Themed collection Soft Matter Open Access Spotlight


Complex remodeling of biomembranes and vesicles by condensate droplets
Condensate droplets arise from phase separation into two liquid phases α (white) and β (green). Vesicle membranes exposed to such droplets are divided up into two membrane segments (red and purple), which can form membrane nanotubes.
Soft Matter, 2025, Advance Article
https://doi.org/10.1039/D5SM00585J

Materials science underpinnings of micro and nanoplastics
In this perspective, we discuss the fundamental mechanisms and the length scales responsible for the formation of micro- and nanoplastics (MNPLs), MNPL size, shape, and morphologies, their metrology, and open questions in the field.
Soft Matter, 2025,21, 6023-6033
https://doi.org/10.1039/D5SM00297D

Morphogenesis of confined biofilms: how mechanical interactions determine cellular patterning and global geometry
Bacterial biofilms that grow under confinement can mechanically interact with their environment to generate various global geometries and forms of cellular patterning.
Soft Matter, 2025,21, 1436-1450
https://doi.org/10.1039/D4SM01180E

Co-assembly of nanometer- and submicrometer-sized colloidal particles into multi-component ordered superstructures
The co-assembly of nanometer- and submicrometer-sized colloidal particles can result in multi-component superstructures with unique properties.
Soft Matter, 2025,21, 5583-5654
https://doi.org/10.1039/D5SM00247H

(Sub-)microscale patterning via microcontact printing (μCP): recent advances, applications and future perspectives
Microcontact printing (μCP) is a versatile and low-cost technique for surface patterning, allowing for the fabrication of intricate designs with relative ease.
Soft Matter, 2025, Advance Article
https://doi.org/10.1039/D5SM00355E

Curvature-sensing and generation by membrane proteins: a review
We review the recent theoretical and simulation studies on interactions between curvature-inducing proteins and membranes.
Soft Matter, 2025,21, 3922-3940
https://doi.org/10.1039/D5SM00101C

Polyvinyl alcohol-based polarizers for new displays: molecules, processing and properties
This review clarifies the structure–process–property relationship in PVA-based polarizers.
Soft Matter, 2025,21, 3148-3167
https://doi.org/10.1039/D4SM01530D

Recent advances in nanoprecipitation: from mechanistic insights to applications in nanomaterial synthesis
Nanoprecipitation is a versatile, low-energy technique for synthesizing nanomaterials through phase separation, enabling precise tuning of nanomaterial properties.
Soft Matter, 2025,21, 2759-2781
https://doi.org/10.1039/D5SM00006H

Ion-conducting polymer thin films via chemical vapor deposition polymerization
Ion-conducting polymers (ICPs) are gaining interest in various scientific and technological fields. This review highlights advancements in ICP thin films using chemical vapor deposition (CVD) and addresses challenges of traditional methods.
Soft Matter, 2025,21, 1813-1834
https://doi.org/10.1039/D4SM01346H

Network design for soft materials: addressing elasticity and fracture resistance challenges
This review explores network designs that address the trade-off between toughness and elasticity, offering strategies to develop materials with both high fracture resistance and low hysteresis for advanced applications.
Soft Matter, 2025,21, 1603-1623
https://doi.org/10.1039/D4SM01430H

Liquid slide electrification: advances and open questions
This review is about drops of a liquid with high dielectric permittivity that slide over a solid surface with high electrical resistivity.
Soft Matter, 2025,21, 1251-1262
https://doi.org/10.1039/D4SM01289E

Optical coherence tomography in soft matter
Optical coherence tomography (OCT) has been introduced through detailed tutorials, accompanied by a code package, as a powerful technique suitable for versatile investigations in fluid mechanics and soft matter physics.
Soft Matter, 2025,21, 3425-3442
https://doi.org/10.1039/D4SM01537A

Droplet spreading in a wedge: a route to fluid rheology for power-law liquids
The spreading of a drop in a wedge shows anomalous diffusion scaling, with the diffusion exponent directly linked to the fluid's rheological properties.
Soft Matter, 2025, Advance Article
https://doi.org/10.1039/D5SM00286A

Free energy modelling of a spherical nanoparticle at an oil/water interface
In models of Pickering emulsion stabilisation, it is assumed that Young’s equation defines the angle of a solid particle at the oil/water interface. Here, we consider the implications for stability when the particle is displaced by an external force.
Soft Matter, 2025,21, 5188-5193
https://doi.org/10.1039/D5SM00501A

Microrheology of gel-forming airway mucins isolated from porcine trachea
A method to extract gel-forming mucins from pig trachea is developed. These airway mucins form viscous gels resembling human airway mucus, making them a useful model for lung disease research.
Soft Matter, 2025,21, 4999-5004
https://doi.org/10.1039/D4SM01343C

Transport of partially active polymers in chemical gradients
Connecting active and passive monomers to form partially active polymers can lead to directed transport towards regions of high or low chemical concentration.
Soft Matter, 2025,21, 1835-1840
https://doi.org/10.1039/D4SM01357C

Errors matter when measuring Poisson's ratio of nearly incompressible elastomers
Multiple pathways exist for measuring Poisson’s ratio. Not all methods are appropriate for nearly incompressible materials.
Soft Matter, 2025, Advance Article
https://doi.org/10.1039/D5SM00535C

Photodegradation-driven microparticle release from commercial plastic water bottles
Microparticles are released into water when plastic bottles undergo photodegradation under sunlight.
Soft Matter, 2025, Advance Article
https://doi.org/10.1039/D5SM00469A

Co-motion of catalytic tubes and host droplets on superhydrophobic surfaces
Catalytic chemical garden tubes self-propel in H2O2 droplets where spatial confinement induces spinning or rotation. Internal bubble growth enlarges the drop and triggers translational jumps upon bursting.
Soft Matter, 2025,21, 6299-6306
https://doi.org/10.1039/D5SM00576K

Investigating polymer infiltration kinetics in nanoporous metal scaffolds using UV-vis spectroscopy
Polymer infiltration into nanoporous gold dynamically tunes the optical response of the nanocomposite. UV-vis spectroscopy and DDA show red-shifting of plasmon resonance as infiltration progresses, enabling in situ tracking of polymer dynamics.
Soft Matter, 2025,21, 6274-6286
https://doi.org/10.1039/D5SM00423C

Dispersions of weakly charged thermoresponsive microgels at high densities
Weakly charged, thermoresponsive microgels are studied in the presence and absence of salt focusing on the phase behavior in dense packings. Temperature-dependent phase diagrams for both states are derived.
Soft Matter, 2025,21, 6220-6233
https://doi.org/10.1039/D5SM00464K

Janssen effect in submerged granular columns
The pressure saturation with depth is studied in submerged columns of grains denser and lighter than water. The total force acting on the particles is redirected towards the container walls, resulting in a buoyancy-driven Janssen effect.
Soft Matter, 2025,21, 6234-6242
https://doi.org/10.1039/D5SM00523J

Thermodynamic investigation of renewable block copolymers based on poly(lactic acid) and poly(ethylene azelate)
Molecular mobility in renewable PEAz-b-PLA block copolymers.
Soft Matter, 2025, Advance Article
https://doi.org/10.1039/D5SM00646E

Magnetically induced drug release from niosome-based nanocarriers loaded with doxorubicin
Doxorubicin (DOX) was coloaded with magnetic nanoparticles (MNPs) into the core of a niosome (NS). On the application of a magnetic field the MNPs produced heat and released the DOX.
Soft Matter, 2025,21, 6197-6206
https://doi.org/10.1039/D5SM00411J

Low-profile folding mechanism for multi-DoF feedback control
An ultra-thin, modular pneumatic system with integrated sensing and transmission enables precise control of folding structures, offering a scalable solution for reconfigurable robots with complex geometries.
Soft Matter, 2025,21, 6186-6196
https://doi.org/10.1039/D5SM00143A

Run-and-tumble dynamics of active giant vesicles
Janus lipid vesicles exhibit run-and-tumble dynamics under AC fields, driven by membrane fluidity and lipid phase reconfiguration that transiently disrupts propulsion by altering domain asymmetry.
Soft Matter, 2025,21, 6175-6185
https://doi.org/10.1039/D5SM00309A

Home is where the lipids are: a comparison of MSP and DDDG nanodiscs for membrane protein research
DDDG extracts membrane proteins together with native lipids into nanodiscs. These native nanodiscs perform comparably to MSP nanodiscs, with each method suiting different structural and functional studies.
Soft Matter, 2025, Advance Article
https://doi.org/10.1039/D5SM00327J

Windmill droplets: optically induced rotation of biphasic oil-in-water droplets
We report dissipative rotation of oil-in-water biphasic droplets in optical tweezers. Rotation speed can be controlled by the laser power. Untrapped droplets can also be rotated indirectly.
Soft Matter, 2025, Advance Article
https://doi.org/10.1039/D5SM00273G

Dielectrophoretic response and electro-deformation of soft bioparticles interacting with a metallo-dielectric Janus active particle
Active metallo-dielectric Janus particles cause voltage-dependent nuclear electro-deformation, enabling in situ mechanical assessment via surface coverage, with simulations matching experiments using a fitted surface tension parameter.
Soft Matter, 2025, Advance Article
https://doi.org/10.1039/D5SM00462D

Osmocapillary phase separation at contact lines
This paper shows that the solvent phase separation near the contact line of a swollen solid is governed by the competition between osmosis and capillary action instead of the commonly believed competition between elasticity and capillary action.
Soft Matter, 2025, Advance Article
https://doi.org/10.1039/D5SM00325C

Binary mixtures of active Brownian particles with distinct nonzero activities
We computationally study active mixtures with two distinct nonzero activities. We identify three regimes of emergent behaviors (e.g. enhanced avalanche events, microphase separation) and propose the microscopic physical mechanism giving rise to them.
Soft Matter, 2025,21, 6132-6143
https://doi.org/10.1039/D4SM01290A

Cornerstones are the key stones: using interpretable machine learning to probe the clogging process in 2D granular hoppers
Even poor machine learning predictions are useful as experimental guides. We us ML predictions on >50 000 granular clogging events to identify promising experiments which confirm and explain the important role of potential arch cornerstones.
Soft Matter, 2025,21, 6107-6113
https://doi.org/10.1039/D5SM00367A

Molecular mobility of thin films and the adsorbed layer of poly(2-vinylpyridine)
The molecular dynamics of thin films and the adsorbed layer of poly(2-vinylpyridine) were investigated using broadband dielectric spectroscopy and spectroscopic ellipsometry.
Soft Matter, 2025,21, 6120-6131
https://doi.org/10.1039/D5SM00539F

Evolution of adaptive force chains in reconfigurable granular metamaterials
We combine discrete element method simulations, evolutionary algorithms, and experiments to search for granular packings of variable modulus (VM) particles arranged in a triangular lattice with optimal bulk mechanical properties.
Soft Matter, 2025,21, 6088-6099
https://doi.org/10.1039/D4SM00965G

Viscous dissipative energy density as a general adhesion characteristic of adhesive tape
The adhesion energy (Gc) divided by the maximum elongation of the PSA layer (af), which is defined as the viscous dissipative energy density, and the strain rate has a linear relationship on a logarithmic scale, independent of the tape thickness.
Soft Matter, 2025,21, 6078-6087
https://doi.org/10.1039/D5SM00347D

Diverse nanostructures and antimicrobial activity of lipopeptides bearing lysine-rich tripeptide sequences
The self-assembly and conformation in aqueous solution and bioactivity of three lipopeptides bearing lysine-rich tripeptide sequences are compared for C16-KFK, C16-KWK, and C16-KYK, where C16 denotes an N-terminal hexadecyl (palmitoyl) chain.
Soft Matter, 2025,21, 6058-6069
https://doi.org/10.1039/D5SM00432B

Double symmetry breaking in filamentous colloidal tactoids
Under shear flow, filamentous tactoids undergo a double symmetry breaking in both shape and internal director field. The direction of the asymmetry switches when the mesoscopic chirality of the colloids is inverted, revealing how mesoscopic structure governs macroscopic behavior.
Soft Matter, 2025,21, 6039-6046
https://doi.org/10.1039/D5SM00236B

Squaramide-based supramolecular gels for the removal of organic dyes from water matrices
A novel family of symmetric squaramide-based LMWGs has been successfully used for the removal of organic dyes from water matrices.
Soft Matter, 2025,21, 6047-6057
https://doi.org/10.1039/D4SM01538J

Self-consistent field description of polyelectrolyte-grafted colloidal actuators
We present a theoretical model of polyelectrolyte-grafted colloidal actuators, which can expand and contract in response to pH variations.
Soft Matter, 2025, Advance Article
https://doi.org/10.1039/D5SM00474H

Microchannel geometry effects on nematic dowser domain dynamics
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In this study we show how to guide, resize and reshape aligned domains in liquid crystal flow via designed microchannel geometry.
Soft Matter, 2025, Advance Article
https://doi.org/10.1039/D5SM00562K

Optimal first-passage times of active Brownian particles under stochastic resetting
Optimal resetting protocols for active agents are determined by the intricate interplay of resetting, rotational Brownian noise, and active motion.
Soft Matter, 2025,21, 5998-6011
https://doi.org/10.1039/D5SM00340G

Depletion effect in an active chiral system
In a confined two-dimensional geometry shaken vertically, spinning rings immersed in spherical beads exhibit long-range, depletion-like entropic interactions—forming dimers at high bead concentration and repelling at low concentration.
Soft Matter, 2025,21, 5894-5901
https://doi.org/10.1039/D5SM00361J

Molecular architecture modulates self-assembly and micellar rheology of model ionic surfactant systems
We show that micellar solution properties of sodium lauryl ether sulphate surfactants can be described from the average properties of their building blocks. This offers critical insights in understanding and formulating complex surfactant systems.
Soft Matter, 2025,21, 5990-5997
https://doi.org/10.1039/D5SM00252D

E. coli bacterium tumbling in bulk and close to surfaces: a simulation study
E. coli swims by rotating a bundle of helical flagella and tumbles when one reverses its sense of rotation. Using hydrodynamic simulations, we show that near surfaces tumbling causes smaller reorientations and favors the in-plane forward direction.
Soft Matter, 2025,21, 5921-5934
https://doi.org/10.1039/D5SM00371G

Defect dynamics in dry active nematics by residue calculus for holomorphic functions of nematic director field
This paper proposed a new theoretical framework to mathematically model defect motion by constructing integral curves defined from the director field of dry active nematic system based on complex analysis.
Soft Matter, 2025,21, 5947-5956
https://doi.org/10.1039/D5SM00201J

Low-data machine learning models for predicting thermodynamic properties of solid–solid phase transformations in plastic crystals
This study develops low-data machine learning models to predict thermodynamic properties of solid–solid transitions in plastic crystals, identifying key physical descriptors of these materials in sparse-data regimes.
Soft Matter, 2025,21, 5957-5968
https://doi.org/10.1039/D5SM00353A

Winding up dynamics for matched and unmatched elastic constants in chiral nematic liquid crystals
Recently discovered materials have opened up the possibility of easily and repeatably altering the ratio among the elastic constants characterizing nematic liquid crystals.
Soft Matter, 2025,21, 5969-5979
https://doi.org/10.1039/D5SM00373C

Influence of polymer architecture, ionization, and salt annealing on the stiffness of weak polyelectrolyte multilayers
For sufficiently thick PEMs of weak polyelectrolytes assembled in the non-linear growth regime, all-star PEMs showed higher Young’s modulus and were more affected by salt annealing than all-linear PEMs.
Soft Matter, 2025,21, 5883-5893
https://doi.org/10.1039/D5SM00298B

Liquid drop impact on granular beds: the influence of drop inertia and grain size
Droplet impact on granular beds shows two crater regimes set by splash appearance. The influence of grain diameter is unified by a new dimensionless number, capturing inertial dissipation through grain contacts.
Soft Matter, 2025,21, 5935-5946
https://doi.org/10.1039/D4SM00917G

Freedericksz transitions in the nematic and smectic ZA phases of DIO
Freedericksz transitions in the nematic and smectic ZA phases of DIO reveal important information about the elastic properties of this material.
Soft Matter, 2025,21, 5862-5870
https://doi.org/10.1039/D5SM00238A

Dynamics of a bottom-heavy Janus particle near a wall under shear flow
In this study, Brownian dynamics simulations are implemented to investigate the motion of a bottom-heavy, charged Janus particle near a charged wall under varying shear flow conditions.
Soft Matter, 2025,21, 5773-5784
https://doi.org/10.1039/D5SM00229J

Long-range order in two-dimensional systems with fluctuating active stresses
We uncover a new class of two-dimensional active systems with internal stresses which display long-range structural order and hyperuniformity. This notably includes models of two-dimensional biological tissues surrounded by a dissipative medium.
Soft Matter, 2025,21, 5710-5719
https://doi.org/10.1039/D5SM00208G

Statistical mechanics of cell aggregates: explaining the phase transition and paradoxical piezoelectric behavior of soft biological tissues
Piezoelectricity in biological soft tissues is a controversial issue with differing opinions.
Soft Matter, 2025,21, 5655-5668
https://doi.org/10.1039/D5SM00035A

Turbulent-like flows in quasi two-dimensional dense suspensions of motile colloids
Dense suspensions of Quincke random walkers exhibit turbulent-like flows mimicking those of bacterial suspensions.
Soft Matter, 2025, Advance Article
https://doi.org/10.1039/D5SM00192G

Dynamic self-organization in fire ant rafts underpins collective longevity and threat responsiveness
Fire ant rafts dynamically self-organize to conserve energy by separating into active and inactive phases, through formation of stationary clusters that can dissolve rapidly under external stimuli, enabling a swift decentralized collective response.
Soft Matter, 2025, Advance Article
https://doi.org/10.1039/D5SM00390C

SANS and rheology of elongated SDS–DDAO mixed micelles near the phase boundary
SANS and rheology of synergistic SDS–DDAO mixed micelle solutions in the vicinity of the phase boundary exhibit pronounced correlations between structure factor, micelle elongation, and solution viscosity as a function of surfactant mixing ratio.
Soft Matter, 2025,21, 5494-5502
https://doi.org/10.1039/D5SM00437C

Solvent-induced ion clusters generate long-ranged double-layer forces at high ionic strengths
A locally modified restricted primitive model shows enhanced ion clustering, causing significant long-ranged double-layer forces comparable to experiments. These forces stem from cluster–cluster correlations, largely independent of the short-range potential form.
Soft Matter, 2025,21, 5562-5572
https://doi.org/10.1039/D5SM00027K

Brownian dynamics simulation of the diffusion of rod-like nanoparticles in polymeric gels
A rodlike nanoparticle lingers in larger pores of hydrogels, and quickly traverses smaller pores by longitudinal diffusion.
Soft Matter, 2025,21, 5529-5541
https://doi.org/10.1039/D5SM00195A

Oscillatory flow improves hydrodynamic ordering of soft suspensions in rectangular channels
Suspensions of soft particles assemble into train-like structures when flowing in shallow rectangular channels. It is found that oscillatory flow facilitates a significant improvement in the ordered particle arrangements relative to steady flow.
Soft Matter, 2025,21, 5503-5514
https://doi.org/10.1039/D5SM00422E

Capillary-induced adhesive contact dynamics determines dissipation and flow structure in wetted hydrogel packings
The flow behavior of soft, wetted hydrogel particles is affected by the adhesive properties of the particles. We describe their adhesive properties and how adhesion affects their shear banding and dissipation across a range of confining stresses.
Soft Matter, 2025,21, 5468-5479
https://doi.org/10.1039/D5SM00221D

Dynamics and rupture of doped motility induced phase separation
Snapshots showing the slab's movement over time with its boundaries (black line), center of mass X(t) (dashed line), and red/purple particles at source/sink interfaces. Colors persist to track particle positions over time.
Soft Matter, 2025,21, 5413-5422
https://doi.org/10.1039/D5SM00134J

Immobilization and interfacial activation of lipase at liquid and solid interfaces
This work provides a molecular-scale explanation for the increased activity and selectivity of lipase immobilized on silica at water/oil interfaces.
Soft Matter, 2025,21, 5398-5412
https://doi.org/10.1039/D4SM01218F

Shape matters: inferring the motility of confluent cells from static images
We use machine learning to predict single-cell motility in heterogeneous layers using shape features. Our model distinguishes low- from high-motility cells, with potential for physics-inspired predictions from static images of cell dynamics.
Soft Matter, 2025, Advance Article
https://doi.org/10.1039/D5SM00222B

CO2 transport behavior in poly(fluoroalkyl acrylate) and poly(fluoroalkyl methacrylate): a comparative study of fluoropolymer structure–property relationships
A comprehensive understanding of how fluoroalkyl side chains govern CO2 solubility and diffusivity, ultimately impacting gas permeability, is achieved through complementary ATR-FTIR and QCM analyses.
Soft Matter, 2025, Advance Article
https://doi.org/10.1039/D5SM00413F

Mechanics control the proliferation of diatoms entrapped in hydrogels
The growth of microorganisms entrapped in hydrogels is important for biotechnological and natural processes. Using diatoms in agar as model system, this study shows that residual stress regulates the growth of microorganisms inside hydrogels.
Soft Matter, 2025,21, 5359-5370
https://doi.org/10.1039/D5SM00391A

Investigation of microgel monolayers with the colloidal probe technique: how concentration and temperature allow tuning the properties of a microgel coating
PNIPAM-co-APMH microgels and microgel monolayers are investigated by the colloidal probe technique. We show how the microgel concentration affects the softness, charge and stability of the monolayers.
Soft Matter, 2025,21, 5255-5267
https://doi.org/10.1039/D5SM00237K

Morphology prediction for polymer blend thin films using machine learning
Phase-separated morphology plays a pivotal role in determining the potential applications of blend thin films. Machine learning-based classification framework is developed to predict the morphology of PS/PMMA blend thin films.
Soft Matter, 2025,21, 5284-5295
https://doi.org/10.1039/D5SM00335K

Interaction of grain morphology and intergranular friction on grain packing
Our novel approach studies the relationship between grain morphology, intergranular friction, and the jamming packing fraction.
Soft Matter, 2025,21, 5214-5230
https://doi.org/10.1039/D5SM00332F

Modelling the non-linear viscoelastic behaviour of brain tissue in torsion
We develop the first experimental protocol to determine brain tissue's non-linear viscoelastic properties in torsion and validate the results with numerical simulations of the experiments using FEniCS.
Soft Matter, 2025,21, 5268-5283
https://doi.org/10.1039/D5SM00138B

Equilibrium phases and phase transitions in multicritical magnetic polymers
Phase diagram for a magnetic polymer with Blume–Emery–Griffith spins, with snapshots (phases: swollen disordered, SD; compact ordered, CO; compact disordered, CD). These results may be relevant to understand epigenetic memory in chromatin.
Soft Matter, 2025,21, 5296-5311
https://doi.org/10.1039/D5SM00212E
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All featured articles are published Gold Open Access and are free to read in Soft Matter.