Dual role of bisulphite in the deamination of cytidine 5′-phosphate
Abstract
Kinetic studies have shown that bisulphite (or sulphite) ion actively participates in the deamination of 5,6-dihydrocytosine-6-sulphonate nucleotide, that is, an unusual enhancement of the overall rate of cytosine-deamination with bisulphite can be obtained by increasing the concentration of bisulphite in the reaction mixture.