Issue 55, 2014
From the journal:

RSC Advances

Effect of surface properties in protein corona development on mesoporous silica nanoparticles†

Alden M. Clemments,a   Carlos Muniesa,b   Christopher C. Landry*a  and  Pablo Botella*b  

* Corresponding authors

a Department of Chemistry, University of Vermont, Burlington, USA
E-mail: christopher.landry@uvm.edu

b Instituto de Tecnología Química (UPV-CSIC), Av. Los Naranjos s/n, 46022 Valencia, Spain
E-mail: pbotella@itq.upv.es

Abstract

The composition of the protein corona formed on mesoporous silica nanoparticles with several surface modifications was characterized. Low MW serum proteins were preferentially adsorbed, and PEGylated nanoparticles did not adsorb protein regardless of PEG chain length.

Graphical abstract: Effect of surface properties in protein corona development on mesoporous silica nanoparticles

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Article information

DOI
https://doi.org/10.1039/C4RA03277B
Article type
Communication
Submitted
11 Apr 2014
Accepted
18 Jun 2014
First published
18 Jun 2014

RSC Adv., 2014,4, 29134-29138

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Effect of surface properties in protein corona development on mesoporous silica nanoparticles

A. M. Clemments, C. Muniesa, C. C. Landry and P. Botella, RSC Adv., 2014, 4, 29134 DOI: 10.1039/C4RA03277B

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