Multiplexed detection of biomarkers in lateral-flow immunoassays
Multiplexed detection of biomarkers, i.e., simultaneous detection of multiple biomarkers in a single assay, can enhance diagnostic precision, improve diagnostic efficiency, reduce diagnostic cost, and alleviate pain of patients.
Paper-based SERS analysis with smartphones as Raman spectral analyzers
We present a smartphone-based portable Raman spectrometer, which has a friendly human–machine interface, easy operation, rapid response time, and most importantly a very small size for on-site use.
Dynamic pH measurements of intracellular pathways using nano-plasmonic assemblies
Functionalized plasmonic Ag nano-assemblies moving in a living cell were employed to visualize the spatiotemporal change of intracellular pH by surface-enhanced Raman scattering.
Rapid and specific duplex detection of methicillin-resistant Staphylococcus aureus genes by surface-enhanced Raman spectroscopy
A highly specific method for rapid detection of MRSA genes has been proposed by combining surface-enhanced Raman spectroscopy nanotags and magnetic isolation, which shows great potential for accurate identification of MRSA at an early-diagnosis stage.
Surface-enhanced spatially-offset Raman spectroscopy (SESORS) for detection of neurochemicals through the skull at physiologically relevant concentrations
Detection techniques for neurotransmitters that are rapid, label-free, and non-invasive are needed to move towards earlier diagnosis of neurological disease.
A rapid dual-channel readout approach for sensing carbendazim with 4-aminobenzenethiol-functionalized core–shell Au@Ag nanoparticles
In this study, a 4-aminobenzenethiol-functionalized silver-coated gold nanoparticle (Au@Ag-4ABT NP) system was designed for the rapid sensing of carbendazim (CBZ) using a combination of naked-eye colorimetry and SERS dual-channel approach.
Rapid differentiation of Campylobacter jejuni cell wall mutants using Raman spectroscopy, SERS and mass spectrometry combined with chemometrics
SERS was developed for intercellular and intracellular analyses. Using a series of cell wall mutants in C. jejuni we show cell wall versus cytoplasm differences.
Protein corona-resistant SERS tags for live cell detection of integrin receptors
Integrin receptors, important in chemical signaling, are imaged using SERS tags in fixed and live cancer cells providing insight into cell signaling and potential drug targets.
Paper
Direct monitoring of light mediated hyperthermia induced within mammalian tissues using surface enhanced spatially offset Raman spectroscopy (T-SESORS)
Here we demonstrate light mediated heating of nanoparticles confined deep inside mammalian tissue, whilst directly monitoring their temperature non-invasively using a form of deep Raman spectroscopy, T-SESORS.
A graphene oxide/gold nanoparticle-based amplification method for SERS immunoassay of cardiac troponin I
A multiple signal amplification of a SERS biosensor was developed for sensitive detection of cTnI with the aid of GO/AuNP complexes.
Highly sensitive detection of exosomes by SERS using gold nanostar@Raman reporter@nanoshell structures modified with a bivalent cholesterol-labeled DNA anchor
Exosomes, as important signal transmitters, play a key role in intercellular communication, especially in cancer metastasis.
PEGylated nanographene-mediated metallic nanoparticle clusters for surface enhanced Raman scattering-based biosensing
We demonstrate PEGylated nano-sized graphene-induced AuNP clusters, which could serve as SERS nanotags for highly sensitive SERS-based biosensing.
Surface enhanced Raman scattering sensor for highly sensitive and selective detection of ochratoxin A
An aptamer based SERS sensor was developed to detect picomolar concentrated ochratoxin solutions using an OPLS model.
About this collection
Professor Faulds has looked back at SERS papers published in Analyst over the last few years, and highlighted some of the most exciting and outstanding contributions for her Editor’s Choice collection. She adds that “it was very challenging to select this collection of representative articles due to the high number of excellent SERS articles published in Analyst. I hope you enjoy reading these articles as much as I did, and that these demonstrate the breadth and depth of SERS research published in Analyst; from multiplexed bioassays to imaging to SESORS.