Jump to main content
Jump to site search

Issue 20, 2015
Previous Article Next Article

Ultrafiltration modeling of non-ionic microgels

Author affiliations

Abstract

Membrane ultrafiltration (UF) is a pressure driven process allowing for the separation and enrichment of protein solutions and dispersions of nanosized microgel particles. The permeate flux and the near-membrane concentration-polarization (CP) layer in this process is determined by advective-diffusive dispersion transport and the interplay of applied and osmotic transmembrane pressure contributions. The UF performance is thus strongly dependent on the membrane properties, the hydrodynamic structure of the Brownian particles, their direct and hydrodynamic interactions, and the boundary conditions. We present a macroscopic description of cross-flow UF of non-ionic microgels modeled as solvent-permeable spheres. Our filtration model involves recently derived semi-analytic expressions for the concentration-dependent collective diffusion coefficient and viscosity of permeable particle dispersions [Riest et al., Soft Matter, 2015, 11, 2821]. These expressions have been well tested against computer simulation and experimental results. We analyze the CP layer properties and the permeate flux at different operating conditions and discuss various filtration process efficiency and cost indicators. Our results show that the proper specification of the concentration-dependent transport coefficients is important for reliable filtration process predictions. We also show that the solvent permeability of microgels is an essential ingredient to the UF modeling. The particle permeability lowers the particle concentration at the membrane surface, thus increasing the permeate flux.

Graphical abstract: Ultrafiltration modeling of non-ionic microgels

Back to tab navigation

Supplementary files

Publication details

The article was received on 23 Mar 2015, accepted on 23 Apr 2015 and first published on 23 Apr 2015


Article type: Paper
DOI: 10.1039/C5SM00678C
Author version
available:
Download author version (PDF)
Citation: Soft Matter, 2015,11, 4106-4122
  •   Request permissions

    Ultrafiltration modeling of non-ionic microgels

    R. Roa, E. K. Zholkovskiy and G. Nägele, Soft Matter, 2015, 11, 4106
    DOI: 10.1039/C5SM00678C

Search articles by author

Spotlight

Advertisements