Correction: Synergic therapy of melanoma using GNRs-MUA-PEI/siIDO2-FA through targeted gene silencing and plasmonic photothermia

Yujuan Zhang; Na Song; Jiamin Fu; Yanling Liu; Xuelin Zhan; Shanshan Peng; Zhi Yang; Xianfang Zhu; Yiguo Chen; Zhigang Wang; Yanrong Yu; Qiaofa Shi; Yingyuan Fu; Keng Yuan; Nanjin Zhou; Thomas E. Ichim; Weiping Min

doi:10.1039/C6RA90075E

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DOI: 10.1039/C6RA90075E (Correction) RSC Adv., 2016, 6, 79236-79237

Correction: Synergic therapy of melanoma using GNRs-MUA-PEI/siIDO2-FA through targeted gene silencing and plasmonic photothermia

Yujuan Zhang*^ab, Na Song^ab, Jiamin Fu^ab, Yanling Liu^ab, Xuelin Zhan^ab, Shanshan Peng^ab, Zhi Yang^ab, Xianfang Zhu^c, Yiguo Chen^ab, Zhigang Wang^ab, Yanrong Yu^ab, Qiaofa Shi^a, Yingyuan Fu^a, Keng Yuan^ab, Nanjin Zhou^ab, Thomas E. Ichim^d and Weiping Min*^abe
^aInstitute of Immunotherapy and College of Basic Medicine, Nanchang University, Jiangxi Academy of Medical Sciences, Nanchang, China. E-mail: yujuanzhang@ncu.edu.cn
^bJiangxi Provincial Key Laboratory of Immunotherapy, Nanchang, China
^cChina-Australia Joint Laboratory for Functional Nanomaterials, School of Physics and Mechanical and Electrical Engineering, Xiamen University, Xiamen, China
^dBatu Biologics Inc, San Diego, California, USA
^eDepartment of Surgery, Pathology and Oncology, University of Western Ontario, London, Canada. E-mail: mweiping@uwo.ca

Received 16th August 2016 , Accepted 16th August 2016

First published on 22nd August 2016

Abstract

Correction for ‘Synergic therapy of melanoma using GNRs-MUA-PEI/siIDO2-FA through targeted gene silencing and plasmonic photothermia’ by Yujuan Zhang et al., RSC Adv., 2016, 6, 77577–77589.

The authors regret that Fig. 6 in the original manuscript requires correction. The titles for subparts ‘a’ and ‘d’ within Fig. 6C should state ‘PBS’ and ‘PBS+Laser’ rather than ‘BSA’ and ‘BSA+Laser’, respectively. The amended figure is shown below.


	Fig. 6 In vitro photothermal effects of GNR-MUA-PEI-FA and GNR-MUA-PEI/siIDO2-FA. B16-BL6 cells were incubated with a final concentration of 15 μg mL⁻¹ of GNR-MUA-PEI-FA or PBS overnight. Subsequently, the cells were irradiated at (A) 2 W cm⁻² for various times (0 minutes, 0.5 minutes, 1 minute, 2 minutes, 5 minutes, 10 minutes) or for (B) 5 minutes with different power densities (0 W cm⁻², 0.5 W cm⁻², 1 W cm⁻², 2 W cm⁻², 4 W cm⁻²). After 24 hours, the cell viabilities were measured by the MTT assay and the percentages of dead cells = (cell viabilities before laser irradiation − cell viabilities after laser irradiation)/(cell viabilities before laser irradiation). (C) Apoptosis of tumor cells induced by GNR-MUA-PEI/siIDO2-FA. B16-BL6 cells were incubated with PBS (a) or GNR-MUA-PEI/siGL2-FA (b), or GNR-MUA-PEI-FA-siIDO2 (c), at the final concentration of 16 μg mL⁻¹ of wt ((GNR-MUA-PEI-FA):wt(siIDO2) = 15:1) overnight. Cells were either not irradiated (a–c) or were irradiated (d–f) at 2 W cm⁻² for 5 minutes using a laser with a wavelength of 808 nm. The apoptotic and necrotic cell populations were determined at 24 hours by Annexic V-FITC/PI Apoptosis Detection Kit and analyzed by flow cytometry. Error bars represent the standard deviation of 3 experiments.

The Royal Society of Chemistry apologises for these errors and any consequent inconvenience to authors and readers.

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