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Issue 13, 2015

Biosensing by luminogens with aggregation-induced emission characteristics

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Abstract

Fluorescent biosensors are powerful analytical tools for studying biological events in living systems. Luminescent materials with aggregation-induced emission (AIE) attributes have attracted much research interest and have been identified as a novel class of luminogens to develop fluorescent turn-on biosensors with superior sensitivity. In this Tutorial Review, we present an overview of the AIE phenomenon and its mechanism. We summarize the structural design and working principle of AIE biosensors developed recently. Typical examples of AIE biosensors are presented.

Graphical abstract: Biosensing by luminogens with aggregation-induced emission characteristics

Supplementary files

Article information


Submitted
29 Sep 2014
First published
06 Nov 2014

Chem. Soc. Rev., 2015,44, 4228-4238
Article type
Tutorial Review
Author version available

Biosensing by luminogens with aggregation-induced emission characteristics

R. T. K. Kwok, C. W. T. Leung, J. W. Y. Lam and B. Z. Tang, Chem. Soc. Rev., 2015, 44, 4228 DOI: 10.1039/C4CS00325J

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