Biomimetic drug-delivery systems for the management of brain diseases
This review summarizes the biological properties of biomimetic DDSs and their applications in the treatment of CNS diseases.
Virus-derived materials: bury the hatchet with old foes
Viruses, with special architecture and unique biological nature, can be utilized for various biomedical applications.
Biomimetic Cell-derived Nanocarriers for Modulating Immune Responses
Recent progress in supramolecular peptide assemblies as virus mimics for cancer immunotherapy
Supramolecular peptide assemblies can mimic natural viruses and serve as well-defined, dynamic and multifunctional nanoplatforms for cancer immunotherapy, where the peptide segments act as antigens, adjuvants and carriers.
Biomimetic and bioinspired strategies for oral drug delivery
Herein we provide a state-of-the-art review on the current progress of biomimetic particulate oral delivery systems.
A forskolin-conjugated insulin analog targeting endogenous glucose-transporter for glucose-responsive insulin delivery
A new insulin analog has been obtained by modifying insulin with forskolin (designated as insulin-F), a glucose transporter (Glut) inhibitor. Insulin-F is capable of binding to Glut on the plasma membrane in a glucose-dependent manner.
Delivery of siRNA therapeutics using cowpea chlorotic mottle virus-like particles
While highly promising in medicine, gene therapy requires delivery agents to protect and target nucleic acid therapeutics.
Engineering microglia as intraoperative optical imaging agent vehicles potentially for fluorescence-guided surgery in gliomas
Carotid artery injection of DiDBV2-Fe into glioblastoma-bearing mice and rats potentially for fluorescence-guided tumor surgery leads to significant accumulation and retention by the brain tumors.
Tannic acid-based nanogel as an efficient anti-inflammatory agent
Biologically produced reactive oxygen species (ROS) are important signaling molecules in the human body.
Biomimetic drug delivery platforms based on mesenchymal stem cells impregnated with light-responsive submicron sized carriers
Synthetic organic and inorganic carriers often have limitations associated with problematic targeting ability or non-optimized pharmacokinetics, and, therefore, they have restricted therapeutic potential.
Biomimetic proteoglycan nanoparticles for growth factor immobilization and delivery
Growth factor delivery is often challenging due to their short half-life, low stability, and rapid deactivation. Here, we engineered novel biomimetic proteoglycan nanocarriers for the immobilization and controlled release of growth factors.
About this collection
This collection on Biomimetic Therapeutics (BTs) presents the latest advances in biomimetic delivery and therapy, and offer an overview of various cutting-edge theranostics strategies. The collection has been Guest Edited by Professor Yongzhuo Huang (Shanghai Institute of Materia Medica, CAS) and Professor Jianqing Gao (Zhejiang University) and it will include research on topics such as endogenous elements, cell-membrane camouflaged BTs, cell-based BTs, and bacteria or virus-mimicking BTs.