Themed collection Analyst Review Articles 2021

This review focuses on electrochemical and spectroelectrochemical methods that have been developed and used specifically to chemically characterize bacteria and their behavior.

The direct modulation of a light-up aptamer that engenders an analyte-specific aptamer-light-up aptamer chimera is readily applicable in any diagnostic assay for a targeted detection.

The latest research on porous organic frameworks, as well as their multifunctional composites in the sample pretreatment for pesticide and veterinary drug residues, were comprehensively reviewed.

This minireview introduces the principles and recent applications of machine learning and experimental designs in developing and improving electrochemical sensors.

Research progress of MMIPs-optical sensors and MMIPs-electrochemical sensors based on biomarker detection.

Various construction protocols of PNAs-based electrochemical nucleic acid sensor enables the feasibility of rapid nucleic acid diagnosis in genetics, pathology, criminology, and food safety.

This review paper highlights the recent research on liquid-phase microscale separation techniques for lipidome analysis over the last 10 years, focusing on capillary liquid chromatography and capillary electrophoresis coupled with mass spectrometry.

This review describes recent progress of analytical techniques using vibrational spectroscopy and chemometrics for biological materials relevant to criminal investigation, including body fluids, hair, soft tissue, bones, and bioagents.

Raman spectroscopy (RS) is used to analyze the physiochemical properties of bone because it is non-destructive and requires minimal sample preparation.

Organic small molecule–based fluorescent probes for sensing pH change within specific organelles.

A comprehensive review of recent progress in inertial microfluidics with special focus on multistage cell separation and detection devices in addition to straight and curved channels.

The hybridization chain reaction is a very popular isothermal nucleic acid amplification technology.

This paper reviews recent advances in enrichment methods for circulating tumor cells (CTCs) with special attention to hybrid-modality methods.

Detection and recognition of chemical and biological species via sensor electronics are important not only for various sensing applications but also for fundamental scientific understanding.

The technological developments of high-speed spontaneous and coherent Raman scattering based imaging for translational applications including surgical guidance, histopathology, and pathophysiological monitoring.

This review focuses on the ophthalmic sensing technologies for ocular disease diagnosis. Both conventional methods and biosensing technologies are discussed accompany with smart readout devices. Future perspectives for tear diagnosis are claimed.

This review examines the principles of the LMJ-SSP interface and highlights modifications of the original design extending its capability. We summarize application areas and describe potential future directions for the adaptable ionization source.

Se occurrence in environment should be monitored, e.g. by electrochemical sensors. The diverse (nano)materials covered in the review interact strongly with selenium, and therefore, can be employed for selenium sensor development.

In this review we discuss surface enhanced Raman scattering (SERS) based techniques for the multiplexed detection of pathogenic microorganisms and their transition into point-of-use detection technologies in the field.

The high-performance liquid chromatography-mass spectrometry technique is subjected to drawbacks called matrix effects that could lead to ion suppression or ion enhancement.

In this review, we focus on the detection methods of full-length circular nucleic acids based on long-read sequencing technologies and the latest progress therein.

In this review, recent advances on the application of inertial microfluidics for cell analysis and detection are summarized.

Complete layout of a centrifugal microfluidic system.

We review the endeavors on the compositional and structural engineering of nanomaterials in the MS characterization of biomolecules in terms of enriching targets, enhancing the ionization efficiency and amplifying the ion signals.

Imaging mass spectrometry enables visualization of the neuroanatomical distribution of thousands of biochemicals in the human brain, providing a wealth of information for diagnostic, prognostic, and therapeutic developments for neuro diseases.

Here, we organize all the pictures that appear in the text separately.

The number of publications related to imaging flow cytometry.