Issue 2, 1986

A synthetic analogue of the carboxylate-binding pocket of vancomycin

Abstract

A synthetic analogue of the right-hand ring of vancomycin, the region in the antibiotic which contains the pocket for binding to the terminal carboxylate of D-Ala-D-Ala containing peptides, has been prepared and shows structural and spectroscopic similarity to the natural molecule.

Article information

Article type
Paper

J. Chem. Soc., Chem. Commun., 1986, 158-160

A synthetic analogue of the carboxylate-binding pocket of vancomycin

M. J. Mann, N. Pant and A. D. Hamilton, J. Chem. Soc., Chem. Commun., 1986, 158 DOI: 10.1039/C39860000158

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