Issue 45, 2016, Issue in Progress
From the journal:

RSC Advances

A telescopic one-pot synthesis of β-lactam rings using amines as a convenient source of imines†

Suvi H. M. Rajamäki,a   Lidia De Luca,a   Francesca Capittaa  and  Andrea Porcheddu*b  

* Corresponding authors

a Università degli Studi di Sassari, Dipartimento di Chimica e Farmacia, via Vienna 2, Sassari, Italy

b Università degli Studi di Cagliari, Dipartimento di Scienze Chimiche e Geologiche, Cittadella Universitaria, SS 554 bivio per Sestu, 09042 Monserrato, Ca, Italy
E-mail: porcheddu@unica.it

Abstract

A facile synthetic approach to substituted β-lactams was designed, using secondary benzylic amines and acid chlorides as starting materials. The reactions proceeded smoothly and all the products were obtained in good yields.

Graphical abstract: A telescopic one-pot synthesis of β-lactam rings using amines as a convenient source of imines

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Article information

DOI
https://doi.org/10.1039/C6RA02744J
Article type
Communication
Submitted
29 Jan 2016
Accepted
12 Apr 2016
First published
14 Apr 2016

RSC Adv., 2016,6, 38553-38557

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A telescopic one-pot synthesis of β-lactam rings using amines as a convenient source of imines

S. H. M. Rajamäki, L. De Luca, F. Capitta and A. Porcheddu, RSC Adv., 2016, 6, 38553 DOI: 10.1039/C6RA02744J

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