Themed collection 2023 Pioneering Investigators

This review collectively discussed the utilisation of alcohols in various organic transformations and their application toward intermediates of drugs, drug derivatives and natural product-like molecules.

Steric indices are parameters used in chemistry to describe the spatial arrangement of atoms or groups of atoms in molecules.

Disintegrating multiple selectivity attributes through reversible steps provides excellent control over reaction parameters and precision in protein bioconjugation. This approach enables hypothesis-driven research in the field.

This review provides an overview of recent studies where optical and X-ray fluorescence imaging have been performed in combination in multimodal studies of cellular systems.

Over the past few decades, the advent of C–H activation has led to a rethink among chemists about the synthetic strategies employed for multi-step transformations.

This review provides a comprehensive overview of photothermal regulation strategies from fundamentals, criteria, and advanced materials to emerging applications.

This review discusses proton transfer kinetics for reactions involving transition metal hydride complexes, highlighting the techniques used to measure proton transfer rate constants and the implications for fuel-forming reactions.

Attempts to identify and probe atypical molecular aggregates focusing on the less explored null aggregates. The null aggregate was foretold by Kasha to possess null exciton interaction leading to spectroscopically uncoupled molecular assembly.

The development and strategies for covalently connected MOFs-polymers (including COFs) composites have summarized and reviewed along with their applications.

This review discusses the important role of silver(I) salts as additives in transition-metal catalyzed C–H activation, and depicts the discussion about the current shift towards Ag-free procedures, as plausible and sustainable alternatives.

Main group compounds react with azides leading to diverse N-containing molecules. In this review, the reactions of main group compounds with various azides are summarized, emphatically highlighting their reaction patterns and mechanisms.

Metal agents have made incredible strides in preclinical research and clinical applications, but their short emission/absorption wavelengths continue to be a barrier to their distribution, therapeutic action, visual tracking, and efficacy evaluation.

Chemical and electrochemical doping can strongly alter the electrical but also mechanical properties of conjugated polymers, which may enable new types of tunable materials and devices of interest for wearable electronics and bioelectronics.

This tutorial review explores the concepts of sustainable design and biodegradability, as applied to the design of synthetic polymers intended for use at scale.

Electrochemical hydrogenation reactions hold the promise of more sustainable production routes for towards bulk and fine chemicals. Their broad applicability, reactor concepts, achieved milestones and future perspectives are described herein.

Temperature plays an important role in the formation of point defects. We review different contributions to defect free energies and how to model them, outlining strategies to reduce the associated computational burden.

This tutorial review introduces recent advances in molecular afterglow imaging using organic materials with a focus on afterglow substrates, afterglow mechanisms, design principles of afterglow imaging probes, and their biomedical applications.