Issue 19, 1983

Stereoselective synthesis of α-methylene-β-hydroxy-γ-alkoxy esters from α-alkoxy aldehydes

Abstract

The Reformatsky-type condensation between methyl and t-butyl 3-(N,N-dimethylamino)propionates (9) and (10) with α-alkoxy aldehydes, which has been studied on varying the protective group of the aldehyde, proceeds with good diastereoselectivity.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1983, 1112-1113

Stereoselective synthesis of α-methylene-β-hydroxy-γ-alkoxy esters from α-alkoxy aldehydes

L. Banfi, L. Colombo, C. Gennari and C. Scolastico, J. Chem. Soc., Chem. Commun., 1983, 1112 DOI: 10.1039/C39830001112

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