Ultrasensitive electrochemical detection of miRNA based on DNA strand displacement polymerization and Ca2+-dependent DNAzyme cleavage
An ultrasensitive electrochemical sensing strategy for the detection of miRNA is developed combining strand displacement polymerization and a DNAzyme-catalyzed cleavage reaction.
A thumb-size electrochemical system for portable sensors
A thumb-size and precise electrochemical system is designed for sensors in size and cost sensitive applications.
Filter paper based SERS substrate for the direct detection of analytes in complex matrices
Spray coating paper with plasmonic aggregates/hydroxyethylcellulose solution allows fabrication of cheap SERS active substrates for direct analysis of protein/mud samples.
Affinity-free enrichment and mass spectrometry analysis of the ovarian cancer biomarker CA125 (MUC16) from patient-derived ascites
Developing a mass spectrometry-based assay for the ovarian cancer biomarker CA125 (MUC16) is a desirable goal, because it may enable detection of proteoforms that are analytically silent in the current immunoassay.
Sensitive mass spectrometric analysis of carbonyl metabolites in human urine and fecal samples using chemoselective modification
51 carbonyl-containing metabolites were validated in human urine and feces samples using an advanced chemoselective metabolite-capturing method for mass spectrometric analysis.
Paper spray mass spectrometry for the analysis of picoliter droplets
Paper spray ionization coupled with high resolution mass spectrometry is shown to be an effective strategy for the analysis of picoliter droplets containing atmospherically-relevant oxygenated organic compounds.
Electrodeposition behavior of homoleptic transition metal acetonitrile complexes interrogated with piezoelectric gravimetry
Homoleptic first-row transition metal acetonitrile complexes are shown to be precursors for metal electrodeposition from homogeneous solutions.
Online reaction monitoring by single-scan 2D NMR under flow conditions
Single-scan 2D NMR based on spatial encoding can be used to monitor chemical reactions with a flow unit in realistic reaction conditions.
Zero electrical power pump for portable high-performance liquid chromatography
A major trend in analytical chemistry is the miniaturization of laboratory instrumentation. We present a portable high-performance liquid chromatography system for field based chemical analyses.
CIRDES: an efficient genome-wide method for in vivo RNA–RNA interactome analysis
Complex RNA–RNA interactions underlie fundamental biological processes.
Ultrasensitive detection of lung cancer-associated miRNAs by multiple primer-mediated rolling circle amplification coupled with a graphene oxide fluorescence-based (MPRCA-GO) sensor
MPRCA-GO sensor can detect low amount of miRNAs, which are biomarkers in cancer diagnosis.
Subsecond detection of guanosine using fast-scan cyclic voltammetry
We present the first electrochemical characterization of guanosine, a purinergic neuromodulator and neuroprotector, using fast-scan cyclic voltammetry at carbon-fiber microelectrodes.
About this collection
Analyst is delighted to present this growing web collection showcasing some of the best research being conducted by early career scientists in the field of analytical chemistry. This series is edited by Laura Lechuga (Catalan Institute of Nanoscience and Nanotechnology, Spain), Ryan Bailey (University of Michigan, USA) and Jaebum Choo (Hanyang University, South Korea) and aims to highlight up-and-coming researchers in the early stages of the independent careers.
This collection is updated when new Emerging Investigator Series papers are published, so keep checking the page for new articles!
You can read our feature interviews with the corresponding authors included in the series on our blog. More details about the series and how to apply are available at rsc.li/analyst-emerging