Propargylamine-selective dual fluorescence turn-on method for post-synthetic labeling of DNA

Van Thang Nguyen; Anup Pandith; Young Jun Seo

doi:10.1039/D0CC00255K

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Propargylamine-selective dual fluorescence turn-on method for post-synthetic labeling of DNA†

Van Thang Nguyen,^a Anup Pandith

^b and Young Jun Seo

*^ab

Author affiliations

* Corresponding authors

^a Department of Bioactive Material Sciences, Jeonbuk National University, South Korea

^b Department of Chemistry, Jeonbuk National University, South Korea
E-mail: yseo@jbnu.ac.kr
Fax: +82-63-270-3408
Tel: +82-63-270-3417

Abstract

We have developed a propargylamine-selective dual fluorescence turn-on system, using ylidenemalononitrile enamines, for post-synthetic DNA labeling, allowing the direct monitoring of DNA using dual emission in living cells.

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Article information

DOI: https://doi.org/10.1039/D0CC00255K
Article type: Communication
Submitted: 10 Jan 2020
Accepted: 03 Feb 2020
First published: 04 Feb 2020

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Chem. Commun., 2020,56, 3199-3202

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Propargylamine-selective dual fluorescence turn-on method for post-synthetic labeling of DNA

V. T. Nguyen, A. Pandith and Y. J. Seo, Chem. Commun., 2020, 56, 3199 DOI: 10.1039/D0CC00255K

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Chemical Communications

Propargylamine-selective dual fluorescence turn-on method for post-synthetic labeling of DNA†

Abstract

Supplementary files

Article information

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Propargylamine-selective dual fluorescence turn-on method for post-synthetic labeling of DNA

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