Themed collection Biomaterials Science Recent HOT Articles

58 items
Minireview

Nanoscale metal–organic frameworks for the intracellular delivery of CRISPR/Cas9 genome editing machinery

The discovery of CRISPR/Cas9 genome-editing technology enables the precise manipulation of mammalian DNA sequences for treating genetic disorders.

Graphical abstract: Nanoscale metal–organic frameworks for the intracellular delivery of CRISPR/Cas9 genome editing machinery
From the themed collection: Biomaterials Science Recent HOT Articles
Minireview

Application and research progress of phase change materials in biomedical field

Application of phase change materials (PCMs) in biomedical field.

Graphical abstract: Application and research progress of phase change materials in biomedical field
From the themed collection: Biomaterials Science Recent HOT Articles
Minireview

In situ self-assembled peptide nanofibers for cancer theranostics

Nanofibers constructed by an in situ self-assembly strategy hold tremendous promise for cancer theranostics with characteristic functions and biological effects in different parts of tumor tissue.

Graphical abstract: In situ self-assembled peptide nanofibers for cancer theranostics
From the themed collection: Biomaterials Science Recent HOT Articles
Review Article

Nanoparticle based medicines: approaches for evading and manipulating the mononuclear phagocyte system and potential for clinical translation

Nanomedicine recognition and clearance by the mononuclear phagocyte system (MPS) impedes optimal clinical impacts for this class of materials. We present an overview of factors involved in MPS interactions and approaches to overcome this barrier.

Graphical abstract: Nanoparticle based medicines: approaches for evading and manipulating the mononuclear phagocyte system and potential for clinical translation
From the themed collection: Biomaterials Science Recent HOT Articles
Review Article

Engineering of protein crystals for use as solid biomaterials

Protein crystal engineering both in vitro and within cells has led to advances in protein crystallization and generation of solid functional materials.

Graphical abstract: Engineering of protein crystals for use as solid biomaterials
From the themed collection: Biomaterials Science Recent HOT Articles
Review Article

Recent developments in mussel-inspired materials for biomedical applications

Over the decades, researchers have strived to synthesize and modify nature-inspired biomaterials, with the primary aim to address the challenges of designing functional biomaterials for regenerative medicine and tissue engineering.

Graphical abstract: Recent developments in mussel-inspired materials for biomedical applications
From the themed collection: Biomaterials Science Recent HOT Articles
Review Article

Deoxyribonucleic acid anchored on cell membranes for biomedical application

This review provides an overview of engineering cellular membranes with deoxyribonucleic acids to manipulate cellular behaviors and functionalities for biomedical applications. The current challenges and future directions are summarized and proposed.

Graphical abstract: Deoxyribonucleic acid anchored on cell membranes for biomedical application
From the themed collection: Biomaterials Science Recent HOT Articles
Review Article

Marine origin materials on biomaterials and advanced therapies to cartilage tissue engineering and regenerative medicine

This comprehensive review brings a larger perspective on the most recent developments in new tissue-scaffolds based on marine origin polymers envisaging the treatment and repair of human articular cartilage tissues.

Graphical abstract: Marine origin materials on biomaterials and advanced therapies to cartilage tissue engineering and regenerative medicine
From the themed collection: Biomaterials Science Recent HOT Articles
Open Access Review Article

Recent progress in nanotechnology-based drug carriers for celastrol delivery

Various types of celastrol nanoformulations have been developed to treat a number of disorders, including cancer, inflammatory, auto-immune, obesity.

Graphical abstract: Recent progress in nanotechnology-based drug carriers for celastrol delivery
From the themed collection: Biomaterials Science Recent HOT Articles
Communication

DNA-coated gold nanoparticles for tracking hepatocyte growth factor secreted by transplanted mesenchymal stem cells in pulmonary fibrosis therapy

Based on the fluorescence off–on principle, a dye-labeled Au nanoflare tracer is presented for in vivo tracking the secretion of hepatocyte growth factor (HGF) by MSCs during idiopathic pulmonary fibrosis (IPF) therapy.

Graphical abstract: DNA-coated gold nanoparticles for tracking hepatocyte growth factor secreted by transplanted mesenchymal stem cells in pulmonary fibrosis therapy
From the themed collection: Biomaterials Science Recent HOT Articles
Communication

Facile synthesis of dendrimer like mesoporous silica nanoparticles to enhance targeted delivery of interleukin-22

Interleukin (IL)-22 is a multifunctional cytokine with a very short half-life that activates STAT3 and can elicit an anti-inflammatory response. We show encapsulation of IL-22 in LPMSN enhances its biological activity and stability in in vitro and human colonic organoids.

Graphical abstract: Facile synthesis of dendrimer like mesoporous silica nanoparticles to enhance targeted delivery of interleukin-22
From the themed collection: Biomaterials Science Recent HOT Articles
Communication

Non-contact measurement of internal body temperature using subcutaneously implanted diamond microparticles

We demonstrate the feasibility of subcutaneously implanted fluorescent diamond microparticles as a temperature probe for the non-contact measurement of internal body temperature using a homemade wide-field optically detected magnetic resonance imager.

Graphical abstract: Non-contact measurement of internal body temperature using subcutaneously implanted diamond microparticles
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Development and optimization of an ocular hydrogel adhesive patch using definitive screening design (DSD)

Bioadhesive hydrogel patches based on chemically modified photocrosslinkable polymers with specific physicochemical properties for sealing and repair of ocular injuries.

Graphical abstract: Development and optimization of an ocular hydrogel adhesive patch using definitive screening design (DSD)
Paper

Fibroblast-targeting polymeric nanovehicles to enhance topical wound healing through promotion of PAR-2 receptor-mediated endocytosis

A smart skin regeneration platform that can enhance their selective cellular uptake to fibroblasts via PAR-2 receptor mediated endocytosis is proposed.

Graphical abstract: Fibroblast-targeting polymeric nanovehicles to enhance topical wound healing through promotion of PAR-2 receptor-mediated endocytosis
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Tumor-targeting oxidative stress nanoamplifiers as anticancer nanomedicine with immunostimulating activity

GSH depleting prodrugs and ROS generators self-assemble to generate oxidative stress nanoamplifiers that can preferentially kill cancer cells and exert immunostimulating activity.

Graphical abstract: Tumor-targeting oxidative stress nanoamplifiers as anticancer nanomedicine with immunostimulating activity
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Photoclick polysaccharide-based bioinks with an extended biofabrication window for 3D embedded bioprinting

The proposed photoclick HC–HN bioink expands the palette of available polysaccharide-based bioinks and greatly extends the biofabrication window to broaden the application opportunities of 3D bioprinting.

Graphical abstract: Photoclick polysaccharide-based bioinks with an extended biofabrication window for 3D embedded bioprinting
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

In situ forming injectable γ-poly(glutamic acid)/PEG adhesive hydrogels for hemorrhage control

An injectable adhesive hydrogel based on N-hydroxysuccinimide γ-poly(glutamic acid) and 4-armed poly(ethylene glycol) amine showed rapid gelation time, strong mechanical strength, satisfactory burst pressure and excellent hemostatic performance.

Graphical abstract: In situ forming injectable γ-poly(glutamic acid)/PEG adhesive hydrogels for hemorrhage control
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Orally administrable polyphenol-based nanoparticles achieve anti-inflammation and antitumor treatment of colon diseases

Flash nanotechnology-produced nanomedicines exhibit potent antioxidant and anti-inflammatory properties and could overcome mucosal barrier for oral delivery, resulting in great efficiency in the prevention and treatment of colitis-associated colorectal cancer.

Graphical abstract: Orally administrable polyphenol-based nanoparticles achieve anti-inflammation and antitumor treatment of colon diseases
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

A component-optimized chemo-dynamic nanoagent for enhanced tumour cell-selective chemo-dynamic therapy with minimal side effects in a glioma mouse model

A component-optimized chemo-dynamic nanoagent achieved an enhanced tumour cell-selective chemo-dynamic therapy with minimal side effects in a glioma mouse model.

Graphical abstract: A component-optimized chemo-dynamic nanoagent for enhanced tumour cell-selective chemo-dynamic therapy with minimal side effects in a glioma mouse model
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Biodegradable peptide polymers as alternatives to antibiotics used in aquaculture

Biodegradable peptide polymers display potent and broad-spectrum antibacterial activity in vitro, as well as strong therapeutic potential in vivo, as a promising alternative to antibiotics in aquaculture.

Graphical abstract: Biodegradable peptide polymers as alternatives to antibiotics used in aquaculture
Paper

Functionalized boron nanosheets with near-infrared-triggered photothermal and nitric oxide release activities for efficient antibacterial treatment and wound healing promotion

A multifunctional nanoplatform has been developed based on boron nanosheets loaded quaternized chitosan and NO donor N,N′-di-sec-butyl-N,N′-dinitroso-1,4-phenylenediamine for rapid, and effective treatment of pathogenic bacteria.

Graphical abstract: Functionalized boron nanosheets with near-infrared-triggered photothermal and nitric oxide release activities for efficient antibacterial treatment and wound healing promotion
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Plant-inspired Pluronic–gallol micelles with low critical micelle concentration, high colloidal stability, and protein affinity

Plant-inspired gallol-containing surfactants have been successfully incorporated into typical Pluronic® micelles, allowing low critical micelle concentration, great colloidal stability, and exterior enzyme resistance.

Graphical abstract: Plant-inspired Pluronic–gallol micelles with low critical micelle concentration, high colloidal stability, and protein affinity
From the themed collection: Biomaterials Science Recent HOT Articles
Open Access Paper

Enhanced human T cell expansion with inverse opal hydrogels

Lymph node-inspired 3D hydrogels with precisely defined porosity were produced, which improve the state-of-the-art T cell proliferation, a procedure that is especially important for novel cellular immunotherapies.

Graphical abstract: Enhanced human T cell expansion with inverse opal hydrogels
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

The enhanced antitumor activity of the polymeric conjugate covalently coupled with docetaxel and docosahexaenoic acid

The polymer dual drug conjugate synthesized by coupling docetaxel (DTX) and docosahexaenoic acid (DHA) with bifunctionalized dextran is selectively accumulated in tumor and nearly eradicates all MCF-7 tumors bearing in nude mice.

Graphical abstract: The enhanced antitumor activity of the polymeric conjugate covalently coupled with docetaxel and docosahexaenoic acid
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Fatty acid-based polymeric micelles to ameliorate amyloidogenic disorders

Fatty acid-tethered polymers were synthesized via RAFT method to explore their potential role in preventing insulin aggregation process. The results endowed fatty acid-tethered polymers with properties to act as novel anti-amyloidogenic agents.

Graphical abstract: Fatty acid-based polymeric micelles to ameliorate amyloidogenic disorders
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Tailored therapeutic release from polycaprolactone-silica hybrids for the treatment of osteomyelitis: antibiotic rifampicin and osteogenic silicates

Polycaprolactone/silica hybrids offer a dual therapeutic effect: the promotion of bone regeneration thanks to silicate ions and strong antibacterial properties against the risk of osteomyelitis.

Graphical abstract: Tailored therapeutic release from polycaprolactone-silica hybrids for the treatment of osteomyelitis: antibiotic rifampicin and osteogenic silicates
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Near-infrared aggregation-induced emission nanodots for early diagnosis of tongue squamous cell carcinoma and sentinel lymph node mapping

By developing DPA-TPE-DCM with intense near-infrared fluorescence emission in the aggregation state, AIE materials were used for the first time in the early diagnosis of orthotopic TSCC and SLN mapping in an orthotopic TSCC-bearing mouse model.

Graphical abstract: Near-infrared aggregation-induced emission nanodots for early diagnosis of tongue squamous cell carcinoma and sentinel lymph node mapping
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Development of anticancer peptides with low hemolysis, high penetrating membrane activity, certain analgesic activity and the synergistic anticancer effect

Amphiphilic cationic anticancer lipopeptide P10 self-assembles into spherical aggregates, which are used as drug carriers to play a synergistic anticancer role, and its anticancer mechanism is presented.

Graphical abstract: Development of anticancer peptides with low hemolysis, high penetrating membrane activity, certain analgesic activity and the synergistic anticancer effect
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Bionic biphasic composite scaffolds with osteochondrogenic factors for regeneration of full-thickness osteochondral defects

A bionic biphasic composite scaffold with on-demand osteochondrogenic factors facilitated the regeneration of osteochondral defects.

Graphical abstract: Bionic biphasic composite scaffolds with osteochondrogenic factors for regeneration of full-thickness osteochondral defects
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Local delivery of naringin in beta-cyclodextrin modified mesoporous bioactive glass promotes bone regeneration: from anti-inflammatory to synergistic osteogenesis and osteoclastogenesis

The local delivery of naringin in beta-cyclodextrin modified mesoporous bioactive glass promotes bone regeneration via synergistic immunomodulation of osteogenesis and osteoclastogenesis by macrophages.

Graphical abstract: Local delivery of naringin in beta-cyclodextrin modified mesoporous bioactive glass promotes bone regeneration: from anti-inflammatory to synergistic osteogenesis and osteoclastogenesis
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Self-assembly of Fmoc-amino acids in capillary confined space forming a parallel ordered fiber network for application in vascularization

In this work, capillary tubes with different diameters were chosen to mimic a confined environment and the effect of space on the self-assembly behavior of short peptides with different oil-water partition coefficients (log P) was investigated.

Graphical abstract: Self-assembly of Fmoc-amino acids in capillary confined space forming a parallel ordered fiber network for application in vascularization
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

A theranostic microneedle array patch for integrated glycemia sensing and self-regulated release of insulin

We have designed a dual-function microneedle patch that integrates treatment and diagnosis.

Graphical abstract: A theranostic microneedle array patch for integrated glycemia sensing and self-regulated release of insulin
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Bioactive PCL microspheres with enhanced biocompatibility and collagen production for functional hyaluronic acid dermal fillers

Polymeric microspheres containing magnesium hydroxide (MH) and a bioactive agent (BA), such as apocynin (APO) and astaxanthin (ATX), have been prepared as functional dermal fillers with enhanced physicochemical and biological performance.

Graphical abstract: Bioactive PCL microspheres with enhanced biocompatibility and collagen production for functional hyaluronic acid dermal fillers
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Medical gloves modified by a one-minute spraying process with blood-repellent, antibacterial and wound-healing abilities

A kind of blood-repellent mist spray (MS) was proposed to prevent blood adhesion during surgery and played an important role in antibacterial and wound-healing, which could be widely used in the surface modification of various medical gloves.

Graphical abstract: Medical gloves modified by a one-minute spraying process with blood-repellent, antibacterial and wound-healing abilities
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Enhancement of intercellular interaction between iPSC-derived neural progenitor cells and activated endothelial cells using cell surface modification with functional oligopeptides

Stroke activated Endothelial Cells recruit leucocytes for further necrosis. Esbp-PEG-lipid modified cells can bind to these ECs for a rather protective effect and reduced leucocyte binding.

Graphical abstract: Enhancement of intercellular interaction between iPSC-derived neural progenitor cells and activated endothelial cells using cell surface modification with functional oligopeptides
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Facile discovery of a therapeutic agent for NK-mediated synergistic antitumor effects using a patient-derived 3D platform

3D tumor spheroid/NK co-culture platform facilitates the discovery of a small drug, C19, for synergistic NK-mediated cytolysis against pancreatic cancer patient-derived cancer spheroid.

Graphical abstract: Facile discovery of a therapeutic agent for NK-mediated synergistic antitumor effects using a patient-derived 3D platform
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Nanodot-doped peptide hydrogels for antibacterial phototherapy and wound healing

Antimicrobial peptide hydrogels combined with phototherapy in the treatment of infected wounds.

Graphical abstract: Nanodot-doped peptide hydrogels for antibacterial phototherapy and wound healing
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Planar organization of airway epithelial cell morphology using hydrogel grooves during ciliogenesis fails to induce ciliary alignment

Here we align airway epithelial cells on hydrogel grooves and induce apical-basal polarization and cilia formation. Neither initial alignment, nor maintained alignment on the grooves induced polarized cilia alignment in the epithelial sheet.

Graphical abstract: Planar organization of airway epithelial cell morphology using hydrogel grooves during ciliogenesis fails to induce ciliary alignment
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Isolation and characterization of porcine macrophages and their inflammatory and fusion responses in different stiffness environments

Evaluating the host immune response to biomaterials is an essential step in the development of medical devices and tissue engineering strategies.

Graphical abstract: Isolation and characterization of porcine macrophages and their inflammatory and fusion responses in different stiffness environments
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

A tripartite carbohydrate-binding module to functionalize cellulose nanocrystals

mSA-CBM3-AzF is a chimeric protein targeting cellulose nanocrystals (CNCs) with high affinity. It presents two additional domains providing a wide choice of chemical and biological molecules to functionalize CNCs.

Graphical abstract: A tripartite carbohydrate-binding module to functionalize cellulose nanocrystals
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Improved epithelial cell–cell adhesion using molecular mobility of supramolecular surfaces

The role of molecular mobility on polyrotaxane surfaces was investigated in epithelial cell–cell adhesion. The polyrotaxane surfaces with higher mobility induced cytoplasmic YAP localization, leading to stronger cell–cell adhesion.

Graphical abstract: Improved epithelial cell–cell adhesion using molecular mobility of supramolecular surfaces
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

The in vivo fate of tobacco mosaic virus nanoparticle theranostic agents modified by the addition of a polydopamine coat

The coating of tobacco mosaic virus (TMV) nanoparticles Gd-Cy5-TMV with polydopamine (PDA) increased protein corona formation and shortened plasma circulation, but minimized recognition by anti-TMV antibodies, and extended organ distribution/clearance.

Graphical abstract: The in vivo fate of tobacco mosaic virus nanoparticle theranostic agents modified by the addition of a polydopamine coat
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

A multifunctional green antibacterial rapid hemostasis composite wound dressing for wound healing

A green multifunctional wound dressing with low-cost that can accelerate wound healing in comparison to gauze.

Graphical abstract: A multifunctional green antibacterial rapid hemostasis composite wound dressing for wound healing
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Dual-sensitive dual-prodrug nanoparticles with light-controlled endo/lysosomal escape for synergistic photoactivated chemotherapy

The dual-sensitive dual-prodrug nanoparticles (DDNPs) with light-controlled drug-release on demand and endo/lysosomal escape for synergistic photoactivated chemotherapy.

Graphical abstract: Dual-sensitive dual-prodrug nanoparticles with light-controlled endo/lysosomal escape for synergistic photoactivated chemotherapy
From the themed collection: Biomaterials Science Recent HOT Articles
Open Access Paper

Interrogating cardiac muscle cell mechanobiology on stiffness gradient hydrogels

Mechanobiology of H9C2 cells and neonatal cardiomyocytes mapped using stiffness gradient hydrogels with a range of extracellular matrix coatings, revealing stiffness-driven trends in cell morphology, YAP and MRTF-A expression.

Graphical abstract: Interrogating cardiac muscle cell mechanobiology on stiffness gradient hydrogels
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

A facile method for high-throughput screening of drug-eluting coatings in droplet microarrays based on ultrasonic spray deposition

Droplet microarrays are fabricated for the high-throughput screening of drug-eluting coatings via ultrasonic spray deposition technique.

Graphical abstract: A facile method for high-throughput screening of drug-eluting coatings in droplet microarrays based on ultrasonic spray deposition
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Microneedle-mediated delivery of MIL-100(Fe) as a tumor microenvironment-responsive biodegradable nanoplatform for O2-evolving chemophototherapy

MIL-100(Fe) nanoparticles integrated microneedles were employed to codeliver the hydrophobic photosensitizer zinc phthalocyanine (ZnPc) and the chemotherapeutical drug doxorubicin hydrochlorate (Dox) (Z/D@MOF) for O2-evolving chemophototherapy.

Graphical abstract: Microneedle-mediated delivery of MIL-100(Fe) as a tumor microenvironment-responsive biodegradable nanoplatform for O2-evolving chemophototherapy
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

c-Met-targeted near-infrared fluorescent probe for real-time depiction and dissection of perineural invasion and lymph node metastasis lesions in pancreatic ductal adenocarcinoma xenograft models

c-Met-targeted near-infrared fluorescent probe has excellent targeting ability to pancreatic ductal adenocarcinoma (PDAC), and can be used for real-time detection of lymph node metastasis and perineural invasion lesions in PDAC xenograft models.

Graphical abstract: c-Met-targeted near-infrared fluorescent probe for real-time depiction and dissection of perineural invasion and lymph node metastasis lesions in pancreatic ductal adenocarcinoma xenograft models
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Pre-shear bioprinting of highly oriented porous hydrogel microfibers to construct anisotropic tissues

A pre-shear bioprinting strategy of oriented porous cell-laden hydrogel microfiber to construct anisotropic tissues is first proposed. Different cells encapsulated in the oriented microfibers exhibit oriented growth behaviors similar to that in vivo.

Graphical abstract: Pre-shear bioprinting of highly oriented porous hydrogel microfibers to construct anisotropic tissues
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Hydrophilic hindering and hydrophobic growing: a vesicle glycometabolism multi-drug combination therapeutic against Alzheimer's disease

Advanced drug vehicle exploitation and the sophisticated synergy mechanism revelation are two great difficulties in combination therapy.

Graphical abstract: Hydrophilic hindering and hydrophobic growing: a vesicle glycometabolism multi-drug combination therapeutic against Alzheimer's disease
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

A sulfonate-based polypeptide toward infection-resistant coatings

We developed a mono-component and sulfonate-based polypeptide coating with reversible on-demand bactericidal and antifouling properties.

Graphical abstract: A sulfonate-based polypeptide toward infection-resistant coatings
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

High-stability NIR-II fluorescence polymer synthesized by atom transfer radical polymerization for application in high-resolution NIR-II imaging

This article reports a high-stability NIR-II fluorescence polymer synthesized by atom transfer radical polymerization for application in high-resolution NIR-II imaging.

Graphical abstract: High-stability NIR-II fluorescence polymer synthesized by atom transfer radical polymerization for application in high-resolution NIR-II imaging
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Plasmonic enhanced enzyme activity by catalytic cascade induced mutual benefit tumor starvation/immune/photothermal therapy

Single tumor starvation therapy can activate other signaling pathways in tumor cells and easily induce tumor cell metastasis.

Graphical abstract: Plasmonic enhanced enzyme activity by catalytic cascade induced mutual benefit tumor starvation/immune/photothermal therapy
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Dual-sonosensitizer loaded phase-transition nanoparticles with tumor-targeting for synergistically enhanced sonodynamic therapy

Sonodynamic therapy (SDT) is a fast-growing therapy activated by using ultrasound to initiate a catalytic reaction of sensitizing agents and kill tumor cells through producing reactive oxygen species (ROS).

Graphical abstract: Dual-sonosensitizer loaded phase-transition nanoparticles with tumor-targeting for synergistically enhanced sonodynamic therapy
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Black phosphorus assisted polyionic micelles with efficient PTX loading for remotely controlled release and synergistic treatment of drug-resistant tumors

An illustration of black phosphorus (BP) assisted polyionic mPEG-PDMATC micelles with efficient PTX loading for remotely controlled release and synergistic treatment of drug-resistant tumors.

Graphical abstract: Black phosphorus assisted polyionic micelles with efficient PTX loading for remotely controlled release and synergistic treatment of drug-resistant tumors
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Vitamin E-facilitated carbon monoxide pro-drug nanomedicine for efficient light-responsive combination cancer therapy

A reliable approach is developed to formulate a targeted lipid-coated nanomedicine based on UCNP and co-loaded with CO-prodrug and vitamin E, which can convert NIR light to UV photon to release CO for synergistical cancer therapy with vitamin E.

Graphical abstract: Vitamin E-facilitated carbon monoxide pro-drug nanomedicine for efficient light-responsive combination cancer therapy
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

A pH-triggered fluorescence-switchable extracellular vesicle for tracing drug release and improving drug delivery

A pH-triggered fluorescence-switchable extracellular vesicle is developed by loading zwitterionic fluorescent carbon dots into macrophage cell-secreted vesicles, which enables to improve drug delivery and monitor drug release in real time.

Graphical abstract: A pH-triggered fluorescence-switchable extracellular vesicle for tracing drug release and improving drug delivery
From the themed collection: Biomaterials Science Recent HOT Articles
Paper

Synthesis of a zwitterionic N-Ser–Ser-C dimethacrylate cross-linker and evaluation in polyampholyte hydrogels

Polyampholyte hydrogels are attractive materials for tissue engineering scaffolds as they offer a wide variety of features including nonfouling, selective protein delivery, and tunable physical characteristics.

Graphical abstract: Synthesis of a zwitterionic N-Ser–Ser-C dimethacrylate cross-linker and evaluation in polyampholyte hydrogels
From the themed collection: Biomaterials Science Recent HOT Articles
58 items

About this collection

Welcome to our online rolling collection of the hottest work published in Biomaterials Science. Here we feature recent Biomaterials Science articles highlighted as HOT by the handling editor or our referees.

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