Themed collection Biomaterials Science Recent HOT Articles

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Nanoscale metal–organic frameworks for the intracellular delivery of CRISPR/Cas9 genome editing machinery

The discovery of CRISPR/Cas9 genome-editing technology enables the precise manipulation of mammalian DNA sequences for treating genetic disorders.

Graphical abstract: Nanoscale metal–organic frameworks for the intracellular delivery of CRISPR/Cas9 genome editing machinery
From the themed collection: Biomaterials Science Recent HOT Articles
Minireview

Application and research progress of phase change materials in biomedical field

Application of phase change materials (PCMs) in biomedical field.

Graphical abstract: Application and research progress of phase change materials in biomedical field
From the themed collection: Biomaterials Science Recent HOT Articles
Minireview

In situ self-assembled peptide nanofibers for cancer theranostics

Nanofibers constructed by an in situ self-assembly strategy hold tremendous promise for cancer theranostics with characteristic functions and biological effects in different parts of tumor tissue.

Graphical abstract: In situ self-assembled peptide nanofibers for cancer theranostics
From the themed collection: Biomaterials Science Recent HOT Articles
Minireview

Recent advances in stimuli-responsive in situ self-assembly of small molecule probes for in vivo imaging of enzymatic activity

Stimuli-responsive in situ self-assembly of small molecule probes into nanostructures has been promising for the construction of molecular probes for in vivo imaging.

Graphical abstract: Recent advances in stimuli-responsive in situ self-assembly of small molecule probes for in vivo imaging of enzymatic activity
From the themed collection: Biomaterials Science Recent HOT Articles
Review Article

Recent developments in mussel-inspired materials for biomedical applications

Over the decades, researchers have strived to synthesize and modify nature-inspired biomaterials, with the primary aim to address the challenges of designing functional biomaterials for regenerative medicine and tissue engineering.

Graphical abstract: Recent developments in mussel-inspired materials for biomedical applications
From the themed collection: Biomaterials Science Recent HOT Articles
Review Article

Deoxyribonucleic acid anchored on cell membranes for biomedical application

This review provides an overview of engineering cellular membranes with deoxyribonucleic acids to manipulate cellular behaviors and functionalities for biomedical applications. The current challenges and future directions are summarized and proposed.

Graphical abstract: Deoxyribonucleic acid anchored on cell membranes for biomedical application
From the themed collection: Biomaterials Science Recent HOT Articles
Review Article

Marine origin materials on biomaterials and advanced therapies to cartilage tissue engineering and regenerative medicine

This comprehensive review brings a larger perspective on the most recent developments in new tissue-scaffolds based on marine origin polymers envisaging the treatment and repair of human articular cartilage tissues.

Graphical abstract: Marine origin materials on biomaterials and advanced therapies to cartilage tissue engineering and regenerative medicine
From the themed collection: Biomaterials Science Recent HOT Articles
Open Access Review Article

Recent progress in nanotechnology-based drug carriers for celastrol delivery

Various types of celastrol nanoformulations have been developed to treat a number of disorders, including cancer, inflammatory, auto-immune, obesity.

Graphical abstract: Recent progress in nanotechnology-based drug carriers for celastrol delivery
From the themed collection: Biomaterials Science Recent HOT Articles
Review Article

Recent advances in covalent organic frameworks for cancer diagnosis and therapy

Emerging opportunities and challenges of covalent organic frameworks (COFs) in cancer diagnosis and therapy are summarized. The future research directions of COF-based nanoplatforms for cancer theranostics are presented.

Graphical abstract: Recent advances in covalent organic frameworks for cancer diagnosis and therapy
From the themed collection: Biomaterials Science Recent HOT Articles
Review Article

Fascinating MXene nanomaterials: emerging opportunities in the biomedical field

In recent years, there has been rapid progress in MXene research due to its distinctive two-dimensional structure and outstanding properties.

Graphical abstract: Fascinating MXene nanomaterials: emerging opportunities in the biomedical field
From the themed collection: Biomaterials Science Recent HOT Articles
Review Article

Molecular engineering of antimicrobial peptide (AMP)–polymer conjugates

Engineering the architectures of antimicrobial peptide-polymer conjugates provides compelling opportunities to balance bactericidal activity with stability and biocompatibility, to address the critical need for innovative antimicrobial treatments.

Graphical abstract: Molecular engineering of antimicrobial peptide (AMP)–polymer conjugates
From the themed collection: Biomaterials Science Recent HOT Articles
Review Article

Necessity of regulatory guidelines for the development of amyloid based biomaterials

The recent surge in amyloid-based biomaterial development needs regulatory guidelines and safety assessment to avoid adverse health effects.

Graphical abstract: Necessity of regulatory guidelines for the development of amyloid based biomaterials
From the themed collection: Biomaterials Science Recent HOT Articles
Review Article

Peptide-based supramolecular hydrogels for bioimaging applications

Peptide-based supramolecular hydrogels have unique merits in bioimaging applications.

Graphical abstract: Peptide-based supramolecular hydrogels for bioimaging applications
From the themed collection: Biomaterials Science Recent HOT Articles
Review Article

Recent advances in semiconducting polymer dots as optical probes for biosensing

This review mainly summarized the recent results that used bright polymer dots (Pdots) for the detection of different analytes such as reactive oxygen species (ROS), metal ions, pH values, and a variety of biomolecules.

Graphical abstract: Recent advances in semiconducting polymer dots as optical probes for biosensing
From the themed collection: Biomaterials Science Recent HOT Articles
Review Article

The development of phosphorescent probes for in vitro and in vivo bioimaging

This review mainly introduces the phosphorescent probes applied in vitro and in vivo bioimaging.

Graphical abstract: The development of phosphorescent probes for in vitro and in vivo bioimaging
From the themed collection: Biomaterials Science Recent HOT Articles
Review Article

Photothermal bactericidal surfaces: killing bacteria using light instead of biocides

Recent developments of photothermal bactericidal surfaces based on immobilized photothermal agents to kill bacteria through hyperthermia effects are reviewed.

Graphical abstract: Photothermal bactericidal surfaces: killing bacteria using light instead of biocides
From the themed collection: Biomaterials Science Recent HOT Articles
Open Access Review Article

Biomaterials-based approaches to model embryogenesis

Biomaterials are emerging as invaluable tools to investigate key mechanisms of human development using advance in vitro models. Nanomaterials can contribute to further refine these models.

Graphical abstract: Biomaterials-based approaches to model embryogenesis
From the themed collection: Biomaterials Science Recent HOT Articles
Review Article

Single-atom nanozymes for biological applications

Single-atom nanozymes with high catalytic activity, selectivity, and stability have been used in the treatment of cancer, wound trauma, and brain diseases.

Graphical abstract: Single-atom nanozymes for biological applications
From the themed collection: Biomaterials Science Recent HOT Articles
Review Article

Structured micro/nano materials synthesized via electrospray: a review

Electrospray enables the preparation of versatile spherical, non-spherical, and assembled micro/nano materials.

Graphical abstract: Structured micro/nano materials synthesized via electrospray: a review
From the themed collection: Biomaterials Science Recent HOT Articles
Open Access Review Article

A call for action to the biomaterial community to tackle antimicrobial resistance

The global surge of antimicrobial resistance (AMR) is a major concern for public health and proving to be a key challenge in modern disease treatment, requiring action plans at all levels.

Graphical abstract: A call for action to the biomaterial community to tackle antimicrobial resistance
From the themed collection: Biomaterials Science Recent HOT Articles
Review Article

Polydopamine free radical scavengers

This feature article summarizes the recent progress, challenges and future directions of free radical scavengers based on polydopamine, including the integrated mechanism, current regulating strategies, and kinds of biomedical applications.

Graphical abstract: Polydopamine free radical scavengers
From the themed collection: Biomaterials Science Recent HOT Articles
Review Article

Hemostatic nanotechnologies for external and internal hemorrhage management

Hemostatic nanotechnologies promote the development of various hemostatic materials for external and internal hemorrhage management.

Graphical abstract: Hemostatic nanotechnologies for external and internal hemorrhage management
From the themed collection: Biomaterials Science Recent HOT Articles
Review Article

Recent advances in improving tumor-targeted delivery of imaging nanoprobes

This review discusses various recent strategies based on different targeting ligands to improve the tumor-specific targeting of nanoprobes toward precision imaging diagnosis.

Graphical abstract: Recent advances in improving tumor-targeted delivery of imaging nanoprobes
From the themed collection: Biomaterials Science Recent HOT Articles
Communication

Facile synthesis of dendrimer like mesoporous silica nanoparticles to enhance targeted delivery of interleukin-22

Interleukin (IL)-22 is a multifunctional cytokine with a very short half-life that activates STAT3 and can elicit an anti-inflammatory response. We show encapsulation of IL-22 in LPMSN enhances its biological activity and stability in in vitro and human colonic organoids.

Graphical abstract: Facile synthesis of dendrimer like mesoporous silica nanoparticles to enhance targeted delivery of interleukin-22
From the themed collection: Biomaterials Science Recent HOT Articles
Communication

Non-contact measurement of internal body temperature using subcutaneously implanted diamond microparticles

We demonstrate the feasibility of subcutaneously implanted fluorescent diamond microparticles as a temperature probe for the non-contact measurement of internal body temperature using a homemade wide-field optically detected magnetic resonance imager.

Graphical abstract: Non-contact measurement of internal body temperature using subcutaneously implanted diamond microparticles
From the themed collection: Biomaterials Science Recent HOT Articles
Communication

3D printing of lubricative stiff supramolecular polymer hydrogels for meniscus replacement

Thickening a concentrated solution of a multiple-H-bonding monomer (MHM) and a zwitterion monomer (ZM) with a soft poly(MHM-co-ZM) gel enables direct printing of the MHM, and post-polymerization generates a stiff and lubricative hydrogel meniscus.

Graphical abstract: 3D printing of lubricative stiff supramolecular polymer hydrogels for meniscus replacement
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Isolation and characterization of porcine macrophages and their inflammatory and fusion responses in different stiffness environments

Evaluating the host immune response to biomaterials is an essential step in the development of medical devices and tissue engineering strategies.

Graphical abstract: Isolation and characterization of porcine macrophages and their inflammatory and fusion responses in different stiffness environments
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

A tripartite carbohydrate-binding module to functionalize cellulose nanocrystals

mSA-CBM3-AzF is a chimeric protein targeting cellulose nanocrystals (CNCs) with high affinity. It presents two additional domains providing a wide choice of chemical and biological molecules to functionalize CNCs.

Graphical abstract: A tripartite carbohydrate-binding module to functionalize cellulose nanocrystals
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Improved epithelial cell–cell adhesion using molecular mobility of supramolecular surfaces

The role of molecular mobility on polyrotaxane surfaces was investigated in epithelial cell–cell adhesion. The polyrotaxane surfaces with higher mobility induced cytoplasmic YAP localization, leading to stronger cell–cell adhesion.

Graphical abstract: Improved epithelial cell–cell adhesion using molecular mobility of supramolecular surfaces
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

The in vivo fate of tobacco mosaic virus nanoparticle theranostic agents modified by the addition of a polydopamine coat

The coating of tobacco mosaic virus (TMV) nanoparticles Gd-Cy5-TMV with polydopamine (PDA) increased protein corona formation and shortened plasma circulation, but minimized recognition by anti-TMV antibodies, and extended organ distribution/clearance.

Graphical abstract: The in vivo fate of tobacco mosaic virus nanoparticle theranostic agents modified by the addition of a polydopamine coat
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

A multifunctional green antibacterial rapid hemostasis composite wound dressing for wound healing

A green multifunctional wound dressing with low-cost that can accelerate wound healing in comparison to gauze.

Graphical abstract: A multifunctional green antibacterial rapid hemostasis composite wound dressing for wound healing
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Dual-sensitive dual-prodrug nanoparticles with light-controlled endo/lysosomal escape for synergistic photoactivated chemotherapy

The dual-sensitive dual-prodrug nanoparticles (DDNPs) with light-controlled drug-release on demand and endo/lysosomal escape for synergistic photoactivated chemotherapy.

Graphical abstract: Dual-sensitive dual-prodrug nanoparticles with light-controlled endo/lysosomal escape for synergistic photoactivated chemotherapy
From the themed collection: Biomaterials Science Recent HOT Articles
Open Access Paper

Interrogating cardiac muscle cell mechanobiology on stiffness gradient hydrogels

Mechanobiology of H9C2 cells and neonatal cardiomyocytes mapped using stiffness gradient hydrogels with a range of extracellular matrix coatings, revealing stiffness-driven trends in cell morphology, YAP and MRTF-A expression.

Graphical abstract: Interrogating cardiac muscle cell mechanobiology on stiffness gradient hydrogels
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

A facile method for high-throughput screening of drug-eluting coatings in droplet microarrays based on ultrasonic spray deposition

Droplet microarrays are fabricated for the high-throughput screening of drug-eluting coatings via ultrasonic spray deposition technique.

Graphical abstract: A facile method for high-throughput screening of drug-eluting coatings in droplet microarrays based on ultrasonic spray deposition
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Microneedle-mediated delivery of MIL-100(Fe) as a tumor microenvironment-responsive biodegradable nanoplatform for O2-evolving chemophototherapy

MIL-100(Fe) nanoparticles integrated microneedles were employed to codeliver the hydrophobic photosensitizer zinc phthalocyanine (ZnPc) and the chemotherapeutical drug doxorubicin hydrochlorate (Dox) (Z/D@MOF) for O2-evolving chemophototherapy.

Graphical abstract: Microneedle-mediated delivery of MIL-100(Fe) as a tumor microenvironment-responsive biodegradable nanoplatform for O2-evolving chemophototherapy
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

c-Met-targeted near-infrared fluorescent probe for real-time depiction and dissection of perineural invasion and lymph node metastasis lesions in pancreatic ductal adenocarcinoma xenograft models

c-Met-targeted near-infrared fluorescent probe has excellent targeting ability to pancreatic ductal adenocarcinoma (PDAC), and can be used for real-time detection of lymph node metastasis and perineural invasion lesions in PDAC xenograft models.

Graphical abstract: c-Met-targeted near-infrared fluorescent probe for real-time depiction and dissection of perineural invasion and lymph node metastasis lesions in pancreatic ductal adenocarcinoma xenograft models
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Pre-shear bioprinting of highly oriented porous hydrogel microfibers to construct anisotropic tissues

A pre-shear bioprinting strategy of oriented porous cell-laden hydrogel microfiber to construct anisotropic tissues is first proposed. Different cells encapsulated in the oriented microfibers exhibit oriented growth behaviors similar to that in vivo.

Graphical abstract: Pre-shear bioprinting of highly oriented porous hydrogel microfibers to construct anisotropic tissues
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Hydrophilic hindering and hydrophobic growing: a vesicle glycometabolism multi-drug combination therapeutic against Alzheimer's disease

Advanced drug vehicle exploitation and the sophisticated synergy mechanism revelation are two great difficulties in combination therapy.

Graphical abstract: Hydrophilic hindering and hydrophobic growing: a vesicle glycometabolism multi-drug combination therapeutic against Alzheimer's disease
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

A sulfonate-based polypeptide toward infection-resistant coatings

We developed a mono-component and sulfonate-based polypeptide coating with reversible on-demand bactericidal and antifouling properties.

Graphical abstract: A sulfonate-based polypeptide toward infection-resistant coatings
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

High-stability NIR-II fluorescence polymer synthesized by atom transfer radical polymerization for application in high-resolution NIR-II imaging

This article reports a high-stability NIR-II fluorescence polymer synthesized by atom transfer radical polymerization for application in high-resolution NIR-II imaging.

Graphical abstract: High-stability NIR-II fluorescence polymer synthesized by atom transfer radical polymerization for application in high-resolution NIR-II imaging
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Enhanced anti-tumor efficacy by inhibiting HIF-1α to reprogram TAMs via core-satellite upconverting nanoparticles with curcumin mediated photodynamic therapy

Cur–CSNPs mediated PDT suppress TNBC through the synergistic immunotherapeutic effects by suppressing the expression of HIF-1α to reprogram the pro-tumor TAM2 into the anti-tumor TAM1.

Graphical abstract: Enhanced anti-tumor efficacy by inhibiting HIF-1α to reprogram TAMs via core-satellite upconverting nanoparticles with curcumin mediated photodynamic therapy
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Plasmonic enhanced enzyme activity by catalytic cascade induced mutual benefit tumor starvation/immune/photothermal therapy

Single tumor starvation therapy can activate other signaling pathways in tumor cells and easily induce tumor cell metastasis.

Graphical abstract: Plasmonic enhanced enzyme activity by catalytic cascade induced mutual benefit tumor starvation/immune/photothermal therapy
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Dual-sonosensitizer loaded phase-transition nanoparticles with tumor-targeting for synergistically enhanced sonodynamic therapy

Sonodynamic therapy (SDT) is a fast-growing therapy activated by using ultrasound to initiate a catalytic reaction of sensitizing agents and kill tumor cells through producing reactive oxygen species (ROS).

Graphical abstract: Dual-sonosensitizer loaded phase-transition nanoparticles with tumor-targeting for synergistically enhanced sonodynamic therapy
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Black phosphorus assisted polyionic micelles with efficient PTX loading for remotely controlled release and synergistic treatment of drug-resistant tumors

An illustration of black phosphorus (BP) assisted polyionic mPEG-PDMATC micelles with efficient PTX loading for remotely controlled release and synergistic treatment of drug-resistant tumors.

Graphical abstract: Black phosphorus assisted polyionic micelles with efficient PTX loading for remotely controlled release and synergistic treatment of drug-resistant tumors
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Vitamin E-facilitated carbon monoxide pro-drug nanomedicine for efficient light-responsive combination cancer therapy

A reliable approach is developed to formulate a targeted lipid-coated nanomedicine based on UCNP and co-loaded with CO-prodrug and vitamin E, which can convert NIR light to UV photon to release CO for synergistical cancer therapy with vitamin E.

Graphical abstract: Vitamin E-facilitated carbon monoxide pro-drug nanomedicine for efficient light-responsive combination cancer therapy
From the themed collection: Biomaterials Science Recent HOT Articles
Open Access Paper

Triple-target stimuli-responsive anti-COVID-19 face mask with physiological virus-inactivating agents

The SARS-CoV-2 infection is transmitted by respiratory droplets. We have introduced a new concept of masks, which comprises a threefold mode-of-action: trapping of the virus particles, blocking of the viruses, and finally killing of the viruses.

Graphical abstract: Triple-target stimuli-responsive anti-COVID-19 face mask with physiological virus-inactivating agents
Paper

A pH-triggered fluorescence-switchable extracellular vesicle for tracing drug release and improving drug delivery

A pH-triggered fluorescence-switchable extracellular vesicle is developed by loading zwitterionic fluorescent carbon dots into macrophage cell-secreted vesicles, which enables to improve drug delivery and monitor drug release in real time.

Graphical abstract: A pH-triggered fluorescence-switchable extracellular vesicle for tracing drug release and improving drug delivery
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Synthesis of a zwitterionic N-Ser–Ser-C dimethacrylate cross-linker and evaluation in polyampholyte hydrogels

Polyampholyte hydrogels are attractive materials for tissue engineering scaffolds as they offer a wide variety of features including nonfouling, selective protein delivery, and tunable physical characteristics.

Graphical abstract: Synthesis of a zwitterionic N-Ser–Ser-C dimethacrylate cross-linker and evaluation in polyampholyte hydrogels
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

FeSe2 nanosheets as a bifunctional platform for synergistic tumor therapy reinforced by NIR-II light

FeSe2 nanosheets, relying on their inherent NIR-II-mediated photothermal property and photothermal-enhanced photodynamic performance, provide a new paradigm for the design of advanced drug carriers.

Graphical abstract: FeSe2 nanosheets as a bifunctional platform for synergistic tumor therapy reinforced by NIR-II light
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Asiaticoside-laden silk nanofiber hydrogels to regulate inflammation and angiogenesis for scarless skin regeneration

Asiaticoside-laden silk nanofiber hydrogels regulated inflammation and angiogenesis dynamically in the inflammation and remodeling states, achieving scarless skin regeneration.

Graphical abstract: Asiaticoside-laden silk nanofiber hydrogels to regulate inflammation and angiogenesis for scarless skin regeneration
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Biological sealing and integration of a fibrinogen-modified titanium alloy with soft and hard tissues in a rat model

A Ti–6Al–4V alloy was modified with fibrinogen as mediated by polydopamine, and the skin-implant interface was examined after transcutaneous implantation. The surface modification could inhibit epithelial downgrowth and promote bone regeneration.

Graphical abstract: Biological sealing and integration of a fibrinogen-modified titanium alloy with soft and hard tissues in a rat model
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

A light and hypoxia-activated nanodrug for cascade photodynamic-chemo cancer therapy

A pH-sensitive polymeric nanovesicle is prepared to co-encapsulate Ce6 and tirapazamine (TPZ) as a light and hypoxia-activated nanodrug for highly efficient photodynamic-chemo cancer therapy.

Graphical abstract: A light and hypoxia-activated nanodrug for cascade photodynamic-chemo cancer therapy
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Cascade targeting tumor mitochondria with CuS nanoparticles for enhanced photothermal therapy in the second near-infrared window

A cascade targeting design enables CuS nanoparticles to specifically target tumor mitochondria, achieving significantly improved efficacy of NIR-II photothermal therapy.

Graphical abstract: Cascade targeting tumor mitochondria with CuS nanoparticles for enhanced photothermal therapy in the second near-infrared window
From the themed collection: Biomaterials Science Recent HOT Articles
Open Access Paper

Enhanced NO-induced angiogenesis via NO/H2S co-delivery from self-assembled nanoparticles

The simultaneous delivery of NO and H2S from prepared self-assembled polymeric nanoparticles shows advantages of a controlled release concentration and improved angiogenic properties in vitro and ex vivo by a synergistic effect.

Graphical abstract: Enhanced NO-induced angiogenesis via NO/H2S co-delivery from self-assembled nanoparticles
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

A flexible microfluidic strategy to generate grooved microfibers for guiding cell alignment

A flexible microfluidic strategy to generate grooved microfibers relies on in situ gelling of different concentrations of alginate as anisotropic scaffolds for guiding cell alignment.

Graphical abstract: A flexible microfluidic strategy to generate grooved microfibers for guiding cell alignment
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

A new near-infrared phosphorescent iridium(III) complex conjugated to a xanthene dye for mitochondria-targeted photodynamic therapy

A novel near-infrared phosphorescent iridium(III) complex was developed for cell mitochondria-targeted imaging and photodynamic therapy in vivo.

Graphical abstract: A new near-infrared phosphorescent iridium(iii) complex conjugated to a xanthene dye for mitochondria-targeted photodynamic therapy
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Cytosolic protein delivery via metabolic glycoengineering and bioorthogonal click reactions

Carrier-free cytosolic protein delivery was achieved via metabolic glycoengineering and bioorthogonal click reactions.

Graphical abstract: Cytosolic protein delivery via metabolic glycoengineering and bioorthogonal click reactions
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Oxygen-carrying nanoparticle-based chemo-sonodynamic therapy for tumor suppression and autoimmunity activation

DTX/CS–Rh–PFC nanoparticles are hydrolyzed by glutathione in tumor cells, releasing DTX and oxygen molecules, and thus exhibit good anti-tumor ability.

Graphical abstract: Oxygen-carrying nanoparticle-based chemo-sonodynamic therapy for tumor suppression and autoimmunity activation
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

The effects of VEGF-centered biomimetic delivery of growth factors on bone regeneration

The Biomimetic group was prepared by combining MP particles, LSS particles, and pluornic mixture-infiltrated LSS particles. The Biomimetic group resulted in faster bone regeneration than the Continuous group, unlike the in vitro observations.

Graphical abstract: The effects of VEGF-centered biomimetic delivery of growth factors on bone regeneration
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Dual effect of molecular mobility and functional groups of polyrotaxane surfaces on the fate of mesenchymal stem cells

Mesenchymal stem cells on polyrotaxane surfaces underwent enhanced osteoblast and adipocyte differentiation. Two independent parameters, high molecular mobility and negative charge on the surfaces, may not offset the effect to promote both differentiation.

Graphical abstract: Dual effect of molecular mobility and functional groups of polyrotaxane surfaces on the fate of mesenchymal stem cells
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Sulfoxide-functionalized nanogels inspired by the skin penetration properties of DMSO

Sulfoxide-functionalized nanogels show a high potential to effectively emulate the skin penetration enhancing properties of DMSO without its negative side effects.

Graphical abstract: Sulfoxide-functionalized nanogels inspired by the skin penetration properties of DMSO
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Near-infrared light-triggered nanobomb for in situ on-demand maximization of photothermal/photodynamic efficacy for cancer therapy

A novel near-infrared light-responsive nanobomb was developed to overcome the aggregation issues of PTT/PDT agents and fundamentally improve the synergistic efficacy in cancer therapy.

Graphical abstract: Near-infrared light-triggered nanobomb for in situ on-demand maximization of photothermal/photodynamic efficacy for cancer therapy
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Theranostic supramolecular polymers formed by the self-assembly of a metal-chelating prodrug

The direct linkage of two camptothecin moieties to a metal chelator creates a self-assembling prodrug capable of associating in aqueous solution into theranostic supramolecular polymers.

Graphical abstract: Theranostic supramolecular polymers formed by the self-assembly of a metal-chelating prodrug
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Novel anilino quinazoline-based EGFR tyrosine kinase inhibitors for treatment of non-small cell lung cancer

The two novel anilino quinazoline-based EGFR-TKIs have promising anti-tumor activity and limited hepatotoxicity, representing excellent candidates for combating the NSCLC.

Graphical abstract: Novel anilino quinazoline-based EGFR tyrosine kinase inhibitors for treatment of non-small cell lung cancer
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Green facile synthesis to develop nanoscale coordination polymers as lysosome-targetable luminescent bioprobes

A facile green hand grinding technique has been adopted towards the design of three nanoscale crystalline materials that serves as an excellent selective bio tracker for intracellular lysosome.

Graphical abstract: Green facile synthesis to develop nanoscale coordination polymers as lysosome-targetable luminescent bioprobes
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

An alpha/beta chimeric peptide molecular brush for eradicating MRSA biofilms and persister cells to mitigate antimicrobial resistance

An α/β chimeric polypeptide molecular brush shows excellent performance in eradicating established biofilms, persister cells, and clinically isolated multi-drug resistant Gram-positive bacteria.

Graphical abstract: An alpha/beta chimeric peptide molecular brush for eradicating MRSA biofilms and persister cells to mitigate antimicrobial resistance
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Cascaded bio-responsive delivery of eNOS gene and ZNF580 gene to collaboratively treat hindlimb ischemia via pro-angiogenesis and anti-inflammation

The cascaded, bio-responsively delivered eNOS gene and ZNF580 gene overcome transfection bottlenecks and collaboratively exert anti-ischemic function via promoting angiogenesis and alleviating inflammation.

Graphical abstract: Cascaded bio-responsive delivery of eNOS gene and ZNF580 gene to collaboratively treat hindlimb ischemia via pro-angiogenesis and anti-inflammation
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Fe-TCPP@CS nanoparticles as photodynamic and photothermal agents for efficient antimicrobial therapy

Photodynamic and photothermal agents for efficient antimicrobial therapy.

Graphical abstract: Fe-TCPP@CS nanoparticles as photodynamic and photothermal agents for efficient antimicrobial therapy
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Increased cross-linking micelle retention in the brain of Alzheimer's disease mice by elevated asparagine endopeptidase protease responsive aggregation

The asparagine endopeptidase responsive cross-linking micelle (RCM) increased the brain retention of Alzheimer's disease mice.

Graphical abstract: Increased cross-linking micelle retention in the brain of Alzheimer's disease mice by elevated asparagine endopeptidase protease responsive aggregation
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Ultra-small platinum nanoparticles on gold nanorods induced intracellular ROS fluctuation to drive megakaryocytic differentiation of leukemia cells

Au@Pt nanoparticles induce chronic myeloid leukemia cells to differentiate into megakaryocytes by causing intracellular ROS fluctuations with multiple enzyme-like activities.

Graphical abstract: Ultra-small platinum nanoparticles on gold nanorods induced intracellular ROS fluctuation to drive megakaryocytic differentiation of leukemia cells
From the themed collection: Biomaterials Science Recent HOT Articles
90 items - Showing page 1 of 2

About this collection

Welcome to our online rolling collection of the hottest work published in Biomaterials Science. Here we feature recent Biomaterials Science articles highlighted as HOT by the handling editor or our referees.

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