Themed collection CC 60th Anniversary Authors Collection

This review provides an electrosynthesis strategy of H₂O₂via the 2e⁻ ORR, covering aspects of reaction mechanisms, performance assessment, catalyst engineering, and setups for scaling up H₂O₂ production.

This highlight article summarizes the recent developments and challenges in photocatalytic production of hydrogen peroxide and looks forward to the development direction of this field.

DNA nanostructures are easy to design and construct, have good biocompatibility, and show great potential in biosensing and drug delivery when combined with CRISPR/Cas systems.

This review introduces tetrazoles as the building blocks. The tetrazole ring offers four nitrogens, thereby assisting in multiple binding sites. The consequence is usually polymeric networks, but meticulous stratagem can form discrete cages as well.

A nickel-catalysed reductive ring-opening reaction of 7-oxabenzonorbornadienes with acyl chlorides as the electrophilic coupling partner was developed, generating β-acyl naphthalene as the unique product without any α iso.

We report the synthesis and properties of a π-extended indeno[2,1-a]fluorene derivative which is an antiaromatic diradicaloid exhibiting small diradical character despite showing a small singlet–triplet energy gap.

Catalytic silylation of aryl/alkenyl electrophiles using silylboronic esters with no base-mediated borylation has been developed.

A stereoselective synthesis of an advanced trans-decalin intermediate towards the total synthesis of anthracimycin is described.

We have developed a novel Ni-catalyzed reductive cross-coupling reaction of aryl bromides and alkyl iodides via a photoactive electron donor–acceptor (EDA) complex.

RE-UiO-66 analogues are synthesized using RE acetates as precursors for the first time.

A simple photocatalytic procedure for the synthesis of (poly)cyclic O,O- and N,O-acetals from various enol ethers, N-acyl enamines or Boc-protected enamines has been developed.

The chemistry and reactivity of a free gem-dithiol, 1,3-diphenylpropane-2,2-dithiol, and its derivatives (S-nitrosothiol and dithiirane) are studied. These compounds can release H₂S, NO, or induce S-persulfidation.

A robust titanium-based metal–organic framework, MFM-300(Ti), exhibits an exceptional NH₃ adsorption of 23.4 mmol g⁻¹ with a record-high packing density of 0.84 g cm⁻³, promoted by strong binding interactions of NH₃ to the framework oxygen sites.

This study proposes a mitochondrial targeting optimization by uncovering the synergistic influence of Nernst potential and partitioning contributions, reshaping our understanding of cellular localization.

Described herein is a Cu-catalyzed diarylation of aromatic alkynes via radical docking-migration pathways, leading to a broad range of valuable triarylethenes.

Glycosyl radicals generated from readily available and bench-stable allyl glycosyl sulfones, promoting radical cascade cyclization for preparing glycosyl benzothiazoles.

A metal-free protocol utilizing DBU catalysis for post-Ugi amide-ester exchange and Conia-ene double cyclization has been successfully developed, allowing the synthesis of diverse highly functionalized benzo-fused spiroindolines with anti-cancer activities under mild conditions.

Triphenyl phosphane (TPP) and an epoxide as a fuel system transiently transformed a non-catalytic six-component turnstile into a four-component catalytic rotor releasing N-methyl pyrrolidine and a copper(I) complex.

This work reports novel gold catalysis and DBU-promoted cyclizations between 2-(2-ethynylaryl)acetonitriles and anthranils to construct benzo[7,8]indolizino[2,3,4,5-ija]quinazoline frameworks.

Polyphenols, notably gallic acid (GA), act as a biphasic modulator of tau liquid–liquid phase separation in a concentration-dependent manner. GA accelerates the sol-to-gel transition and inhibits tau aggregate-associated toxicity.

A new armchair carbon nanobelt is successfully synthesized by tuning the regioselectivity of the Scholl reaction of the quinquephenyl units in the arylated [12]cycloparaphenylene substrate.

Conjugates of proteins and bottlebrush polymers are prepared using an “organometallic swap” strategy.

A bench-top stable borane with an appended redox-active phenothiazine motif can be oxidized by a single-electron oxidant to “unlock” a potent radical cationic Lewis acid catalyst for dimerization and hydrosilylation reactions.

Light triggers substantial changes in the morphology of synthetic membranes composed of stimuli-responsive diazobenzene lipid building blocks.

Electronic modification of SnO₂ using doping to enhance electrocatalytic CO₂ reduction to formate.

Organocatalytic asymmetric desymmetrization of prochiral cyclohexane-1,3-diones has been demonstrated through the merging of iminium and enamine activation.

Water-dispersible fluorescent bolaamphiphiles have been developed. Also, luminescence color change in response to humidity has been demonstrated with a composite material.

A hetero-bimetallic Ru(II)–Ir(III) complex Ru-Ir was developed to act as a type-I and type-II dual photosensitizer for effective cancer photodynamic therapy under hypoxia.

A palladium-catalysed C2–H alkynylation of benzophospholes with alkynyl bromides has been developed to afford the corresponding phosphole-alkyne conjugations in good yields.

We debut phosphorus nitrogen cages as a new family of convenient and tunable 3-dimensional connectors for reticular chemistry (crystalline or amorphous).

A hollow Ag/AgCl nanoelectrode is developed for single-cell drug infusion and chloride detection.

A one-pot sequential process for the challenging ortho/meta C–H difunctionalizations of simple benzamide derivatives: a direct access to polyfunctionalized arenes.

Fluoride-activated ligands drive a rapid sol–gel transition by cross-linking metals to build physical barriers that contain fluids and suppress chemical dissipation.