Issue 2, 1989

A reversible inhibitor of β-lactamase I from Bacillus cereus

Abstract

α-Methyl (3S,5R,6R)benzylpenicilloate is a reversible competitive inhibitor of β-lactamase l from Bacillus cereus; the inhibition constant Ki is 6.38 × 10–4M and is independent of pH between pH 5 and 8 which is compatible with binding of the free base form of the thiazolidine residue to the enzyme.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1989, 70-71

A reversible inhibitor of β-lactamase I from Bacillus cereus

M. Jones, S. C. Buckwell, M. I. Page and R. Wrigglesworth, J. Chem. Soc., Chem. Commun., 1989, 70 DOI: 10.1039/C39890000070

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