Construction of a turn-on probe for fast detection of H2S in living cells based on a novel H2S trap group with an electron rich dye

Abstract

A turn-on probe (ANR) for fast detection of H₂S is constructed based on a 2-(azidomethyl)-4-nitrobenzoate moiety as a trap group. This group is very effective for the design of H₂S probes especially with electron rich dyes. The potential biological applications of ANR were proved by employing it for fluorescence imaging of H₂S in living cells.