Controlling the release of hydrophobic compounds by a supramolecular amphiphilic assembly

Ruslan R. Kashapov; Regina I. Rassadkina; Albina Yu. Ziganshina; Rezeda K. Mukhitova; Vakhid A. Mamedov; Nataliya A. Zhukova; Marsil K. Kadirov; Irek R. Nizameev; Lucia Ya. Zakharova; Oleg G. Sinyashin

doi:10.1039/C6RA03838G

Controlling the release of hydrophobic compounds by a supramolecular amphiphilic assembly†

Ruslan R. Kashapov,*^ab Regina I. Rassadkina,^b Albina Yu. Ziganshina,^a Rezeda K. Mukhitova,^a Vakhid A. Mamedov,^ab Nataliya A. Zhukova,^ab Marsil K. Kadirov,^ab Irek R. Nizameev,^ab Lucia Ya. Zakharova^ab and Oleg G. Sinyashin^ab

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* Corresponding authors

^a A. E. Arbuzov Institute of Organic and Physical Chemistry, Kazan Scientific Center, Russian Academy of Sciences, 8 Arbuzov Str., Kazan 420088, Russia
E-mail: kashapov@iopc.ru

^b Kazan National Research Technological University, 68 Karl Marx Str., Kazan 420015, Russia

Abstract

Here, we report a novel approach of using a supramolecular system based on calix[4]resorcinarene and surfactant to facilitate the release of hydrophobic compounds. This finding is an important step towards the development of controlled-release formulations for water-insoluble drugs.

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Controlling the release of hydrophobic compounds by a supramolecular amphiphilic assembly†

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Controlling the release of hydrophobic compounds by a supramolecular amphiphilic assembly

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