Themed collection Chemistry for Medicine: Special Collection for RSC Advances
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Anti-bacterial surfaces: natural agents, mechanisms of action, and plasma surface modification
This article reviews antibacterial surface strategies based on reactive plasma chemistry, focusing on how plasma-assisted processing of natural antimicrobial agents can produce antifouling and antibacterial materials for biomedical devices.
RSC Adv., 2015,5, 48739-48759
https://doi.org/10.1039/C4RA17244B
Bioapplication of graphene oxide derivatives: drug/gene delivery, imaging, polymeric modification, toxicology, therapeutics and challenges
This review article summarizes the latest progress in research regarding bioapplications of graphene oxide derivatives and provides expert opinions on strategies for overcoming the current challenges.
RSC Adv., 2015,5, 42141-42161
https://doi.org/10.1039/C5RA04756K
Metal-free domino one-pot protocols for quinoline synthesis
Metal-free domino one-pot protocols for quinoline synthesis have been reviewed.
RSC Adv., 2015,5, 42020-42053
https://doi.org/10.1039/C5RA07798B
Recent advances in crosslinking chemistry of biomimetic poly(ethylene glycol) hydrogels
This article reviews recent advances in the crosslinking chemistries of biomimetic hydrogels prepared from PEG-based macromers.
RSC Adv., 2015,5, 39844-39853
https://doi.org/10.1039/C5RA05734E
Plasmon-enhanced light harvesting: applications in enhanced photocatalysis, photodynamic therapy and photovoltaics
This review article summarizes the recent progress on surface plasmon-enhanced light harvesting and its applications toward enhanced photocatalysis, photodynamic therapy, chemical transformations and photovoltaics.
RSC Adv., 2015,5, 29076-29097
https://doi.org/10.1039/C5RA01819F
Gallic acid: a versatile antioxidant with promising therapeutic and industrial applications
Oxidative stress, a result of an overproduction and accumulation of free radicals, is the leading cause of several degenerative diseases such as cancer, atherosclerosis, cardiovascular diseases, ageing and inflammatory diseases.
RSC Adv., 2015,5, 27540-27557
https://doi.org/10.1039/C5RA01911G
Modified biopolymer-dextrin based crosslinked hydrogels: application in controlled drug delivery
This review describes hydrogels and their classifications along with the synthesis and properties of biopolymer-dextrin based crosslinked hydrogels towards potential application in controlled drug delivery.
RSC Adv., 2015,5, 25014-25050
https://doi.org/10.1039/C4RA16103C
Toward point-of-care diagnostics with consumer electronic devices: the expanding role of nanoparticles
A review of the role that nanoparticles can play in point-of-care diagnostics that utilize consumer electronic devices such as cell phones and smartphones for readout, including an overview of important concepts and examples from the literature.
RSC Adv., 2015,5, 22256-22282
https://doi.org/10.1039/C4RA15036H
Fluorescent graphene quantum dots for biosensing and bioimaging
Graphene quantum dots with unique properties have great potential applications for biosensing and bioimaging.
RSC Adv., 2015,5, 19773-19789
https://doi.org/10.1039/C4RA17131D
Understanding cancer and the anticancer activities of naphthoquinones – a review
Naphthoquinone moieties are present in drugs such as doxorubicin which are used clinically to treat solid cancers.
RSC Adv., 2015,5, 20309-20338
https://doi.org/10.1039/C4RA13547D
Biological and pharmacological activities of amaryllidaceae alkaloids
This review discusses the recent developments on biological and pharmacological activities of amaryllidaceae alkaloids with IC50 or EC50 values since 2005, supporting the potential therapeutic possibilities for the use of these compounds.
RSC Adv., 2015,5, 16562-16574
https://doi.org/10.1039/C4RA14666B
Pyrrole: a resourceful small molecule in key medicinal hetero-aromatics
Pyrrole is widely known as a biologically active scaffold which possesses a diverse nature of activities.
RSC Adv., 2015,5, 15233-15266
https://doi.org/10.1039/C4RA15710A
Recent advances in the synthesis, characterization, and biomedical applications of ultrasmall thiolated silver nanoclusters
Recent advances in characterizing ultrasmall thiolated Ag nanoclusters, showing their optical and biological properties, and size, composition, and structure information.
RSC Adv., 2014,4, 60581-60596
https://doi.org/10.1039/C4RA12054J
Synthetic methodologies of achiral diarylmethanols, diaryl and triarylmethanes (TRAMs) and medicinal properties of diaryl and triarylmethanes-an overview
This review covers the synthesis of achiral diarylmethanols, diaryl and triarylmethanes and the bioactivities of diaryl and triarylmethanes during 1995 to 2013.
RSC Adv., 2014,4, 28317-28358
https://doi.org/10.1039/C4RA01341G
Bioimaging based on fluorescent carbon dots
Herein, we review the bioimaging application of three kinds of fluorescent carbon dots (CDs), namely, graphene quantum dots (GQDs), carbon nanodots (CNDs) and polymer dots (PDs).
RSC Adv., 2014,4, 27184-27200
https://doi.org/10.1039/C3RA47994C
Recent advances in the synthesis of quinolines: a review
This review article gives information about the recent advances in the synthesis of quinoline derivatives by various eco-friendly, green and clean protocols.
RSC Adv., 2014,4, 24463-24476
https://doi.org/10.1039/C4RA01814A
Mesoporous silica-based nanodevices for biological applications
This review highlights and addresses issues related to research on the development of mesoporous silica nanomaterials (MSNs) based nanodevices for biological applications.
RSC Adv., 2014,4, 18961-18980
https://doi.org/10.1039/C3RA47166G
Fabrication, modification, and biomedical applications of anodized TiO2 nanotube arrays
Recent research activities on the surface modification and biomedical applications of TiO2 NTAs are reviewed.
RSC Adv., 2014,4, 17300-17324
https://doi.org/10.1039/C4RA01458H
Polymeric micelles as drug delivery vehicles
Though much progress has been made in drug delivery systems, the design of a suitable carrier for the delivery of hydrophobic drugs is still a major challenge for researchers.
RSC Adv., 2014,4, 17028-17038
https://doi.org/10.1039/C3RA47370H
Nucleic acid therapeutics: basic concepts and recent developments
Nucleic acid based therapeutics comprising chemically modified oligonucleotides are the current focus of clinical research for the treatment of various diseases.
RSC Adv., 2014,4, 16618-16631
https://doi.org/10.1039/C3RA47841F
Mesoporous silica nanoparticles: importance of surface modifications and its role in drug delivery
This review considers the importance of surface modifications of mesoporous nanoparticles and their biological consequences.
RSC Adv., 2014,4, 14328-14334
https://doi.org/10.1039/C4RA00781F
Carbon-based quantum dots for fluorescence imaging of cells and tissues
On recent advances in the development of carbon-based quantum dots, carbon dots in particular, for fluorescence imaging of cells and tissues.
RSC Adv., 2014,4, 10791-10807
https://doi.org/10.1039/C3RA47683A
Curcumin, a promising anti-cancer therapeutic: a review of its chemical properties, bioactivity and approaches to cancer cell delivery
The chemical properties of curcumin as well as its proposed mechanism of action as an anti-cancer therapeutic are reviewed. Recent approaches to curcumin delivery are described.
RSC Adv., 2014,4, 10815-10829
https://doi.org/10.1039/C3RA46396F
Multi-functional fluorescent carbon dots with antibacterial and gene delivery properties
Dual-functionality carbon dots with both anti-microbial and gene transfection abilities were developed and their properties elaborated in this paper.
RSC Adv., 2015,5, 46817-46822
https://doi.org/10.1039/C5RA07968C
Alginate–peptide amphiphile core–shell microparticles as a targeted drug delivery system
We describe in this work the synthesis of microparticles with a doxorubicin drug conjugated alginate core and a shell of peptide amphiphile nanofibres functionalized for targeting the folate receptor.
RSC Adv., 2015,5, 8753-8756
https://doi.org/10.1039/C4RA16593D
Mesoporous silica nanoparticles enhance the cytotoxicity of curcumin
Curcumin encapsulated mesoporous silica nanoparticle (MSN) displaying higher cytotoxic for treatment in skin cancer cell line compared to pure curcumin.
RSC Adv., 2014,4, 709-712
https://doi.org/10.1039/C3RA44257H
PLA-based thermogel for the sustained delivery of chemotherapeutics in a mouse model of hepatocellular carcinoma
This work represents the first time that poly(PEG/PPG/PLA urethane) has been used for the delivery of drugs to tumours in vivo and the encouraging results point to the potential for further development of this thermogel platform for anti-cancer applications.
RSC Adv., 2016,6, 44506-44513
https://doi.org/10.1039/C6RA08022G
Safe and efficient membrane permeabilizing polymers based on PLLA for antibacterial applications
Highly active antibacterial poly(N,N-dimethylaminoethyl methacrylate)-block-poly(L-lactic acid)-block-poly(N,N-dimethylaminoethyl methacrylate) conjugated with poly(ethylene glycol) (D-PLLA-D@PEG) copolymers were synthesized.
RSC Adv., 2016,6, 28947-28955
https://doi.org/10.1039/C6RA04531F
Effects of the i-motif DNA loop on the fluorescence of silver nanoclusters
The loop sequences in i-motif DNA templates are well correlated with the fluorescence of the prepared Ag clusters.
RSC Adv., 2016,6, 22839-22844
https://doi.org/10.1039/C5RA22489F
Novel three-dimensional, conducting, biocompatible, porous, and elastic polyaniline-based scaffolds for regenerative therapies
Fabrication of two novel three-dimensional, conducting, biocompatible, porous, and elastic scaffolds composed of hyperbranched aliphatic polyesters, polyaniline, and poly(ε-caprolactone) for tissue engineering applications.
RSC Adv., 2016,6, 19437-19451
https://doi.org/10.1039/C6RA00643D
Design and development of a novel cellulose/γ-Fe2O3/Ag nanocomposite: a potential green catalyst and antibacterial agent
A new cellulose-based nanocomposite was synthesized, characterization and used for the synthesis of imidazoles and α-aminonitriles, and antibacterial property was investigated.
RSC Adv., 2016,6, 13657-13665
https://doi.org/10.1039/C5RA21350A
Osteoblastic cell responses and antibacterial efficacy of Cu/Zn co-substituted hydroxyapatite coatings on pure titanium using electrodeposition method
Effective physiological bone integration and absence of bacterial infection are essential for a successful orthopaedic or dental implant.
RSC Adv., 2015,5, 17076-17086
https://doi.org/10.1039/C4RA12118J
ZnO/Ag micro/nanospheres with enhanced photocatalytic and antibacterial properties synthesized by a novel continuous synthesis method
A continuous concentric impinging stream method was used for preparing ZnO/Ag MNSs, which possessed excellent photocatalytic and antibacterial activities.
RSC Adv., 2015,5, 612-620
https://doi.org/10.1039/C4RA12319K
Cyto and genotoxicities of graphene oxide and reduced graphene oxide sheets on spermatozoa
The interaction of graphene with spermatozoa resulted in trapping, oxidative stress, mitochondria damage, DNA damage and finally death of the spermatozoa.
RSC Adv., 2014,4, 27213-27223
https://doi.org/10.1039/C4RA01047G
Bifunctional TiO2/Ag3PO4/graphene composites with superior visible light photocatalytic performance and synergistic inactivation of bacteria
Schematic representation of the synthetic strategy for TiO2/Ag3PO4/GR composites.
RSC Adv., 2014,4, 18627-18636
https://doi.org/10.1039/C4RA01559B
Nanofibrous electroactive scaffolds from a chitosan-grafted-aniline tetramer by electrospinning for tissue engineering
Synthesis of chitosan–aniline tetramer and its electroactive nanofibrous scaffolds enhanced cell adhesion and proliferation of C2C12 myoblasts.
RSC Adv., 2014,4, 13652-13661
https://doi.org/10.1039/C4RA00083H
Aggregation-induced emission dye based luminescent silica nanoparticles: facile preparation, biocompatibility evaluation and cell imaging applications
Facile encapsulation of aggregation-induced emission dye into silica nanoparticles via a modified Stöber method was developed. Cell imaging applications of such luminescent silica nanoparticles were further investigated.
RSC Adv., 2014,4, 10060-10066
https://doi.org/10.1039/C3RA46076B
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Size-controlled silver nanoparticles synthesized over the range 5–100 nm using the same protocol and their antibacterial efficacy
Size-specific antibacterial activity of 5–100 nm silver nanoparticles synthesized using a novel co-reduction approach.
RSC Adv., 2014,4, 3974-3983
https://doi.org/10.1039/C3RA44507K
PVDF film tethered with RGD-click-poly(glycidyl methacrylate) brushes by combination of direct surface-initiated ATRP and click chemistry for improved cytocompatibility
PVDF film was functionalized by grafting of RGD-click-poly(glycidyl methacrylate) brushes using the combination of direct surface-initiated ATRP and alkyne-azide click reaction for improved cell adhesion and proliferation.
RSC Adv., 2014,4, 105-117
https://doi.org/10.1039/C3RA44789H