid red-fleshed apples, mainly focusing on their (poly)phenolic composition, the effect of processing, the (poly)phenolic bioavailability and the biological effects.

Graphical abstract: New red-fleshed apple cultivars: a comprehensive review of processing effects, (poly)phenol bioavailability and biological effects
From the themed collection: Food & Function Review Articles 2022
Review Article

The effect of quercetin on diabetic nephropathy (DN): a systematic review and meta-analysis of animal studies

Quercetin, a flavonoid possessing numerous biological activities, is reported to improve renal injury in diabetic animals.

Graphical abstract: The effect of quercetin on diabetic nephropathy (DN): a systematic review and meta-analysis of animal studies
From the themed collection: Food & Function Review Articles 2022
Review Article

Associating the blood vitamin A, C, D and E status with tuberculosis: a systematic review and meta-analysis of observational studies

The current meta-analysis suggested significantly lower blood vitamin A, D and E concentrations in the tuberculosis group than in the control group. The difference in the vitamin C status was inconclusive.

Graphical abstract: Associating the blood vitamin A, C, D and E status with tuberculosis: a systematic review and meta-analysis of observational studies
From the themed collection: Food & Function Review Articles 2022
Review Article

Protective effect of food derived nutrients on cisplatin nephrotoxicity and its mechanism

Platinum-based metal complexes, especially cisplatin (cis-diamminedichloroplatinum II, CDDP), possess strong anticancer properties and a broad anticancer spectrum.

Graphical abstract: Protective effect of food derived nutrients on cisplatin nephrotoxicity and its mechanism
From the themed collection: Food & Function Review Articles 2022
Review Article

Beneficial effects of blueberry supplementation on the components of metabolic syndrome: a systematic review and meta-analysis

Metabolic syndrome (MetS) is a combination of interconnected disorders that puts a heavy burden on society.

Graphical abstract: Beneficial effects of blueberry supplementation on the components of metabolic syndrome: a systematic review and meta-analysis
From the themed collection: Food & Function Review Articles 2022
Review Article

Dietary phytochemicals targeting Nrf2 for chemoprevention in breast cancer

Dietary phytochemicals play chemopreventive roles in breast cancer by activating Nrf2 signaling pathway.

Graphical abstract: Dietary phytochemicals targeting Nrf2 for chemoprevention in breast cancer
From the themed collection: Food & Function Review Articles 2022
Review Article

N-3 PUFAs and their specialized pro-resolving lipid mediators on airway inflammatory response: beneficial effects in the prevention and treatment of respiratory diseases

Respiratory diseases include a wide range of pathologies with different clinical manifestations, affecting the normal airways and lung function.

Graphical abstract: N-3 PUFAs and their specialized pro-resolving lipid mediators on airway inflammatory response: beneficial effects in the prevention and treatment of respiratory diseases
From the themed collection: Food & Function Review Articles 2022
Review Article

Development of the digestive system in early infancy and nutritional management of digestive problems in breastfed and formula-fed infants

Immature gastrointestinal tract and different composition between infant formula and human milk make mild digestive problems more likely to occur in formula-fed infants. Special infant formulas to manage the gastrointestinal problems are reviewed.

Graphical abstract: Development of the digestive system in early infancy and nutritional management of digestive problems in breastfed and formula-fed infants
From the themed collection: Food & Function Review Articles 2022
Paper

Ginsenoside compound K inhibits obesity-induced insulin resistance by regulation of macrophage recruitment and polarization via activating PPARγ

This study demonstrates that ginsenoside CK could improve insulin resistance by reducing inflammation through PPARγ/NF-κB signaling pathway, which implies that ginsenoside CK may be an effective agent against obesity or early diabetes.

Graphical abstract: Ginsenoside compound K inhibits obesity-induced insulin resistance by regulation of macrophage recruitment and polarization via activating PPARγ
From the themed collection: Food & Function Review Articles 2022
59 items

About this collection

This themed collection features recent review articles published in Food & Function.


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