Synthesis of 9-hydroxy-HEOD, a major mammalian metabolite of HEOD (dieldrin)
Abstract
The first synthesis of a 9-hydroxylated derivative of HEOD (dieldrin) has been accomplished in three steps starting from hexachlorocyclopentadiene and 7-benzoyloxybicyclo[2,2,1]hepta-2,5-diene.