Chiral amplification of prebiotic peptide synthesis induced by chemical–physical interactions on calcite surfaces

Abstract

Understanding how life substances adopted a single configuration under prebiotic conditions is central to exploring the origins of homochirality. This study shows a chiral amplification effect during prebiotic peptide synthesis on calcite surfaces, driven by the synergy between chemical synthesis and physical adsorption. This chemical–physical coupling mechanism offers a unique and promising strategy for promoting the emergence of homochirality.