Jump to main content
Jump to site search


Synthesis of Aryl-Substituted 2-Methoxyphenol Derivatives from Maltol-Derived Oxidopyrylium Cycloadducts through an Acid-Mediated Ring Contraction Cascade

Abstract

Oxidopyrylium cycloadducts derived from maltol and aryl acetylenes undergo acid-mediated rearrangements to generate aryl-substituted 2-methoxyphenol (guaiacol) derivatives. Specifically, the cycloadducts react with boron trichloride to form 2-methoxy-5-arylphenol molecules, and with methane sulfonate to form 2-methoxy-4-aryl-6-methylphenol molecules.

Back to tab navigation

Supplementary files

Article information


Submitted
26 Nov 2019
Accepted
07 Jan 2020
First published
07 Jan 2020

Chem. Commun., 2020, Accepted Manuscript
Article type
Communication

Synthesis of Aryl-Substituted 2-Methoxyphenol Derivatives from Maltol-Derived Oxidopyrylium Cycloadducts through an Acid-Mediated Ring Contraction Cascade

L. P. Bejcek and R. P. Murelli, Chem. Commun., 2020, Accepted Manuscript , DOI: 10.1039/C9CC09213G

Social activity

Search articles by author

Spotlight

Advertisements