Issue 32, 2015
From the journal:

Organic & Biomolecular Chemistry

Silver-catalyzed cascade reaction of tosylmethyl isocyanide (TosMIC) with propargylic alcohols to (E)-vinyl sulfones: dual roles of TosMIC†

Haniya Bounar,a   Zhenhua Liu,a   Lin Zhang,a   Xiaoxue Guan,a   Zonglian Yang,a   Peiqiu Liao,a   Xihe Bi*a  and  Xingqi Li*a  

* Corresponding authors

a Department of Chemistry, Northeast Normal University, 5268 Renmin Street, 130024 Changchun, China
E-mail: lixq653@nenu.edu.cn

Abstract

An unprecedented silver-catalyzed cascade reaction of tosylmethyl isocyanide (TosMIC) with propargylic alcohols for the efficient synthesis of (E)-vinyl sulfones has been developed where TosMIC plays a dual role as both the reactant in the allenylation of propargylic alcohols and the sulfonyl source.

Graphical abstract: Silver-catalyzed cascade reaction of tosylmethyl isocyanide (TosMIC) with propargylic alcohols to (E)-vinyl sulfones: dual roles of TosMIC

About
Cited by
Related
Download options Please wait...

Supplementary files

Article information

DOI
https://doi.org/10.1039/C5OB01129A
Article type
Paper
Submitted
05 Jun 2015
Accepted
08 Jul 2015
First published
09 Jul 2015

Org. Biomol. Chem., 2015,13, 8723-8728

Author version available

Download author version (PDF)

Permissions

Request permissions

Silver-catalyzed cascade reaction of tosylmethyl isocyanide (TosMIC) with propargylic alcohols to (E)-vinyl sulfones: dual roles of TosMIC

H. Bounar, Z. Liu, L. Zhang, X. Guan, Z. Yang, P. Liao, X. Bi and X. Li, Org. Biomol. Chem., 2015, 13, 8723 DOI: 10.1039/C5OB01129A

To request permission to reproduce material from this article, please go to the Copyright Clearance Center request page.

If you are an author contributing to an RSC publication, you do not need to request permission provided correct acknowledgement is given.

If you are the author of this article, you do not need to request permission to reproduce figures and diagrams provided correct acknowledgement is given. If you want to reproduce the whole article in a third-party publication (excluding your thesis/dissertation for which permission is not required) please go to the Copyright Clearance Center request page.

Read more about how to correctly acknowledge RSC content.

Social activity

Spotlight

Advertisements