RSC Advances  

Analytical technique for monitoring skin-emitted metabolites to diagnose diseases.

Alzheimer has many crucial factors that should be considered in order to get better results from clinical trials. Benzimidazole and its isosteres represent significant scaffolds for designing potential multi-target anti-alzheimer molecules.

The Sn–I metabolite decreases the contractile response to KCl or phenylephrine (PE) mainly by blocking Ca²⁺ entry through voltage-gated Ca²⁺ channel (VGCC).

The new classification of APAP combinations (prodrugs, codrugs, and hybrids) was proposed. It makes a better understanding of the SAR studies for new pain relievers research and the design development for the analgesic APAP-based compounds.

Various nanoformulations of ZnO and Stixis scandens leaf extract were successfully synthesized. The A1T nanoformulation, containing only 7.6% extract, showed an equivalent anti-PEDV activity with the extract.

4-Nonylphenol, an emerging endocrine disruptor, raises health concerns. Radiolabeling and in vivo tracing of 4NP reveal significant tissue accumulation, emphasizing intricate distribution and potential long-term effects for risk assessments.

Silica-coated lanthanide-doped upconverting nanoparticles (UCNPs) are internalized by mammalian cells. The bipyramidal UCNPs are non-toxic and elicit minor stress responses in a cell type-dependent fashion.

S. tangutica extract was obtained by medium-pressure liquid chromatography and its activity studied using HPLC-DPPH screening.

Silver nanoparticles were biosynthesized using extracts from the plant Agrimonia eupatoria. After the characterization, their antioxidant activity, antimicrobial activity, genotoxicity, cytotoxicity, and hemolytic activity were investigated.

Machine learning-powered in silico prediction of small molecule toxicity: a stacked model approach.

In continuation of our program aimed at the discovery and development of natural product-based insecticidal agents, a series of novel nereistoxin derivatives containing phosphonate were synthesized and characterized by ³¹P, ¹H, ¹³C NMR and HRMS.

Understanding archaeological leather degradation helps inform economies, crafts, and technologies of historic communities.

This assay rapidly detects chlorpromazine hydrochloride using its ability to reduce gold ions to form nanoparticles. Its low cost, resilience to interferences and short analysis time could facilitate environmental monitoring and biomedical analysis.

Copper deficiency can trigger various diseases such as Amyotrophic Lateral Sclerosis (ALS), Parkinson's disease (PD) and even compromise the development of living beings, as manifested in Menkes disease (MS).

Astaxanthin/kaempferol co-encapsulated nanoparticles were fabricated using cremophor RH40 and lecithin as surface-active agents, and β-cyclodextrin as an encapsulating agent. The nanoparticles showed high dispersibility and stability in aqueous solutions, which enhances their bioactivity.