Themed collection 150th Anniversary Collection: Electrochemistry and Electroanalytical Approaches

This minireview summarizes the recent advancements in impact electrochemistry-based biosensing over the past two to three years and provides insights into the future directions of this field.

This minireview introduces the principles and recent applications of machine learning and experimental designs in developing and improving electrochemical sensors.

Herein the development of cellular impedance biosensors, electrochemical impedance spectroscopy, and the general principles and terms associated with the cell–electrode interface is reviewed.

Combining affinity-based nanoswitches with state-dependent readout platforms allows for continuous biosensing and acquisition of real-time information about biochemical processes occurring in the environment of interest.

This paper presented the possibility of the in situ tuning of the LSPR properties of AuNRs@mSiO₂ by Hg deposition via electrochemical potential manipulations without the disturbance of the structural variations of AuNR cores.

The finte element simulation predicts that interactions of a biological membrane with a permeant can be determined quantitatively by employing transient scanning electrochemical microscopy to discriminate between one-step and two-step transport.

Here, we report a proof-of-concept resistive pulse method for analyzing chiral amino acids utilizing metal–amino acid crystallization differences.

The stable potential window (SPW) is the potential range that an electrode modified by a self-assembled monolayer (SAM) can operate without desorbing the SAM. Here we introduce SPWs for aromatic SAMs at Au.

Current healthcare trends have moved towards personalised precision medicine to tailor treatments to the individual in response to diseases and disease therapies. This reflects our electrochemical approach to monitoring leucovorin.

A novel cell tracking algorithm, named HFM-Tracker (Hybrid Feature Matching Tracker), is proposed to accurately track the migratory behavior of cells through the capture of time-lapse cell images.

The ion transfer current of perfluorooctanoate is modulated by its binding with BSA or β-cyclodextrin, enabling characterisation of those complexes.

AFM force spectroscopy is used to study the effects of electrochemically deposited silver nanoparticle-microspots on E. coli at the single-cell level. Optimization of the electrodeposition was conducted via scanning electrochemical cell microscopy.

New electrochemical probes offer the opportunity to investigate new systems. In this work, we provide a guide for how to fabricate dual barrel, Pt disk electrodes. We include data and procedures for characterizing and troubleshooting the electrodes.

Photopolymerization binds H⁺ ionophores covalently to poly(decyl methacrylate) sensing membranes of ion-selective electrodes. The membranes are at the same time covalently attached to the underlying inert polymer and the nanographite solid contact.

KOH treatment improves CFME and CNTYME sensitivity to five bioactive neurochemicals. The treatment etches and adds oxygen functional groups to the surface of the CFME, and it creates crevices and adds oxygen functional groups to the CNTYME.

Electropolymerized MIP (E-MIP) on disposable electrode for rapid and quantitative sub-nanomolar protein determination in serum using electrochemical impedance spectroscopy. Simple and rapid K_D determination for E-MIP.

An electrochemical immunoassay based on the redox cycling method was presented using vertically paired electrodes (VPEs), which were fabricated using PEDOT:PSS as an electrode material and parylene-C as a dielectric layer.

We report an enzyme conjugation method that can enhance the enzymatic activity by a tetrahedral DNA framework modification.

An electrochemical chiral sensing platform based on a multi-substituted ferrocene–Cu⁺ complex is constructed for the discrimination of electroactive amino acid isomers.

This study reports an osmium-based redox reporter that enables pH-insensitive and fast DNA-based molecular sensing, offering new possibilities for the study of short-lived dynamic molecular events.

A three-dimensional quantitative hydrogen distribution and state-of-charge distribution in a Ni–MH battery cathode can be acquired using laser-induced breakdown spectroscopy.

In this work, the electrochemical response of different morphologies (shapes) and dimensions of additively manufactured (3D-printing) carbon black(CB)/poly-lactic acid (PLA) electrodes are reported.

Design and production of a one-step 3D-printed functional electrochemical biosensor for efficient detection of dopamine and glucose in low-volume samples (100 μL). Glucose detection via ruthenium-mediated amperometry provides results in 60 seconds.

Here, we developed a microfluidic paper device by combining ion-selective electrodes (ISE) and a distance-based paper device (dPAD) for simultaneous potentiometric and colorimetric detection of urine electrolytes including K⁺, Na⁺ and Cl⁻.

We have repurposed industrial, standard printed circuit boards (PCBs) for DNA sensing and integrated them with an open-source portable potentiostat. This work paves the way towards low cost, miniaturized electronic systems for on-site testing.

A low-cost electrochemical paper-based analytical device was developed to quantify cancer cell-derived exosomes.

The bypass circuit with zinc wire induces spontaneous charge flow: oxidation of zinc and reduction of the solid contact of K-ISE. This effect is helpful in the improvement of analytical parameters of K-ISE.

Overcoming challenges associated with biological imaging by correlating hyperspectral imaging and scanning electrochemical microscopy; this powerful combination provides unambiguous determination of cell boundaries for studying cellular dynamics.

Electrochemical problems are widely studied in flowing systems since the latter offer improved sensitivity notably for electro-analysis and the possibility of steady-state measurements for fundamental studies even with macro-electrodes.

The development of flexible substrate materials and nanomaterials with high electrochemical performance is of great significance for constructing efficient wearable electrochemical sensors for real-time health monitoring.

The unprecedented role of carbon nanotubes in promoting and sensing enzymatic oxidation of polycyclic aromatic hydrocarbons by laccases enables femtomolar detection of anthracene.

A poly-nordihydroguaiaretic acid film is employed as a voltammetric indicator for bound/unbound boronic acid sites to report on glucose and fructose concentration.

We have designed and synthesized a multifunctional dendritic molecular probe that selectively detects Cu²⁺ ions via potentiometric and fluorometric techniques with low detection limits (3.5 μM in potentiometry, 15 nM in fluorometry).

CdS quantum dot (QD) modified nanopipette was prepared for the PEC analysis of the alkaline phosphatase (ALP) activity in single MCF-7 cells.

Matrix metalloproteinase-1 (MMP-1) is associated with many types of cancers, including oral, colorectal, and brain cancers.

An electrochemical biosensor employing a gold nanoparticles/graphene quantum dots/graphene oxide composite modified electrode is developed for the multiplex detection of miRNA breast cancer biomarkers.

We propose a “plug-and-play” (PnP) assembly for coupling paper-based colorimetric and electrochemical devices for multiplexed detection of metals.

The abuse of methamphetamine (MA) is to date detected and subsequently verified through the monitoring of MA and its metabolites within biological specimens.

A novel ratiometric electrochemical biosensing strategy based on T7 exonuclease-assisted homogenous target recycling coupling hairpin assembly-triggered dual-signal output was designed for the accurate and sensitive detection of microRNA-141.

A novel dopamine targeted electrochemical detection strategy has enabled the phenotyping and non-invasive monitoring of human midbrain organoids (healthy and Parkinson's diseased), by employing a redox-cycling based microsensor.

Guanine (G) oxidation products, such as 8-hydroxy-2′-deoxyguanosine (8-OHdG) and 8-oxo-guanine (8-OXOG), have been widely studied as promising biomarkers for DNA oxidative damage.

A fast EQCM measures the kinetics of the viscosity changes inside the double layer following voltage jumps.

The process for simultaneous analysis of five metal ions with one device by using Bc, PAR, DTZ, PAR, and DMG for Cu(II), Co(II), Hg(II), Mn(II), and Ni(II) detection, respectively.

Cocaine samples were ‘finger-printed’ using e-MIPs, constructed on the surface of portable SPCEs. The SWV data with suitable chemometric analysis provides valuable information about the drugs’ provenience which is crucial to tackle drug traffic.

The ITIES was used to study the interfacial behavior of 5 carbosilane dendrimers terminated with imidazolium groups. We have found that these chemical species undergo ion transfer reactions coupled to interfacial adsorption/desorption processes.

A glassy carbon electrode chemically modified with a carbon black coating is proposed here for the rapid and portable determination of cannabidiol (CBD) in a commercial Cannabis seed oil and in fibre-type Cannabis sativa L. leaves.