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Themed collection In vivo analysis

21 items
Editorial

Editorial – in vivo analysis

This Editorial introduces Analyst's themed collection on In Vivo Analysis, guest edited by Lanqun Mao.

Graphical abstract: Editorial – in vivo analysis
From the themed collection: In vivo analysis
Minireview

A review of the effects of FSCV and microdialysis measurements on dopamine release in the surrounding tissue

We review the work of “voltammetry next to a microdialysis probe” as measured by dopamine and the surrounding tissue.

Graphical abstract: A review of the effects of FSCV and microdialysis measurements on dopamine release in the surrounding tissue
From the themed collection: Hot review articles in Analyst 2015
Minireview

Vesicular exocytosis and microdevices – microelectrode arrays

Among all the analytical techniques capable of monitoring exocytosis in real time at the single cell level, electrochemistry (particularly amperometry at a constant potential) using ultramicroelectrodes has been demonstrated to be an important and convenient tool for more than two decades.

Graphical abstract: Vesicular exocytosis and microdevices – microelectrode arrays
From the themed collection: Hot review articles in Analyst 2015
Minireview

Selected recent in vivo studies on chemical measurements in invertebrates

Review of in vivo analysis of brain chemicals in invertebrates.

Graphical abstract: Selected recent in vivo studies on chemical measurements in invertebrates
From the themed collection: In vivo analysis
Open Access Critical Review

A review of flux considerations for in vivo neurochemical measurements

The mass transport of neurochemicals in the brain and how this flux affects chemical measurements and data interpretation is reviewed.

Graphical abstract: A review of flux considerations for in vivo neurochemical measurements
From the themed collection: Hot review articles in Analyst 2015
Communication

Parts per billion detection of uranium with a porphyrinoid-containing nanoparticle and in vivo photoacoustic imaging

Chemical tools that can report radioactive isotopes would be of interest to the defense community.

Graphical abstract: Parts per billion detection of uranium with a porphyrinoid-containing nanoparticle and in vivo photoacoustic imaging
From the themed collection: In vivo analysis
Paper

Unilateral horizontal semicircular canal occlusion induces serotonin increase in medial vestibular nuclei: a study using microdialysis in vivo coupled with HPLC–ECD

Chromatograms of 5-HT in 20 μl microdialysate of MVN in the USSCO group (solid line), in the control group (dotted line) before surgery (black), and postoperative days one (red), three (blue), and five (green).

Graphical abstract: Unilateral horizontal semicircular canal occlusion induces serotonin increase in medial vestibular nuclei: a study using microdialysis in vivo coupled with HPLC–ECD
From the themed collection: In vivo analysis
Paper

In vivo histamine voltammetry in the mouse premammillary nucleus

A modified histamine selective waveform with fast scan cyclic voltametry provides a stimulation-locked and unique electrochemical signal towards histamine in vivo & in vitro.

Graphical abstract: In vivo histamine voltammetry in the mouse premammillary nucleus
From the themed collection: In vivo analysis
Paper

Optical diagnosis of the progression and reversal of CCl4-induced liver injury in rodent model using minimally invasive autofluorescence spectroscopy

Schematic representation of the degree of intoxicant-induced liver injury and regeneration and the minimally invasive analysis using autofluorescence spectral features.

Graphical abstract: Optical diagnosis of the progression and reversal of CCl4-induced liver injury in rodent model using minimally invasive autofluorescence spectroscopy
From the themed collection: In vivo analysis
Paper

A near-infrared fluorescent probe for the detection of hydrogen polysulfides biosynthetic pathways in living cells and in vivo

We present a new NIR fluorescent probe for the biosynthetic pathways of H2Sn in living cells and in vivo.

Graphical abstract: A near-infrared fluorescent probe for the detection of hydrogen polysulfides biosynthetic pathways in living cells and in vivo
From the themed collection: In vivo analysis
Paper

Development of an on-animal separation-based sensor for monitoring drug metabolism in freely roaming sheep

Lab-on-a-sheep: on-animal sensor using microdialysis coupled to microchip electrophoresis with electrochemical detection.

Graphical abstract: Development of an on-animal separation-based sensor for monitoring drug metabolism in freely roaming sheep
From the themed collection: In vivo analysis
Paper

Striatal dopamine release in a schizophrenia mouse model measured by electrochemical amperometry in vivo

This study demonstrated the unaltered dopamine release in the striatum in a schizophrenia model dysbindin−/− mice.

Graphical abstract: Striatal dopamine release in a schizophrenia mouse model measured by electrochemical amperometry in vivo
From the themed collection: In vivo analysis
Paper

Stabilization of Prussian blue with polyaniline and carbon nanotubes in neutral media for in vivo determination of glucose in rat brains

This study demonstrates a new electrochemical microbiosensor for selective in vivo monitoring of glucose in rat brains.

Graphical abstract: Stabilization of Prussian blue with polyaniline and carbon nanotubes in neutral media for in vivo determination of glucose in rat brains
From the themed collection: In vivo analysis
Paper

Electroanalysis of pM-levels of urokinase plasminogen activator in serum by phosphorothioated RNA aptamer

Electrochemical assay for the universal biomarker of several cancers, urokinase plasminogen activator, uPA, based on uPA-specific fluorinated RNA aptamer and methylene blue redox indicator, allows 1 pM uPA analysis in serum, making it practically useful for clinical applications.

Graphical abstract: Electroanalysis of pM-levels of urokinase plasminogen activator in serum by phosphorothioated RNA aptamer
From the themed collection: In vivo analysis
Paper

Real-time monitoring of H2O2 release from single cells using nanoporous gold microelectrodes decorated with platinum nanoparticles

We present a self-supported nanoporous gold/PtNPs microelectrode with the sub-nanomolar sensitivity to detect H2O2 release from single cells.

Graphical abstract: Real-time monitoring of H2O2 release from single cells using nanoporous gold microelectrodes decorated with platinum nanoparticles
From the themed collection: In vivo analysis
Paper

Loss of the preferential control over the striato-nigral direct pathway by striatal NMDA receptors in a rat model of Parkinson's disease

Changes in the striatal NMDA receptor-mediated control over striatofugal pathways in Parkinson's disease, as revealed by dual-probe microdialysis.

Graphical abstract: Loss of the preferential control over the striato-nigral direct pathway by striatal NMDA receptors in a rat model of Parkinson's disease
From the themed collection: In vivo analysis
Paper

In vivo and continuous measurement of bisulfide in the hippocampus of rat's brain by an on-line integrated microdialysis/droplet-based microfluidic system

An on-line and continuous approach was demonstrated for in vivo measurement of bisulfide in rat's brain.

Graphical abstract: In vivo and continuous measurement of bisulfide in the hippocampus of rat's brain by an on-line integrated microdialysis/droplet-based microfluidic system
From the themed collection: In vivo analysis
Paper

Mass spectrometric measurement of neuropeptide secretion in the crab, Cancer borealis, by in vivo microdialysis

Schematic representation of overall workflow for sampling secreted neuropeptides from the hemolymph by using a needle attached to a syringe or in vivo microdialysis.

Graphical abstract: Mass spectrometric measurement of neuropeptide secretion in the crab, Cancer borealis, by in vivo microdialysis
From the themed collection: In vivo analysis
Paper

A multi-enzyme microreactor-based online electrochemical system for selective and continuous monitoring of acetylcholine

This study demonstrates an online electrochemical system (OECS) for selective and continuous measurements of acetylcholine (ACh) through efficiently integrating in vivo microdialysis, a multi-enzyme microreactor and an electrochemical detector.

Graphical abstract: A multi-enzyme microreactor-based online electrochemical system for selective and continuous monitoring of acetylcholine
From the themed collection: In vivo analysis
Paper

A microelectrochemical biosensor for real-time in vivo monitoring of brain extracellular choline

A first generation Pt-based polymer enzyme composite biosensor developed for real-time neurochemical monitoring was characterised in vivo for sensitive and selective detection of choline.

Graphical abstract: A microelectrochemical biosensor for real-time in vivo monitoring of brain extracellular choline
From the themed collection: Alzheimer's Research Month 2016
Paper

A durable non-enzymatic electrochemical sensor for monitoring H2O2 in rat brain microdialysates based on one-step fabrication of hydrogels

A non-enzymatic electrochemical H2O2 sensor was developed by in situ fabrication of biocompatible chitosan hydrogels, in which a specific recognition molecule for H2O2 – thionine – was stably immobilized via one-step electrodeposition.

Graphical abstract: A durable non-enzymatic electrochemical sensor for monitoring H2O2 in rat brain microdialysates based on one-step fabrication of hydrogels
From the themed collection: In vivo analysis
21 items

About this collection

The issue is dedicated to the latest advances and developments in the area of in vivo analysis, including research articles and reviews in topics such as electrochemistry, fluorescence, photoacousic imaging and microdialysis. The issue was Guest Edited by Professor Lanqun Mao from the Institute of Chemistry, Chinese Academy of Sciences, read Professors Mao’s Editorial for an overview of this exciting area of research and the articles included in the issue.

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