A visible-light photoredox-catalyzed four-component reaction for the construction of sulfone-containing quinoxalin-2(1H)-ones

Abstract

A simple and efficient visible-light photoredox-catalyzed four component tandem reaction of quinoxalin-2(1H)-ones, alkenes, aryldiazonium, and sodium metabisulfite has been developed at room temperature. Using rose bengal as a photocatalyst and under irradiation with 3 W blue LEDs, a number of sulfone-containing quinoxalin-2(1H)-ones could be conveniently synthesized in moderate to good yields. A possible radical reaction pathway involving photocatalysis is proposed.