An overview of electrochemical biosensors used for COVID-19 detection
This short review presents the latest advances in the field of electrochemical biosensors, focusing particularly on impedimetric biosensors for the direct measurement of analytes.
Minireview
Response strategies and biological applications of organic fluorescent thermometry: cell- and mitochondrion-level detection
In this review, we primarily summarized four temperature-response strategies. Then, we further analyzed the chemical modifications and biological applications of the probes. Finally, we have provided a prospective on the future development of probes.
Sandwich-type aptamer-based biosensors for thrombin detection
Aptasensors for thrombin, which feature a sandwich-type configuration, hold great promise in terms of their potential applications in diagnostics and therapeutics.
Advances in MXene-based luminescence sensing strategies
MXene-based luminescence sensing strategies include fluorescence, electrochemiluminescence and chemiluminescence sensors. Their performance are summarized, and their challenges and application perspectives are discussed.
Surface charge-induced electrospray for high-throughput analysis of complex samples and electrochemical reaction intermediates using mass spectrometry
A novel surface charge induced electrospray ionization is proposed due to its features of no contact between sample solution and metal electrode, fast analytical process (less than 40 s), and high analytical sensitivity.
In situ setup for screening of drug permeation by NMR spectroscopy
A diffusion cell setup within an NMR tube enables automated drug permeability measurements. Challenges, modifications, and additional applications are discussed.
Benzorhodol derived far-red/near-infrared fluorescent probes for selective and sensitive detection of butyrylcholinesterase activity in living cells and non-alcoholic fatty liver of zebrafish
Strong cation-exchange combined with mass spectrometry reveals the glycoform heterogeneity of sialylated glycoproteins
Strong cation exchange – mass spectrometry method was optimized for intact analysis of sialylation glycoproteins.
A label-free photoelectrochemical biosensor for silver ions based on Zn–Co doped C and CdS QD nanomaterials
A photoelectrochemical (PEC) biosensor for silver ion (Ag+) detection was constructed based on Zn–Co doped C and CdS quantum dot (CdS QD) nanomaterials.
Investigating the mechanistic impact of pork soft tissue preparation techniques on the classification precision of laser-induced breakdown spectroscopy
The mechanism of the effect of sample preparation methods on the signal was explored through an in-depth study of the plasma density and temperature.
A Mitochondria-specific NIR Fluorescence Probe for Dual-detection of Sulfur Dioxide and Viscosity in Living Cells and Mice
A paper-based point-of-care device for the detection of cysteine using gold nanoparticles from whole blood
The colorimetric detection of cysteine (Cys) from whole blood using a dried PVP–AuNP paper surface as a colorimetric probe.
Paper
Screening of α-amylase/trypsin inhibitor activity in wheat, spelt and einkorn by high-performance thin-layer chromatography
The potential of HPTLC was studied to analyse the inhibitory properties of ATIs from wheat, spelt, and einkorn flours. It provided information on changes in individual saccharides or peptides and was more reliable than conventional in-vial assays.
Temperature-sensitive metal-enhanced fluorescence and plasmon resonance energy transfer
Experimental decoupling of the effects of plasmon resonance energy transfer (PRET) and metal-enhanced fluorescence (MEF) within the same nanometal–fluorophore pair is fascinating but challenging.
A highly selective probe engineered to detect polarity and distinguish normal cells and tumor cells in tissue sections
We have designed a polarity fluorescent probe (DCI-Cou-polar) with high selectivity for diagnosing cancer.
Layer-by-layer assembly of homopolypeptide polyelectrolytes on asymmetric nanochannels for the detection of nickel ions
We report PA-γ-PGA-modified asymmetric nanochannels that enable ultra-sensitive detection of Ni2+ (limit of detection is 1 × 10−8 M).
Simple and convenient preconcentration procedure for the isotopic analysis of uranium in seawater
Amidoxime adsorbent was synthesised by graft polymerisation. The adsorbent was efficient for collection of U in seawater for both the adsorption and desorption steps, thus affording a new strategy for measurement of U isotopes.
Analysis of O-acetylated sialic acids by 3-nitrophenylhydrazine derivatization combined with LC-MS/MS
The 3-NPH-labeled sialic acids produce a high abundance of reporter ions, which can improve the accuracy of quantitative analysis of O-acetylated species.
A lateral flow strip for on-site detection of homocysteine based on a truncated aptamer
A lateral flow strip based on a truncated aptamer for on-site detection of homocysteine in human serum.
A chemiluminescence immunoassay for type IV collagen as a promising marker for liver fibrosis and cirrhosis
Herein, a magnetic bead-based chemiluminescence assay is reported to detect type IV collagen (col-IV) in serum samples.
A pH-response-based fluorescent probe for detecting the mitophagy process by tracing changes in colocalization coefficients
A novel pH-response fluorescent probe MP for the detection of mitophagy process via tracing colocalization coeffcients was developed.
An electrochemiluminescence microsensor based on DNA-silver nanoclusters amplification for detecting cellular adenosine triphosphate
An ECL microsensor integrating RCA magnification and in situ DNA-templated AgNC generation for sensitive detection of cellular ATP.
Sensitive detection of herbicide residues using field-amplified sample injection coupled with electrokinetic supercharging in flow-gated capillary electrophoresis
A low-conductivity sample buffer plug was electroosmotically injected, and then the FASI-EKS was conducted at a reversed voltage polarity. When the conentrated analyte region arrived at the capillary inlet edge, a normal voltage was applied for separations.
Mineral oil emulsion species and concentration prediction using multi-output neural network based on fluorescence spectra in the solar-blind UV band
The accurate monitoring of oil spills is crucial for effective oil spill recovery, volume determination, and cleanup.
A ratiometric fluorescent probe with a large Stokes shift for the detection of Hg2+ and its applications in environmental sample and living system analysis
A coumarin-based ratiometric fluorescent probe CMT was synthesized for the detection of Hg2+ and applied to environmental analysis and bioimaging.
Novel nickel(II) phthalocyanine/reduced graphene oxide: an electrochemical sensing platform for analysis of hydroquinone and chloramphenicol in environmental samples
The novel nickel(II) phthalocyanine (NiTBPBXCAPc) and rGO were confirmed by spectroscopic and microscopic method. The NiTBPBXCAPc@rGO nanocomposite has been developed for sensitive and selective detection of hydroquinone and chloramphenicol.
Self-aspiration sampling design for rapid analyses of volatile organic compounds based on atmospheric pressure chemical ionization/photoionization combined ionization source mass spectrometry
An atmospheric pressure chemical ionization/photoionization combined ionization source was built through the Venturi effect for introducing samples to detect volatile organic compounds.
Determination of trace morphine and its metabolites in mouse urine using a TpBD functionalized bivalve magnetic nano-adsorbent
In this study, a new type of covalent organic framework (TpBD) functionalized bivalved magnetic microsphere (TpBD-DS MNS) adsorbent was applied for the enrichment and detection of trace morphine and its metabolites in mouse urine.
Heterologous antigen selection of chicken single-chain variable fragments against thiamethoxam
Single-chain variable fragments (scFvs) are valuable in the development of immunoassays for pesticide detection.
A novel and sensitive electrochemical aptasensor for sulfadimethoxine detection based on the triple helix/exonuclease I-assisted double-amplification strategy
The triple helix/Exo I-assisted double-amplification strategy effectively improves the sensitivity of the aptasensor. The aptasensor has simple operation and strong specificity and has been applied to detect sulfadimethoxine (SDM) in real samples.
Development and validation of a GC Orbitrap-MS method for the analysis of phthalate esters (PAE) and bis(2-ethylhexyl)adipate (DEHA) in atmospheric particles and its application for screening PM2.5 from Curitiba, Brazil
GC Orbitrap-MS method for the analysis of phthalate esters (PAE) and bis(2-ethylhexyl)adipate (DEHA) in atmospheric particles has been developed and applied for screening PM2.5 from Curitiba, Brazil.
A novel electrochemical sensor based on a molecularly imprinted polymer for highly selective and sensitive determination of rutin from herbal supplements and plant extracts
Rutin (RUT), a natural flavonoid with various beneficial pharmacological actions such as cardioprotective, antioxidant, anti-inflammatory, neuroprotective, etc., is found in the content of many plants that are consumed daily.
A hybrid variable selection method combining Fisher's linear discriminant combined population analysis and an improved binary cuckoo search algorithm
In this paper, a novel hybrid variable selection method for model building by near-infrared (NIR) spectroscopy is proposed for composition measurement in industrial processes.
Green direct ultrasonic slurry sampling and electrothermal atomic absorption spectrometry method for metal analysis of solid plastics samples
This work presents a “green” analytical method developed for the determination of potentially toxic metals such as, Ba and Cr in solid plastics samples by SS-ETAAS method.
A Tröger's base-linked aluminium phthalocyanine polymer for discriminative electrochemical sensing of the antibiotic isoniazid
A novel sensing platform based on a Tröger's base-linked aluminium phthalocyanine polymer was proposed for specific, rapid and low-cost detection of the antibiotic isoniazid in pharmaceutical and biological fluids.
Naked-eye detection of plant viral disease using polymerase chain reaction amplification and DNAzyme
A convenient and highly sensitive biosensor for the naked-eye detection of plant viral disease is proposed by using the PCR-induced generation of DNAzyme.
A novel nanoprobe for visually investigating the controversial role of miRNA-34a as an oncogene or tumor suppressor in cancer cells
Identify the controversial role of miRNA-34a as an oncogene or tumor suppressor. Simultaneous fluorescence imaging of miRNA-34a and caspase-3 in living cells.
A highly sensitive fluorescence probe for on-site detection of nerve agent mimic diethylchlorophosphonate DCP
A unique fluorescent probe has been developed for the detection of diethyl dichloropropylphosphonate (DCP). A portable test strip was prepared and a smartphone sensing platform was proposed to achieve non-contact visual monitoring of DCP concentration.
About this collection
This themed collection features articles published in Analytical Methods marked as HOT by the handling editor or as recommended by referees. Congratulations to all the authors whose articles are featured.