Themed collection Celebrating our 2018 prize and award winners
![](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/Ajax-GA-Loader.gif)
Fungal polyketide biosynthesis – a personal perspective
A personal summary of 40 years research in fungal polyketide biosynthesis is presented and developments in the field in the authors and other laboratories over that period are highlighted.
Nat. Prod. Rep., 2014,31, 1247-1252
https://doi.org/10.1039/C4NP00065J
Recent advances in the biosynthesis of unusual polyketide synthase substrates
Polyketides comprise a diverse class of natural products, with many important biological and pharmacological activities. Substrates functioning as starter units and extender units during their assembly significantly contribute to the chemical complexity exhibited by this class of natural products. This highlight provides an overview of the recent advances in understanding the diversity of these polyketide synthase (PKS) building blocks.
Nat. Prod. Rep., 2016,33, 150-161
https://doi.org/10.1039/C5NP00112A
From epoxomicin to carfilzomib : chemistry, biology, and medical outcomes
The selective proteasome inhibitor carfilzomib (Kyprolis™), derived from the potent antitumor natural product epoxomicin, has been recently approved by the FDA for multiple myeloma. Here we present an account of the journey that began with the discovery of epoxomicin and ended with the successful development of a life-changing drug.
Nat. Prod. Rep., 2013,30, 600-604
https://doi.org/10.1039/C3NP20126K
Solution, surface, and single molecule platforms for the study of DNA-mediated charge transport
The parameters governing the rate, yield, and mechanism of DNA-mediated charge transport are explored in a variety of experimental systems.
Phys. Chem. Chem. Phys., 2012,14, 13754-13771
https://doi.org/10.1039/C2CP41602F
Green chemistry teaching in higher education: a review of effective practices
Chem. Educ. Res. Pract., 2012,13, 69-79
https://doi.org/10.1039/C1RP90065J
Exploring the cellular accumulation of metal complexes
The biological application of metal complexes requires an understanding of cellular uptake; here we describe a variety of techniques used to gain insight into the mechanism of uptake, localization, and efflux.
Dalton Trans., 2010,39, 1159-1170
https://doi.org/10.1039/B922209J
Education: a microfluidic platform for university-level analytical chemistry laboratories
We demonstrate continuous flow acid–base titration reactions as an educational microfluidic platform for undergraduate and graduate analytical chemistry courses.
Lab Chip, 2012,12, 696-701
https://doi.org/10.1039/C2LC20951A
Acetylene hydrochlorination using Au/carbon: a journey towards single site catalysis
The replacement of mercuric chloride in the production of vinyl chloride monomer, a precursor to PVC, would greatly reduce the environmental impact of this large scale industrial process.
Chem. Commun., 2017,53, 11733-11746
https://doi.org/10.1039/C7CC05986H
Supramolecular assembly /reassembly processes: molecular motors and dynamers operating at surfaces
Supramolecular engineering comprises the design, synthesis and self-assembly of well-defined molecular modules into dynamic architectures. Scanning tunneling microscopy studies were used to trigger, with a sub-nanometre resolution, the formation of responsive architectures with controlled geometries and properties.
Nanoscale, 2011,3, 1397-1410
https://doi.org/10.1039/C0NR00914H
The intrinsic nanofibrillar morphology of polyaniline
Nanofibrillar morphology is found to be intrinsic to polyaniline chemically synthesized in water. In conventional synthesis (left), the product that readily precipitates out of the solution is a mixture of irregularly-shaped, micron-sized particulates and nanofibers. In interfacial polymerization (middle) and rapidly-mixed reactions (right), the products are pure nanofibers that disperse very well in water.
Chem. Commun., 2006, 367-376
https://doi.org/10.1039/B510956F
Scanning probe microscopies beyond imaging
Scanning probe microscopies offer access to physico-chemical properties of complex molecular adsorbates on the nanoscale. Beyond imaging, e.g. nanomanipulations, the nanomechanics and electronics of molecular objects can be studied.
J. Mater. Chem., 2004,14, 1353-1366
https://doi.org/10.1039/B314626J
Systems chemistry
A series of exciting phenomena that can occur in supramolecular systems away from equilibrium are reviewed.
Chem. Soc. Rev., 2017,46, 2543-2554
https://doi.org/10.1039/C7CS00117G
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
Block copolymer self-assembly for nanophotonics
From tunable reflectors to 3D metamaterials, the self-assembly of block copolymers is advancing nanostructures for photonic applications.
Chem. Soc. Rev., 2015,44, 5076-5091
https://doi.org/10.1039/C4CS00517A
The marine actinomycete genus Salinispora: a model organism for secondary metabolite discovery
This review covers the discovery of the marine actinomycete genus Salinispora and its development as a model for natural products research.
Nat. Prod. Rep., 2015,32, 738-751
https://doi.org/10.1039/C4NP00167B
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
Selection of boron reagents for Suzuki–Miyaura coupling
This review analyses the general physical and chemical properties of the seven main classes of boron reagent that have been employed for SM coupling.
Chem. Soc. Rev., 2014,43, 412-443
https://doi.org/10.1039/C3CS60197H
Chemical analysis in saliva and the search for salivary biomarkers – a tutorial review
A review of the uses of saliva biomarkers, detection methods and requirements for new biomarkers.
Analyst, 2018,143, 81-99
https://doi.org/10.1039/C7AN01571B
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
Is food allergen analysis flawed? Health and supply chain risks and a proposed framework to address urgent analytical needs
Food allergy is an increasing problem. If we fail to realise the promise of current risk assessment and risk management of food allergens through lack of ability to measure them reproducibly and with traceability to an international unit of measurement, the analytical community will have failed a significant societal challenge.
Analyst, 2016,141, 24-35
https://doi.org/10.1039/C5AN01457C
Using an environmentally-relevant panel of Gram-negative bacteria to assess the toxicity of polyallylamine hydrochloride-wrapped gold nanoparticles
We aim to establish the effect of bacterial diversity in assessing nanotoxicity.
Environ. Sci.: Nano, 2018,5, 279-288
https://doi.org/10.1039/C7EN00832E
Design and construction of artificial photoresponsive protocells capable of converting day light to chemical energy
Design and construction of artificial photoresponsive protocells based on the encapsulation and activation of metallized peptide/porphyrin self-assembled nanofilaments within silica-nanoparticle-stabilized colloidosomes.
J. Mater. Chem. A, 2017,5, 24612-24616
https://doi.org/10.1039/C7TA08999F
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
Polymer colour converter with very high modulation bandwidth for visible light communications
We report the synthesis, photophysics and application of a novel semiconducting polymer as a colour converter for high speed visible light communication.
J. Mater. Chem. C, 2017,5, 8916-8920
https://doi.org/10.1039/C7TC03787B
Oxygenophilic ionic liquids promote the oxygen reduction reaction in Pt-free carbon electrocatalysts
We propose a novel idea to improve the surface properties of carbon-based Pt-free electrocatalysts in Polymer Electrolyte Membrane Fuel Cells (PEMFCs) and Alkaline Fuel Cells (AFCs).
Mater. Horiz., 2017,4, 895-899
https://doi.org/10.1039/C7MH00298J
Amino acid functionalisation using the 2-phosphaethynolate anion. A facile route to (phosphanyl)carbonyl-amino acids
We describe the reactivity of the 2-phosphaethynolate anion (PCO−) towards enantiomerically pure α-amino acids (AAs) resulting in the formation of novel salts of phosphinecarboxamides bearing chiral functionalities.
Chem. Commun., 2017,53, 7092-7095
https://doi.org/10.1039/C7CC01285C
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
Encapsulation of a {Cu16} cluster containing four [Cu4O4] cubanes within an isopolyoxometalate {W44} cluster
We report a {Cu16} embedded within a {W44} cluster containing four cubane-like [Cu4O4] units within an isopolyoxotungstate (isoPOT) in a {Na4Cu4[(H2W11O38) (CH3COO)(OH)3]}4·88H2O (1) and a polyanion Cu-linked {W11} chain Na6Cu2[(H2W11O38)(CH3COO)(OH)]·26H2O (2).
Chem. Commun., 2017,53, 7076-7079
https://doi.org/10.1039/C7CC03544F
N-Heterocyclic carbene-stabilised arsinidene (AsH)
N-Heterocyclic carbene adducts of the parent arsinidene (AsH) were prepared by two different synthetic routes, either by reaction of As(SiMe3)3 with 2,2-difluoroimidazolines followed by desilylation or by reaction of [Na(dioxane)3.31][AsCO] with imidazolium chlorides.
Chem. Commun., 2017,53, 6069-6072
https://doi.org/10.1039/C7CC02628E
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
6-exo-trig Michael addition-lactonizations for catalytic enantioselective chromenone synthesis
The catalytic enantioselective 6-exo-trig Michael addition-lactonization of enone-acid substrates to form cis-chromenones with high diastereo- and enantiocontrol was developed using the commercially available isothiourea tetramisole.
Chem. Commun., 2017,53, 2555-2558
https://doi.org/10.1039/C6CC10178J
Cyclotrimerisation of isocyanates catalysed by low-coordinate Mn(II) and Fe(II) m-terphenyl complexes
Isocyanurates can be synthesised through the cyclotrimerisation of primary isocyanates catalysed by low-coordinate manganese(II) and iron(II) m-terphenyl complexes under mild conditions.
Chem. Commun., 2017,53, 937-940
https://doi.org/10.1039/C6CC07243G
Visible-light-mediated generation of nitrile oxides for the photoredox synthesis of isoxazolines and isoxazoles
Visible-light photoredox catalysis enables the synthesis of biologically relevant isoxazolines and isoxazoles from hydroxyimino acids.
Chem. Commun., 2016,52, 12302-12305
https://doi.org/10.1039/C6CC06029C
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
A new perspective in bio-refining: levoglucosenone and cleaner lignin from waste biorefinery hydrolysis lignin by selective conversion of residual saccharides
The sustainability of biorefineries can be improved through levoglucosenone production from residual sugars in waste lignin.
Energy Environ. Sci., 2016,9, 2571-2574
https://doi.org/10.1039/C6EE01352J
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
Synchronous intramolecular cycloadditions of the polyene macrolactam polyketide heronamide C
Two spontaneous intramolecular cycloadditions lead to the biosynthetic congeners heronamide A and B.
Chem. Commun., 2016,52, 6383-6386
https://doi.org/10.1039/C6CC01930G
Hollow mesoporous raspberry-like colloids with removable caps as photoresponsive nanocontainers
The fabrication, characterisation and controlled cargo release of hollow mesoporous raspberry-like colloids (HMRCs), which are assembled by utilising host–guest complexation of cucurbit[8]uril (CB[8]) are described.
Nanoscale, 2016,8, 7840-7844
https://doi.org/10.1039/C6NR01016D
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
In vitro gene expression within membrane-free coacervate protocells
Cell-free gene expression of a fluorescent protein (mCherry) is demonstrated within the molecularly crowded matrix of a polysaccharide/polypeptide coacervate.
Chem. Commun., 2015,51, 11429-11432
https://doi.org/10.1039/C5CC04220H
Synthesis and indole coupling reactions of azetidine and oxetane sulfinate salts
Azetidine and oxetane sulfinate salts are easily prepared from commercially available 3-iodoheterocycle precursors in a three-step sequence.
Chem. Commun., 2015,51, 5914-5916
https://doi.org/10.1039/C5CC00975H
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
The first near-linear bis(amide) f-block complex: a blueprint for a high temperature single molecule magnet
An unprecedented near-linear bis(amide) f-element complex has been prepared by utilizing bulky silylamide ligands. This Sm(II) complex is a blueprint for the next generation of single molecule magnets, where predictions for the Dy(III) analogue suggest they could operate above 77 K.
Chem. Commun., 2015,51, 101-103
https://doi.org/10.1039/C4CC08312A
Rescuing DNA repair activity by rewiring the H-atom transfer pathway in the radical SAM enzyme, spore photoproduct lyase
Engineering the active site of the spore photoproduct lyase, a radical SAM enzyme involved in DNA repair, proves that it is possible to rewire the H-atom transfer pathway in a radical SAM enzyme.
Chem. Commun., 2014,50, 14201-14204
https://doi.org/10.1039/C4CC05158K
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
Synthesis and kinetic resolution of N-Boc-2-arylpiperidines
An efficient kinetic resolution of 2-arylpiperidines was developed using a chiral base.
Chem. Commun., 2014,50, 9910-9913
https://doi.org/10.1039/C4CC04576A
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
A microstereolithography resin based on thiol-ene chemistry: towards biocompatible 3D extracellular constructs for tissue engineering
A new class of degradable aliphatic poly(carbonate) resins for use in microstereolithographic process is described.
Biomater. Sci., 2014,2, 472-475
https://doi.org/10.1039/C3BM60290G
Covalent ladder formation becomes kinetically trapped beyond four rungs
Scrambling experiments suggest that oligomers cross-linked by four imine bonds are kinetically trapped, limiting the synthesis of covalent ladders with five or more rungs.
Chem. Commun., 2011,47, 5028-5030
https://doi.org/10.1039/C1CC11242B
Pronounced effects of substituents on the iridium-catalyzed borylation of aryl C–H bonds
Iridium trisboryl complexes containing bisphosphine and bipyridine ligands and pinacolate and catecholate substituents are reported.
Chem. Commun., 2009, 5603-5605
https://doi.org/10.1039/B913949D
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
Direct and indirect hyperpolarisation of amines using parahydrogen
Para-hydrogen achieves the hyperpolarisation of amines via SABRE.
Chem. Sci., 2018,9, 3677-3684
https://doi.org/10.1039/C8SC00526E
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
ZnSe quantum dots modified with a Ni(cyclam) catalyst for efficient visible-light driven CO2 reduction in water
A robust precious metal-free photocatalyst system comprised of ligand-free ZnSe quantum dots and a phosphonic acid-functionalised Ni(cyclam) catalyst achieves efficient reduction of aqueous CO2 to CO.
Chem. Sci., 2018,9, 2501-2509
https://doi.org/10.1039/C7SC04429A
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
A practical, organic-mediated, hybrid electrolyser that decouples hydrogen production at high current densities
A hybrid electrolyser utilising anthraquinone disulfonic acid allows H2 and O2 production to be decoupled at current densities of up to 3.71 A cm−2, and provides an inherently safer and more flexible approach to water splitting.
Chem. Sci., 2018,9, 1621-1626
https://doi.org/10.1039/C7SC05388F
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
Sensing iron availability via the fragile [4Fe–4S] cluster of the bacterial transcriptional repressor RirA
The global iron regulator RirA controls transcription of iron metabolism genes via the binding of a fragile [4Fe–4S] cluster.
Chem. Sci., 2017,8, 8451-8463
https://doi.org/10.1039/C7SC02801F
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
Evolved polymerases facilitate selection of fully 2′-OMe-modified aptamers
Evolved DNA polymerases are used in selections with fully 2′-OMe modified libraries to identify aptamers with high affinity for HNE.
Chem. Sci., 2017,8, 8179-8182
https://doi.org/10.1039/C7SC03747C
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
Understanding single enzyme activity via the nano-impact technique
The electrochemical detection and characterisation of individual enzymes via the nano-impact technique is predicted.
Chem. Sci., 2017,8, 6423-6432
https://doi.org/10.1039/C7SC02084H
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
Metathesis of a UV imido complex: a route to a terminal UV sulfide
The metathesis reaction of a UV imido complex supported by sterically demanding tris(tert-butoxy)siloxide ligands with CS2 afforded a terminal UV thiocarbonate but metathesis with H2S afforded the first example of a terminal UV sulfide.
Chem. Sci., 2017,8, 5319-5328
https://doi.org/10.1039/C7SC01111C
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
[MIII2MII3]n+ trigonal bipyramidal cages based on diamagnetic and paramagnetic metalloligands
A family of [MIII2MII3]n+ trigonal bipyramidal cages are characterised in the solution and solid state.
Chem. Sci., 2017,8, 5526-5535
https://doi.org/10.1039/C7SC00487G
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
A well-defined NHC–Ir(III) catalyst for the silylation of aromatic C–H bonds: substrate survey and mechanistic insights
A well-defined NHC-Ir(III) catalyst provides access to a wide range of aryl- and heteroarylsilanes by intermolecular dehydrogenative C–H bond silylation.
Chem. Sci., 2017,8, 4811-4822
https://doi.org/10.1039/C6SC04899D
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
A 2-aza-Cope reactivity-based platform for ratiometric fluorescence imaging of formaldehyde in living cells
We present the first ratiometric fluorescent probes for formaldehyde, a major reactive species in biology, operating in the visible region.
Chem. Sci., 2017,8, 4073-4081
https://doi.org/10.1039/C7SC00748E
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
Mild, visible light-mediated decarboxylation of aryl carboxylic acids to access aryl radicals
Herein we present the first example of aryl radical formation via the visible light-mediated decarboxylation of aryl carboxylic acids using photoredox catalysis.
Chem. Sci., 2017,8, 3618-3622
https://doi.org/10.1039/C6SC05533H
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
Manganese-catalyzed allylation via sequential C–H and C–C/C–Het bond activation
Manganese-catalyzed sequential C–H and C–C/C–Het bond activation to synthesize allylic alcohols, allylated arenes, functionalized cyclopentenes and skipped dienes is reported.
Chem. Sci., 2017,8, 3379-3383
https://doi.org/10.1039/C7SC00230K
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
Formicamycins, antibacterial polyketides produced by Streptomyces formicae isolated from African Tetraponera plant-ants
Ant pharming: antibacterial polyketides from plant-ant associated bacteria.
Chem. Sci., 2017,8, 3218-3227
https://doi.org/10.1039/C6SC04265A
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
The development and mechanistic investigation of a palladium-catalyzed 1,3-arylfluorination of chromenes
A mild palladium-catalyzed ligand-controlled regioselective 1,3-arylfluorination of 2[H]-chromenes has been developed.
Chem. Sci., 2017,8, 2890-2897
https://doi.org/10.1039/C6SC05102B
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
Reduction chemistry of neptunium cyclopentadienide complexes: from structure to understanding
Structural investigation on neptunium cyclopentadienyl organometallic complexes in the formal oxidation states II, III, and IV: similarities and differences between Np and U.
Chem. Sci., 2017,8, 2553-2561
https://doi.org/10.1039/C7SC00034K
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
A tendril perversion in a helical oligomer: trapping and characterizing a mobile screw-sense reversal
Inducing opposite screw senses at the two ends of a helix traps a helix reversal, allowing it to be characterised spectroscopically.
Chem. Sci., 2017,8, 3007-3018
https://doi.org/10.1039/C6SC05474A
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
Inner-sphere vs. outer-sphere reduction of uranyl supported by a redox-active, donor-expanded dipyrrin
The uranyl(VI) complex UO2Cl(L) of the redox-active diimino-dipyrrin anion, L− is reported and its reactions with inner- and outer-sphere reductants studied.
Chem. Sci., 2017,8, 108-116
https://doi.org/10.1039/C6SC02912D
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
Mechanistic studies on the addition of hydrogen to iridaepoxide complexes with subsequent elimination of water
Iridium complexes of the PCsp2P ligand in which the donors are linked by 2,3-benzo[b]thiophene groups engage in the cooperative activation of N2O and the resulting iridaepoxides can be treated with dihydrogen to effect elimination of water and regeneration of the starting iridium complex.
Chem. Sci., 2016,7, 921-931
https://doi.org/10.1039/C5SC03575A
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
Pd-η3-C6H9 complexes of the Trost modular ligand: high nuclearity columnar aggregation controlled by concentration, solvent and counterion
Pd-η3-C6H9 cations bearing the Trost ligand (2) undergo two-stage oligomerisation-aggregation to form high nuclearity aggregates (up to 56 Pd centres), with aggregation strongly modulated by concentration, solvent and counter-anion.
Chem. Sci., 2015,6, 5793-5801
https://doi.org/10.1039/C5SC01181G
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
Flaws in foldamers: conformational uniformity and signal decay in achiral helical peptide oligomers
The conformational influence of a single stereogenic centre in an otherwise achiral oligomer behaves as a signal that decays with distance.
Chem. Sci., 2015,6, 2313-2322
https://doi.org/10.1039/C4SC03944K
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
Enantioselective α-amination enabled by a BINAM-derived phase-transfer catalyst
The enantioselective amination of carbonyl derivatives is achieved via phase-transfer of aryldiazonium salts by BINAM-derived phosphoric acids.
Chem. Sci., 2015,6, 170-173
https://doi.org/10.1039/C4SC02494J
Catenanes from catenanes: quantitative assessment of cooperativity in dynamic combinatorial catenation
A series of dynamic combinatorial [2] and [3]catenanes have been prepared. Formation of the [3]catenanes occurs with positive or negative cooperativity, depending on the cyclodextrin homologue. Systems level analysis allows cooperativity to be quantified and MD simulations reveal that cooperativity derives from the extents to which hydrophobic surface area is exposed to the aqueous surroundings.
Chem. Sci., 2014,5, 4968-4974
https://doi.org/10.1039/C4SC01998A
Iridium-catalyzed diborylation of benzylic C–H bonds directed by a hydrosilyl group: synthesis of 1,1-benzyldiboronate esters
We describe the regioselective diborylation of 2-methyl hydrosilylarenes by the combination of [Ir(COD)OMe]2 as metal precursor and 4,4′-di-tert-butyl-2,2′-bipyridine to form diborylbenzylic compounds.
Chem. Sci., 2014,5, 694-698
https://doi.org/10.1039/C3SC52824C
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
Biosynthesis of thiomarinol A and related metabolites of Pseudoalteromonas sp. SANK 73390
Biosynthesis of the PKS-FAS-NRPS hybrid antibiotic thiomarinol A was investigated using feeding studies in wild type and mutant strains of the marine bacterium Pseudoalteromonas.
Chem. Sci., 2014,5, 397-402
https://doi.org/10.1039/C3SC52281D
Decamethylscandocinium-hydrido-(perfluorophenyl)borate: fixation and tandem tris(perfluorophenyl)borane catalysed deoxygenative hydrosilation of carbon dioxide
Facile reduction of CO2 by a decamethylscandocene hydridoborate contact ion pair, followed by B(C6F5)3 catalysed hydrosilation constitutes a highly active tandem catalyst system for the hydrosilation of CO2 to CH4.
Chem. Sci., 2013,4, 2152-2162
https://doi.org/10.1039/C3SC50145K
Photoelectron spectroscopy of solvated electrons in alcohol and acetonitrile microjets
Solvated electrons are generated in methanol, ethanol, and acetonitrile liquid microjets. Their binding energies are studied by photoelectron spectroscopy and compared to solvent cluster findings.
Chem. Sci., 2013,4, 1633-1639
https://doi.org/10.1039/C3SC22063J
Salt metathesis routes to homoleptic near-linear Mg(II) and Ca(II) bulky bis(silyl)amide complexes
A series of bulky bis(silyl)amide ligands have been utilised to stabilise rare examples of formally 2-coordinate linear or near-linear Mg and Ca complexes.
Dalton Trans., 2018,47, 12526-12533
https://doi.org/10.1039/C8DT00802G
![Open Access](https://www.rsc-cdn.org/pubs-core/2022.0.148/content/NewImages/open-access-icon-orange.png)
Order in disorder: solution and solid-state studies of [MIII2MII5] wheels (MIII = Cr, Al; MII = Ni, Zn)
Heterometallic species with Anderson-like structures are characterised by single-crystal X-ray diffraction, solution- and solid-state NMR spectroscopy, ESI mass spectrometry and SQUID magnetometry.
Dalton Trans., 2018,47, 11834-11842
https://doi.org/10.1039/C8DT00685G
Investigation of ternary metal dodecaborides (M1M2M3)B12 (M1, M2 and M3 = Zr, Y, Hf and Gd)
Optical images of the surface patterns formed by hexaboride (MB6) and dodecaboride (MB12) phases.
Dalton Trans., 2018,47, 6683-6691
https://doi.org/10.1039/C8DT00563J
Multimodal LA-ICP-MS and nanoSIMS imaging enables copper mapping within photoreceptor megamitochondria in a zebrafish model of Menkes disease
Coregistering quantitative high-resolution metal imaging with fluorescence imaging identifies copper accumulation in megamitochondria within intact neuroretinal slices.
Metallomics, 2018,10, 474-485
https://doi.org/10.1039/C7MT00349H
Unexpected insights into antibacterial activity of zinc oxide nanoparticles against methicillin resistant Staphylococcus aureus (MRSA)
Zinc oxide nanoparticles cause marked up-regulation of pyrimidine biosynthesis and sugar metabolism but consistent down-regulation of amino acid synthesis in MRSA, suggesting a previously unrecognized mechanism of action.
Nanoscale, 2018,10, 4927-4939
https://doi.org/10.1039/C7NR08499D
Frustrated Lewis pairs incorporating the bifunctional Lewis acid 1,1′-fc{B(C6F5)2}2: reactivity towards small molecules
Applications of the bifunctional Lewis acid 1,1′-fc{B(C6F5)2}2 in FLP chemistry are described, including reactions towards H2O, NH3, CO2 and cyclohexylisocyanate.
Dalton Trans., 2018,47, 1588-1598
https://doi.org/10.1039/C7DT04136E
About this collection
In celebration of the 2018 Royal Society of Chemistry prizes and awards, we have collected together some of the exciting research recently published by the winners. This collection showcases articles authored by the winners from across the Royal Society of Chemistry’s journals portfolio – these articles are free to access until 1st August 2018.
Why not also have a look at last year’s collection of articles by our 2017 winners here.