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Issue 5, 1985
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Synthesis of L-quisqualic acid: a general method for enantio-efficient synthesis of β-aminoalanine derivatives

Abstract

A general method for the enantio-efficient synthesis of β-aminoalanine derivatives, which involves intramolecular transfer of the amino substituent from the αcarboxy to the β-carbon atom via an azetidinone is described with its application to an efficient synthesis of the neuroexcitatory quisqualic acid in an optically pure state.

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Article information


J. Chem. Soc., Chem. Commun., 1985, 256-257
Article type
Paper

Synthesis of L-quisqualic acid: a general method for enantio-efficient synthesis of β-aminoalanine derivatives

J. E. Baldwin, R. M. Adlington and D. J. Birch, J. Chem. Soc., Chem. Commun., 1985, 256
DOI: 10.1039/C39850000256

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